Histamine News and Research

RSS

Histamine is a biogenic amine chemical involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.

Protein a possible key to allergy and asthma control

Activating a protein found on some immune cells seems to halt the cells' typical job of spewing out substances that launch allergic reactions, a study by Johns Hopkins researchers suggests.

3 Jan 2008

Heartburn during pregnancy

Heartburn symptoms are one of the most commonly reported complaints among pregnant women.

10 Dec 2007

New test detects the presence of biogenic amines

Researchers in California are reporting development of a fast, inexpensive test suitable for home use that could help millions of people avoid those 'out of the blue' headaches that may follow consumption of certain red wines, cheese, chocolate, and other aged or fermented foods.

2 Oct 2007

Cell that triggers symptoms in allergy attacks can also limit damage

A blood cell known as a troublemaker for triggering the itch and inflammation in allergy attacks, the mast cell, can also calm down the flare-ups, researchers from Stanford University School of Medicine have found.

3 Sep 2007

New approach for tackling allergies

Allergies, like the common cold and asthma, have basically defied the best efforts of modern medicine to cure them.

28 Jun 2007

Researchers discover why antipsychotic drugs cause weight gain

Researchers at Johns Hopkins University in Baltimore have discovered why some drugs used to treat mental illnesses such as schizophrenia, cause patients to gain a lot of weight.

13 Feb 2007

Lung neutrophils produce histamine in significant quantities

In a surprise finding, scientists have discovered that histamine, the inflammatory compound released during allergic reactions that causes runny nose, watery eyes, and wheezing, can be produced in large amounts in the lung by neutrophils, the white blood cells that are the major component of pus.

14 Jan 2007

Transport mechanism of bioactive molecule, S1P, identified

Virginia Commonwealth University researchers have identified how a bioactive molecule involved with allergy, inflammation and cancer is transported out of mast cells, according to findings published online this week in the Proceedings of the National Academy of Sciences.

17 Oct 2006

"Allergy cells" can aggravate cancer and psoriasis

The body's mast cells are mainly associated with allergic reaction in the way they release histamine and other inflammatory substances.

13 Sep 2006

Trying to improve on the activity of Interferon-Alpha in metastatic renal cell carcinoma

Interferon-alpha (IFN) has been a mainstay in the systemic treatment of metastatic renal cell carcinoma (RCC) for decades, with response rates ranging from 3-15%.

16 Aug 2006

Unexpected rheumatoid arthritis discovery

What makes joints in people with rheumatoid arthritis, and related conditions like Lyme disease or lupus, so susceptible to attack by the body's immune system, leading to painful flare-ups and deterioration? The answer may surprise you.

17 Feb 2006

Fruits and vegetables can increase or decrease the activity and toxicity of orally-administered drugs

Eating fruits and vegetables is essential to living a long and healthy life, yet research has shown they can cause dangerous interactions with medicines.

5 Oct 2005

Relationship between allergies and mold spores in lawns

"Have you ever driven down the road and seen someone mowing the lawn wearing a mask? This is an example of the relationship between allergies and mold spores in lawns. Dr. Phil Colbaugh, research plant pathologist at the Texas Agricultural Experiment Station in Dallas, cites a common image seen in Texas throughout the warm weather months.

2 Aug 2005

New process removes allergy potential from peanut products

Scientists say a special fermentation process may significantly reduce the potential for allergic reaction to peanut products.

6 Jun 2005

New therapy for treating cat allergies looks promising

Andrew Saxon, M.D., and a team of researchers at University of California, Los Angeles (UCLA) have found that a molecule designed to block cat allergies can prevent allergic reactions in laboratory mice and was also successful when tested on human cells in a test tube.

28 Mar 2005

Treatment to control gastroesophageal reflux disease in children found to be ineffective

According to a study published in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology, more than 60 percent of the children who received surgical fundoplication to control gastroesophageal reflux disease (GERD) had recurring symptoms of the disease months following surgery.

4 Nov 2004

Maxim Pharmaceuticals to withdraw NDA for advanced malignant melanoma

Maxim Pharmaceuticals has announced that based upon the negative outcome of it's confirmatory Phase 3 clinical trial (M0104) studying Ceplene(TM) (histamine dihydrochloride) in combination with Interleukin-2 (IL-2) in advanced malignant melanoma patients with liver metastases, it plans to close the treatment protocol approved by the FDA earlier this year.

2 Nov 2004