High Density Lipoproteins News and Research

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Researchers visualize ruptures of atherosclerotic plaques with multi-color CT and gold nanoparticles

Researchers from Mount Sinai School of Medicine have for the first time developed a way to visualize coronary artery plaques vulnerable to rupture using multi-color computed tomography (CT), an innovation that will lead to better and earlier diagnosis of cardiovascular disease. The data are published in the September issue of Radiology.

17 Aug 2010

Some parts of cholesterol testing for children can be performed without fasting: Study

Physicians usually ask children to fast overnight before a cholesterol test. New research shows that this may not always be necessary.

3 May 2010

Combination of night work, overtime and shortened sleep can increase risk of stroke and heart disease

A new study published in the current issue of Archives of Environmental & Occupational Health (vol. 64, No. 3) shows that this combination of night work, overtime and shortened sleep can contribute to the development among police officers of the metabolic syndrome, a combination of unhealthful factors that increase the risk of cardiovascular disease (CVD), primarily heart disease and stroke.

18 Nov 2009

Upsher-Smith Laboratories publishes results of SLIM Study

Results of the SLIM Study ("Slo-Niacin® and Atorvastatin Treatment of Lipoproteins and Inflammatory Markers in Combined Hyperlipidemia") were recently published in the Journal of Clinical Lipidology.

17 Nov 2009

Upsher-Smith Laboratories publishes data on Slo-Niacin and Lipitor combination study

28 Oct 2009

Low levels of high-density lipoproteins linked to memory loss, dementia risk

Low levels of high-density lipoproteins (HDL) - the "good" cholesterol - in middle age may increase the risk of memory loss and lead to dementia later in life, researchers reported in Arteriosclerosis, Thrombosis and Vascular Biology: Journal of the American Heart Association.

30 Jun 2008

Experimental study on most common form of heart valve disease in Western countries may lead to new treatments

A team of scientists from the University of Montreal and the Montreal Heart Institute Research Centre, led by Dr. Jean-Claude Tardif, has completed an important study that show how a new type of medication can lead to an improvement in the aortic valve narrowing

18 Apr 2008

Malfunctioning kidneys may raise risk of sudden death in women

Women whose kidneys are poor at filtering impurities from the blood are at heightened risk of sudden cardiac death, according to a report published in Hypertension: Journal of the American Heart Association.

8 Apr 2008

Low levels of "good" cholesterol make it difficult to recover from stroke

People are at an increased risk of memory problems and greater disability after stroke if they have low levels of “good” cholesterol and high levels of homocysteine, an amino acid acquired mostly from eating meat.

27 Nov 2007

Older women more knowledgeable about cholesterol than younger women

Older adult American women are better informed about cholesterol and more likely to monitor it than younger adult women, but gaps remain in cholesterol knowledge and efforts to screen for it adequately, according to results of a national survey released by the Society for Women's Health Research, a Washington, D.C., based advocacy organization.

21 Sep 2007

Mechanism for the in-vivo transport of siRNA

It all started with flowers: in the nineties of the last century Norwegian researchers discovered that additional copies of a particular gene in petunias inhibited its activity instead of reinforcing it as had been assumed.

18 Sep 2007

Mouse hibernation hormones described

A key hormone enables starving mice to alter their metabolism and “hibernate” to conserve energy, revealing a novel molecular target for drugs to treat human obesity and metabolic disorders, UT Southwestern Medical Center researchers have found.

8 Jun 2007

Pistachios may decrease a person's cardiovascular disease risk

A handful of pistachios may lower cholesterol and provide the antioxidants usually found in leafy green vegetables and brightly colored fruit, according to a team of researchers.

1 May 2007

Medications plus lifestyle changes work as well as angioplasty to reduce deaths in stable heart-disease patients

Coronary revascularization with stenting or balloon angioplasty combined with optimal medical therapy is no more effective in preventing a heart attack, other major cardiovascular events or death in patients with stable heart disease, than optimal medical therapy alone, results of a new study conducted in 50 hospitals in the U.S. and Canada has shown.

27 Mar 2007

Just one meal high in saturated fat can reduce the ability of the body's "good" cholesterol

Before you bite into that burger or devour that doughnut, first chew on this: New research shows that just one meal high in saturated fat can affect the body's ability to protect itself against some of the underlying causes of heart disease and stroke.

8 Aug 2006

Genetic clues to longevity

In a new study, Drs. Gil Atzmon and Nir Barzilai at the Albert Einstein College of Medicine of Yeshiva University have found that people harbor alleles--alternative forms of a gene--that confer the same sort of longevity advantage.

4 Apr 2006

Social isolation and low mood accelerate coronary disease in women

A study published in the 2006 March issue of Psychotherapy & Psychosomatics by a Swedish group of investigators points to the effects of social isolation and low mood on the progression of coronary disease.

13 Mar 2006

HDLs provide human immunity to certain parasites

For years biomedical researchers have known that high density lipoproteins, commonly called HDLs or "good cholesterol," are responsible for protecting humans from certain parasites, but couldn't explain how.

30 Oct 2005

Researchers find drug targets for treating metabolic syndrome

Ongoing studies by researchers at UT Southwestern Medical Center and other institutions have uncovered the biochemical basis of many of the factors contributing to what is known as the metabolic syndrome, suggesting potential new drug targets for treating the condition.

11 Aug 2005

Researchers identify marker of heart disease in low-birthweight babies

Some low birth weight infants have large particles rich in apolipoprotein C-1, a blood protein that could put them at risk for heart disease later in life, according to a national study led by Johns Hopkins Children's Center researchers.

19 Apr 2005