Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

New studies examine the effects of napping on infant and preschooler brain development

A University of Massachusetts Amherst sleep scientist, funded with $6.7 million in grants from the National Institutes of Health, has launched two unprecedented studies that will track over time the brain development of infants and preschoolers to confirm the role of napping in early life and to identify the bioregulatory mechanisms involved.

25 Apr 2024

Study reveals surprising role of maternal cytokines in offspring psychiatric risk

Researchers at Weill Cornell Medicine have discovered in a preclinical model that cytokines, proteins that control immune response, circulating in maternal blood during pregnancy may mitigate an offspring's risk for psychiatric conditions.

25 Apr 2024

Young mouse plasma found to reverse aging in older mice

Researchers demonstrate that small extracellular vesicles (sEVs) from young mice plasma can reverse aging effects in older mice by enhancing mitochondrial function and energy metabolism.

22 Apr 2024

Animal study suggests early Western diet exposure linked to lasting memory issues

Researchers find that early exposure to a Western diet in rats leads to long-lasting impairments in hippocampus-dependent memory, mediated by disruptions in acetylcholine signaling.

18 Apr 2024

Study reveals neuronal mechanisms behind working memory

Cedars-Sinai investigators have discovered how brain cells responsible for working memory-;the type required to remember a phone number long enough to dial it-;coordinate intentional focus and short-term storage of information.

17 Apr 2024

Junk food-filled diet in teens may disrupt brains' memory ability for a long time

A new USC-led study on rats that feasted on a high-fat, sugary diet raises the possibility that a junk food-filled diet in teens may disrupt their brains' memory ability for a long time.

16 Apr 2024

Poverty and low socioeconomic status affect cognitive development, mental health

What determines mental health, school performance, and even cognitive development? A new review in De Gruyter's Reviews in the Neurosciences suggests that poverty and low socioeconomic status (SES) are key contributory factors.

15 Apr 2024

Geraniol alleviates cognitive decline in D-galactose-induced aging mice

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 6, entitled, "Geraniol attenuates oxidative stress and neuroinflammation-mediated cognitive impairment in D galactose-induced mouse aging model."

12 Apr 2024

Genetic link between PTSD and Alzheimer's debunked in veterans study

Study reveals that the genetic risk factor for Alzheimer’s disease, APOE ε4, does not increase PTSD risk among combat veterans, challenging the previously suggested link between PTSD and future dementia.

7 Apr 2024

Mitochondrial fusion critical for adult neurogenesis and brain circuit refinement

Nerve cells (neurons) are amongst the most complex cell types in our body. They achieve this complexity during development by extending ramified branches called dendrites and axons and establishing thousands of synapses to form intricate networks.

5 Apr 2024

Interferon-beta deficiency alters brain response in neuroHIV mouse model

NeuroHIV refers to the effects of HIV infection on the brain or central nervous system and, to some extent, the spinal cord and peripheral nervous system.

4 Apr 2024

Sweet truths and bitter pills: How free sugars affect human health

The current evidence about the effect of free sugars on health outcomes in humans, including mood, cognition, cardiovascular disease, diabetes, and obesity.

3 Apr 2024

DNA repair process key to memory formation, study finds

Study reveals that learning triggers a series of molecular events including DNA damage and repair in hippocampal neurons, mediated by TLR9, crucial for memory formation.

31 Mar 2024

How neural barcodes shape episodic memory in chickadees

Black-capped chickadees have extraordinary memories that can recall the locations of thousands of morsels of food to help them survive the winter.

29 Mar 2024

Unveiling the brain mechanism behind memory consolidation in sleep

Neuroscientists have established in recent decades the idea that some of each day's experiences are converted by the brain into permanent memories during sleep the same night.

28 Mar 2024

Transformative epilepsy surgery gives artist new lease on life

Artist Syril Strickler was 47 when she had her first epileptic seizure, waking up in the hospital after neighbors found her unconscious in the street.

28 Mar 2024

DNA damage in neurons crucial for creating stable memories

Just as you can't make an omelet without breaking eggs, scientists at Albert Einstein College of Medicine have found that you can't make long-term memories without DNA damage and brain inflammation. Their surprising findings were published online today in the journal Nature.

27 Mar 2024

Researchers explore link between tooth loss and denture usage, diet changes and cognitive decline

A recent npj Aging study assessed the specific brain regions that are impacted by tooth loss and the associated causes.

25 Mar 2024

Novel treatment approach to halt epilepsy progression identified

Only a very small percentage of neurons show changes after an epileptic seizure in mice, but these alterations can be permanent and trigger future seizures that can affect the whole brain and lead to impaired cognition, like memory and learning, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

22 Mar 2024

Middle age: A critical turning point for brain health and cognition

Review emphasizes the significance of midlife for cognitive trajectories and brain health, advocating for research models that capture non-linear changes to better understand the unique processes occurring during this period.

20 Mar 2024