Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Studies reveal functioning of nerve cells in entorhinal cortex

The entorhinal cortex is a link between the brain's memory centre, the hippocampus, and the other areas of the brain. It is, however, more than an interface that only transfers nervous impulses.

20 Sep 2013

Research discovery suggests whole new frontier in human and animal brain functioning

Researchers from the University of Montreal and their colleagues have found brain activity beyond a flat line EEG, which they have called Nu-complexes (from the Greek letter).

19 Sep 2013

New information about how estrogens regulate memory formation

The loss of estrogens at menopause increases a woman's risk of dementia and Alzheimer's disease, yet hormone replacement therapy can cause harmful side effects.

19 Sep 2013

Discovery of gene essential for memory extinction could lead to new PTSD treatments

If you got beat up by a bully on your walk home from school every day, you would probably become very afraid of the spot where you usually met him. However, if the bully moved out of town, you would gradually cease to fear that area.

19 Sep 2013

Study reveals olive leaf extract can inhibit lead-induced brain injury

In recent years, neurotoxicity from exposure to low levels of lead in the environment has become increasingly prevalent. Therefore, the discovery of herbs that have lead-eliminating properties without harmful side effects is essential for the management of lead poisoning.

17 Sep 2013

Research suggests possibility of using cell transplants to treat schizophrenia

Research from the School of Medicine at The University of Texas Health Science Center at San Antonio suggests the exciting possibility of using cell transplants to treat schizophrenia.

10 Sep 2013

Degeneration of fornix in brain may provide clues to future cognitive decline in healthy old people

The degeneration of a small, wishbone-shaped structure deep inside the brain may provide the earliest clues to future cognitive decline, long before healthy older people exhibit clinical symptoms of memory loss or dementia, a study by researchers with the UC Davis Alzheimer's Disease Center has found.

10 Sep 2013

Locus coeruleus plays major role in learning, memory and other cognitive functions

Death of neurons in the dorsal raphe nucleus and locus coeruleus is a pathological characteristic of the disease. Previous studies concerning the pathological characteristic of Alzheimer's disease mainly focus on learning and memory-related hippocampus, and less attention has been paid to the locus coeruleus.

6 Sep 2013

Resveratrol improves cognition and reduces oxidative stress in rats with vascular dementia

Resveratrol, a polyphenolic compound, is synthesized in several plants and possesses beneficial biological effects, which include anti-oxidant, anti-inflammatory and anti-carcinogenic properties.

5 Sep 2013

Study: Deficiency of protein causes age-related memory loss and Alzheimer's disease

A team of Columbia University Medical Center (CUMC) researchers, led by Nobel laureate Eric R. Kandel, MD, has found that deficiency of a protein called RbAp48 in the hippocampus is a significant contributor to age-related memory loss and that this form of memory loss is reversible.

29 Aug 2013

Alzheimer’s drug trial: an interview with Geoffrey Kempler, Chairman & CEO Prana Biotechnology

Approval for the IMAGINE trial was granted by the Austin Health Research Ethics Committee in November 2011, with the first patients dosed in March the following year. However, well before the trial was approved, PBT2 had already shown promise in significantly changing Abeta levels in spinal fluid while improving cognition in a previous 12-week trial conducted in 2006.

28 Aug 2013

Research shows specific form of memory associations is encoded in cerebral cortex

'Where' and 'how' memories are encoded in a nervous system is one of the most challenging questions in biological research. The formation and recall of associative memories is essential for an independent life. The hippocampus has long been considered a centre in the brain for the long-term storage of spatial associations.

28 Aug 2013

Stem cell therapy improves radiation-induced cognitive impairment

Patients receiving cranial irradiation treatment for brain cancer may find the treatment life-saving, but often suffer progressive and debilitating cognitive detriments, including spatial learning and memory deficits. The cognitive deficits are a contributing factor to the often significant adverse impacts on the surviving patients' quality of life after radiation therapy. In an effort to improve post-irradiation cognitive impairment, scientists at the University of California, Irvine, and colleagues at Neuralstem, Inc. (Rockville, MD), have transplanted fetal stem cells into laboratory animals with radiation-induced cognitive impairments and found that this led to a number of cognitive improvements.

23 Aug 2013

Brain Study Suggests New Way To Treat Anxiety

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22 Aug 2013

Psychogenics Picks Up Alzheimer’s Animal Model From USF

PsychoGenics obtained an exclusive license from the University of South Florida to its APP/PS1 double transgenic mice, which co-express the M146L presenilin 1 (PS1) mutation and the double mutations at K670N/M671L (Swedish mutation) in the amyloid precursor protein (APP).

22 Aug 2013

In dynamic mind-body interaction, brain recruits cells from immune system to promote anxiety

New research shows that in a dynamic mind-body interaction during the interpretation of prolonged stress, cells from the immune system are recruited to the brain and promote symptoms of anxiety.

22 Aug 2013

Research reveals that brain circuits can help reduce anxiety disorders

Anxiety disorders, which include posttraumatic stress disorder, social phobias and obsessive-compulsive disorder, affect 40 million American adults in a given year. Currently available treatments, such as antianxiety drugs, are not always effective and have unwanted side effects.

22 Aug 2013

UCLA study suggests third possible cause for AD: Iron accumulation

Alzheimer's disease has proven to be a difficult enemy to defeat. After all, aging is the No. 1 risk factor for the disorder, and there's no stopping that.

21 Aug 2013

Researchers create mouse models to advance the study of unusual deadly diseases

By directly manipulating a portion of the prion protein-coding gene, Whitehead Institute researchers have created mouse models of two neurodegenerative diseases that are fatal in humans. The highly accurate reproduction of disease pathology seen with these models should advance the study of these unusual but deadly diseases.

20 Aug 2013

Study: H3 receptor antagonist can improve brain edema in adult hypoxic rats

Thioperamide, a selective histamine H3 receptor antagonist, can increase histamine content in the brain and improve brain edema in adult hypoxic rats. Brain edema is precisely considered as the important pathological change of neonatal hypoxic-ischemic encephalopathy.

13 Aug 2013

Hippocampus News and Research

Further Reading

Studies reveal functioning of nerve cells in entorhinal cortex

Research discovery suggests whole new frontier in human and animal brain functioning

New information about how estrogens regulate memory formation

Discovery of gene essential for memory extinction could lead to new PTSD treatments

Study reveals olive leaf extract can inhibit lead-induced brain injury

Research suggests possibility of using cell transplants to treat schizophrenia

Degeneration of fornix in brain may provide clues to future cognitive decline in healthy old people

Locus coeruleus plays major role in learning, memory and other cognitive functions

Resveratrol improves cognition and reduces oxidative stress in rats with vascular dementia

Study: Deficiency of protein causes age-related memory loss and Alzheimer's disease

Alzheimer’s drug trial: an interview with Geoffrey Kempler, Chairman & CEO Prana Biotechnology

Research shows specific form of memory associations is encoded in cerebral cortex

Stem cell therapy improves radiation-induced cognitive impairment

Brain Study Suggests New Way To Treat Anxiety

Psychogenics Picks Up Alzheimer’s Animal Model From USF

In dynamic mind-body interaction, brain recruits cells from immune system to promote anxiety

Research reveals that brain circuits can help reduce anxiety disorders

UCLA study suggests third possible cause for AD: Iron accumulation

Researchers create mouse models to advance the study of unusual deadly diseases

Study: H3 receptor antagonist can improve brain edema in adult hypoxic rats

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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