High throughput screening News and Research

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High-throughput screening (HTS) allows scientists to test thousands of samples at once. These samples can be of a wide variety, and include, but are not limited to, amino acids, chemical compounds or cells.

Household chemicals endanger brain's myelin-forming cells

Study uncovers how environmental chemicals, specifically organophosphate flame retardants and quaternary compounds, negatively affect oligodendrocyte development, implicating them in potential neurodevelopmental risks such as ADHD and autism, by employing an innovative high-throughput screening approach on mouse and human stem cell-derived models.

26 Mar 2024

Arrayjet’s ArrayPlex platform selected by Immunome for use in its discovery of targeted cancer therapies

Immunome signs deal to use Arrayjet platform in its in-house screening operations.

From Arrayjet Ltd 18 Mar 2024

Universal screening of congenital cytomegalovirus infection with pooled saliva tests

New study displays successful implementation of pooled saliva tests for universal screening of congenital cytomegalovirus (cCMV) infection.

12 Mar 2024

Researchers forge new path to combat viruses and cancers with helicase inhibitors

Helicases are enzymes that unwind DNA and RNA. They're central to cellular life, implicated in a number of cancers and infections-;and, alas, extraordinarily difficult to target with drugs.

9 Mar 2024

Breakthrough in CRISPR delivery promises safer gene editing

Recent research in PNAS highlights advancements in non-viral, cell-specific delivery methods for CRISPR-Cas systems, emphasizing their potential to enhance research and gene therapy applications by minimizing risks associated with off-target effects and improving targeted delivery.

7 Mar 2024

SCIEX’s Jose Castro-Perez Reveals How They're Setting New Standards in Mass Spectrometry

SCIEX’s Reveals How They're Setting New Standards in Mass Spectrometry at SLAS 2024.

From Society for Laboratory Automation and Screening (SLAS) 22 Feb 2024

Academia's drug discovery challenges: Exploring the "publication landfill"

A new editorial paper was published in Oncotarget's Volume 15 on January 24, 2024, entitled, "The fate of drug discovery in academia; dumping in the publication landfill?"

6 Feb 2024

Hamamatsu introduces the New FDSS-GX: the highest-performance kinetic plate imager in the FDSS series

Hamamatsu Photonics announces the release of a new high-speed kinetic plate imager, the FDSS-GX.

From Hamamatsu Photonics Europe 5 Feb 2024

SCIEX expands high-throughput screening solutions with Echoâ MS+ system

The Echo® MS+ system unlocks enhanced high-throughput screening capability by bringing acoustic ejection mass spectrometry (AEMS) approaches to the SCIEX ZenoTOF 7600 system.

From SCIEX 5 Feb 2024

Bacteria's "suicidal" immune system boosts antibiotic power against cholera

Bacteria have an immune system that protects them against viruses known as bacteriophages. A research team from the Universities of Tübingen and Würzburg has now shown how this immune system enhances the effect of specific antibiotics against the cholera pathogen Vibrio cholerae.

19 Jan 2024

When mass spectrometry redefines the pharma industry

In this new episode of omg OMx, Kate Stumpo speaks to Bruker's Mike Greig about the incredible potential of mass spectrometry in pharma.

From Bruker Life Sciences Mass Spectrometry 12 Jan 2024

New method designs high-affinity, orally bioavailable peptides

For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy.

28 Dec 2023

Deep learning unlocks new antibiotic classes, revolutionizing the fight against resistance

A Nature journal study employs deep learning to analyze chemical sub-structures, leading to the discovery of new structural classes of antibiotics, showcasing the potential of AI in accelerating antibiotic development.

20 Dec 2023

Arxspan BioDrive: A Versatile Solution for Molecular Biology

In this interview, NewsMedical speaks to Arxspan about its new all-in-one solution for molecular biology.

From Arxspan 5 Dec 2023

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Research explores the advancements, challenges, and economic implications of gene therapy for various diseases, including inherited blood disorders, malignancies treated with CAR-T cells, and diseases targeted by in vivo AAV vectors. The review highlights the transformative potential of gene therapies while acknowledging the complexities in manufacturing, safety, efficacy, and long-term durability.

12 Nov 2023

Could CaMKK2 enzyme be the key to treating bipolar disorder?

Researchers explore the role of the CaMKK2 signaling pathway in bipolar disorder, suggesting it as a new treatment target. By targeting this enzyme, scientists aim to develop more effective therapies for bipolar symptoms and metabolic dysfunction.

24 Sep 2023

Innovative technique provides unparalleled insight into autism pathology

Does the human brain have an Achilles heel that ultimately leads to Autism? With a revolutionizing novel system that combines brain organoid technology and intricate genetics, researchers can now comprehensively test the effect of multiple mutations in parallel and at a single-cell level within human brain organoids.

13 Sep 2023