High throughput screening News and Research

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High-throughput screening (HTS) allows scientists to test thousands of samples at once. These samples can be of a wide variety, and include, but are not limited to, amino acids, chemical compounds or cells.

Piece of puzzle unlocked in what drives alcohol addiction

Researchers at the Scripps Research Institute have made an important discovery that may help to explain the neural mechanism that drives alcohol consumption in cases of addiction.

19 Mar 2019

Scientists reverse alcohol-seeking behavior in rats with flip of a switch

Scientists at Scripps Research have found that they can reverse the desire to drink in alcohol-dependent rats--with the flip of a switch.

19 Mar 2019

USP15 enzyme could potentially lead to new treatments for breast, pancreatic cancer

Researchers at the George Washington University Cancer Center found that the enzyme USP15 could potentially lead to new treatments for breast and pancreatic cancer. Their findings were published in Nature Communications.

15 Mar 2019

“Fail Fast, But More Confidently”: Developing Organoids for Drug Development and Discovery

Richard Eglen discusses the use of organoids in drug discovery, including the screening of candidate compounds for efficacy, toxicity, and pharmacokinetics.

From Corning Life Sciences 13 Mar 2019

Anti-inflammatory drug shown to promote cardiac reprogramming

Once damaged, the human heart does a poor job of repairing itself, so this is a key priority for treating heart failure. One way of restoring cardiac function is to reprogram non-cardiac body cells such as fibroblasts into heart muscle cells (cardiomyocytes) using a collection of cardiac transcription factors.

6 Mar 2019

New optimization method rapidly analyzes nanomedicines for cancer treatment

With their ability to treat a wide a variety of diseases, spherical nucleic acids (SNAs) are poised to revolutionize medicine. But before these digitally designed nanostructures can reach their full potential, researchers need to optimize their various components.

20 Feb 2019

New AI-driven platform analyze how pathogens infect human cells

Researchers have developed a new AI-driven platform that can analyze how pathogens infect our cells with the precision of a trained biologist.

13 Feb 2019

Inhibiting tuberculosis-induced cell death with immunotherapy

Tuberculosis treatment still entails the intake several antibiotics over a period of many months and is torturous for many patients. The pathogen's increasing multidrug resistance additionally complicates this lengthy treatment, and side effects frequently lead to a discontinuation of treatment and high mortality rates.

12 Feb 2019

Corning Life Sciences to highlight advanced 3D cell culture technologies and tools at SLAS 2019

Corning Incorporated will showcase advanced 3D cell culture technologies and workflow solutions, and including those for high throughput screening and ADME/toxicology at SLAS 2019.

From Corning Life Sciences 30 Jan 2019

How Patch Clamp Technology Can Benefit Ion Channel Research

Learn how patch clamp technology meets high-throughput to benefit ion channel research in this interview with Tim and James, Nanion.

From Nanion Technologies 16 Jan 2019

Researchers use INTEGRA's VIAFLO 96/384 to streamline the experimental workflow

Researchers are using INTEGRA’s VIAFLO 96/384 multichannel electronic pipette to study Pseudomonas aeruginosa.

From INTEGRA Biosciences 12 Dec 2018

Research advances offer hope for patient-tailored AML treatment

Advances in rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia.

10 Dec 2018

Forming 3D Neuronal Models of the Brain

In this interview, conducted at SfN 2018, Grischa Chandy from Molecular Devices provides insight on 3D imaging solutions for neuroscience research.

From Molecular Devices, LLC 19 Nov 2018

Researchers develop new strategy in the search for psychoactive drugs

Researchers at the University of Zurich and Harvard University have developed a new strategy in the search for psychoactive drugs.

1 Nov 2018

Antibody Screening Tools; Improving Workflows

Antibody screening tools have exponentially increased the rate that candidates can be screened, multiplexing will increase processing to thousands per hour.¬

From Sartorius 9 Oct 2018

New ReFRAME drug repurposing collection offers hope for treating major diseases

Each year, millions of people worldwide suffer from potentially fatal infectious diseases that often leave survivors facing a lifetime of related health problems. But what if drugs against such diseases already existed but nobody knew it?

4 Oct 2018

QIAGEN and DiaSorin launch automated, CE-marked workflow for high-throughput TB screening

QIAGEN N.V. and DiaSorin today announced the introduction of an automated, CE-marked workflow for QIAGEN’s QuantiFERON-TB Gold Plus Blood Collection Tubes (QFT-Plus BCT) and a novel DiaSorin LIAISON Test on widely used immunodiagnostic instruments from DiaSorin.

17 Sep 2018