Histamine News and Research

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Histamine is a biogenic amine chemical involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.

Long-term use of proton pump inhibitors associated with increased risk of dementia

Researchers determine whether the current and cumulative use of prescription proton pump inhibitors increases the risk of incident dementia.

17 Aug 2023

Mast cells act as sensors to help avoid harmful antigens

The function of mast cells, which are part of the immune system, is still a mystery. Scientists at the German Cancer Research Center (DKFZ) have now shown in mice: mast cells function as a sensor that signals the animals to avoid antigens, including harmful allergens, and thereby protect themselves from health-threatening inflammatory reactions.

12 Jul 2023

Study suggests the role of histamine-releasing factor in severe asthma and RV-induced asthma exacerbation

Asthma is more dangerous than many people realize. An estimated 10 Americans die everyday from asthma, and the disease leads to around 439,000 hospitalizations and 1.3 million emergency room trips each year.

12 Jun 2023

How to combat and lessen seasonal allergy symptoms

Welcoming spring this year has been bittersweet for the millions of allergy sufferers already experiencing itchy eyes, nasal congestion, sneezing and runny noses.

13 Apr 2023

People with asthma or eczema more likely to develop osteoarthritis

Stanford Medicine scientists and their colleagues have found that having asthma or eczema increases the likelihood of developing osteoarthritis — signaling that there may be an allergic pathway that can be targeted with existing drugs.

28 Mar 2023

Investigating how gut microbiota affect neuroplasticity and neurodevelopment

In a recent study published in the journal Neuropharmacology, researchers in Pisa, Italy, explored how gut microbiota can influence neuroplasticity.

20 Mar 2023

How does alcohol affect blood pressure?

Drinking is part of human society worldwide. However, alcohol consumption has been strongly linked to human diseases, including dementia, liver cirrhosis, and neurological conditions. A recent research paper examined whether drinking was related to hypertension, the root factor in morbidity and mortality caused by cardiovascular disease (CVD).

16 Feb 2023

Study reviews mechanistic data on new methods of allergy prevention and treatment

In a recent article published in Science Translational Medicine, researchers reviewed the cause and the underlying pathophysiology of allergic diseases.

23 Jan 2023

Valuable tool reveals the connections between gut microbes and the brain

In the past decade, researchers have begun to appreciate the importance of a two-way communication that occurs between microbes in the gastrointestinal tract and the brain, known as the gut–brain axis.

13 Jan 2023

Flavonoids with potential to fight allergies and inflammation

In a recent study published in the Biomedicine & Pharmacotherapy journal, researchers explored the anti-allergic and anti-inflammatory properties of flavonoids.

28 Nov 2022

Study sheds new light on the role of IgA in food allergies

Food-specific immunoglobulin A present in the human gut does not provide protection against food allergies.

27 Nov 2022

Infancy acid suppression and antibiotic use are associated with celiac disease

Researchers determine whether exposure to certain prescriptions after the first six months of life was associated with a diagnosis of celiac disease.

20 Oct 2022

Exposure to blue light may accelerate aging

A new study provides insights into the novel mechanisms through which blue light exposure interferes with non-retinal cell metabolic pathways in flies.

5 Sep 2022

Azelastine nasal spray could decrease SARS-CoV-2 load

A new study illustrated that early azelastine nasal spray therapy might lower the SARS-CoV-2 load among virus-infected patients.

11 Aug 2022

Gut bacterial 'super-producer' of histamine can cause pain flare-ups in some IBS patients

Researchers from McMaster University and Queen's University have discovered a gut bacterial 'super-producer' of histamine that can cause pain flare-ups in some patients with irritable bowel syndrome (IBS).

27 Jul 2022

What causes insomnia and how to treat it?

A new study evaluates the symptoms of insomnia and its treatment as reported by patients in primary care settings.

5 Jul 2022

How do mosquito bites affect immunity?

A new study looks at the immunomodulatory effects of mosquito bites, using Aedes aegypti as the model species and humans as the host.

28 Apr 2022

New test greatly simplifies the diagnosis of allergies

Although allergies are widespread, their diagnosis is complex and, depending on the type of allergy, the prospects of success with therapy are not always clear.

21 Mar 2022

Study shows anti-itch and pain relief potential of protein in tick saliva

A protein found in tick saliva could be turned into a drug that eases itching and chronic pain in people.

8 Mar 2022

Antihistamines may offer hope for long COVID patients

Researchers offer hope that an inexpensive over-the-counter medication could improve long COVID symptoms for a large proportion of these patients.

14 Feb 2022