Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

International trial confirms long-term benefits of anastrozole to stop breast cancer

A major international trial has confirmed the long-term benefit of anastrozole to help stop breast cancer coming back or developing in the other breast in postmenopausal women with hormone sensitive early breast cancer, according to a study published in Lancet Oncology today (Wednesday).

2 Dec 2010

Study identifies new genes responsible for early menarche

University of Minnesota School of Public Health researcher Ellen Demerath, Ph.D., is among an international group of researchers that has identified 30 new genes responsible for determining the age of sexual maturation in women. Many of these genes are also known to influence body fatness, obesity, and energy metabolism. Prior to the multi-institutional study, only four genes had been identified as contributing to the process.

1 Dec 2010

British Journal: Obesity, alcohol consumption may increase cancer risk

People should be warned that cancer is linked to obesity and alcohol, rather than urged to eat more fruit and vegetables to protect against the disease.

1 Dec 2010

Debiopharm recognised with European Biopharmaceuticals company of the year award

The 2010 Frost & Sullivan Europe Company of the Year Award in Biopharmaceuticals is presented to Debiopharm Group™ (Debiopharm).

1 Dec 2010

Diabetes plays a vital role in regulating brain cholesterol: Research

The brain contains more cholesterol than any other organ in the body, has to produce its own cholesterol and won't function normally if it doesn't churn out enough. Defects in cholesterol metabolism have been linked with Alzheimer's disease and other neurodegenerative conditions. Now researchers at Joslin Diabetes Center have discovered that diabetes can affect how much cholesterol the brain can make.

1 Dec 2010

Research could lead to new drug treatment for metabolic diseases

A team of Harvard School of Public Health (HSPH) scientists report finding a molecular "switch" that can "turn off" some cellular processes that are protective against aging and metabolic diseases. While more research is needed, the findings may open doors for new drug treatments to halt or slow development of metabolic diseases like type 2 diabetes or heart disease. The research findings appear in the December 1, 2010 issue of Cell Metabolism.

1 Dec 2010

Vitamin D supplementation may reduce risk of diabetes, heart disease: Research

Researchers from the UC Davis Health System have found that compared with healthy controls, blood levels of vitamin D are significantly reduced in patients in the Sacramento area with metabolic syndrome, a constellation of disease risk factors that affects about one in three U.S. adults and predisposes them to diabetes, heart disease and stroke.

1 Dec 2010

Men with long index fingers at lower risk of prostate cancer

Men who have long index fingers are at lower risk of prostate cancer, a new study published today in the British Journal of Cancer has found.

1 Dec 2010

Study shows link between reduced hormone therapy and decline in breast cancer

In a new UCSF study of more than 2 million mammogram screenings performed on nearly 700,000 women in the United States, scientists for the first time show a direct link between reduced hormone therapy and declines in ductal carcinoma in situ (DCIS) as well as invasive breast cancer. The researchers saw such a striking decrease, they believe they also have uncovered indirect evidence that hormones promote breast tumor growth.

1 Dec 2010

FG-2216 drug offers new treatment option for kidney disease-related anemia

A new drug called FG-2216 can stimulate production of the hormone erythropoietin (EPO) in dialysis patients—possibly offering a new approach to treatment of kidney disease-related anemia, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

30 Nov 2010

New findings could drive medical advances in genetic disorders that cause infertility

A hormone responsible for the onset of puberty can end up stuck in the wrong part of the body if the nerve pathways responsible for its transport to the brain fail to develop properly, according to research funded by the Biotechnology and Biological Sciences Research Council (BBSRC).

30 Nov 2010

Medivation, Astellas enroll 1,199 patients in MDV3100 Phase 3 AFFIRM study in advanced prostate cancer

Medivation, Inc. and Astellas Pharma Inc. today announced that patient enrollment was completed on November 15, 2010 in the Phase 3 AFFIRM study of the investigational drug MDV3100, a novel, triple-acting oral androgen receptor antagonist, in patients with advanced prostate cancer who have previously been treated with chemotherapy. The companies also announced that clinical development of MDV3100 in Japan has commenced, with the initiation of patient dosing in a Phase 1-2 clinical study.

30 Nov 2010

Depressed and suicidal individuals linked to low levels of stress hormone cortisol

Depressed and suicidal individuals have low levels of the stress hormone cortisol in their blood and saliva. They also have substances in their spinal fluid that suggest there is increased inflammation in the brain. These findings could help to develop new methods for diagnosing and treating suicidal patients.

29 Nov 2010

Study finds association between DGKK gene and hypospadias

Hypospadias is a common congenital malformation of the male external genitalia, affecting 1 in 375 boys. In hypospadias patients, the urethral opening is not located at the tip of the penis, but somewhere halfway, at the base of the penis, or even in the scrotum.

29 Nov 2010

Overexposure to triclosan may negatively influence immune system: Study

Young people who are overexposed to antibacterial soaps containing triclosan may suffer more allergies, and exposure to higher levels of Bisphenol A among adults may negatively influence the immune system, a new University of Michigan School of Public Health study suggests.

29 Nov 2010

Serono Symposium to review options available for optimizing Assisted Reproductive Technologies

Serono Symposia International Foundation will gather a team of leading international experts meeting on November 26th in Montreal in order to review the different options currently available to optimize ART (Assisted Reproductive Technologies) outcomes during the event "Treating the Ovary to Obtain Better Eggs".

26 Nov 2010

Study suggests less than 10% of UK adults with CAH receive specialist endocrine care

A new study suggests that less than 10% of the estimated 3,591 adults in the UK with the genetic condition congenital adrenal hyperplasia (CAH) receive specialist endocrine care, and that there is no standard treatment for these patients.

26 Nov 2010

Use of aspirin and statins can reduce depression: Study

A study that appears in the current issue of Psychotherapy and Psychosomatics addresses the association between use of aspirin and statins and the risk of major depression.

25 Nov 2010

Researchers explain molecular mechanism that induces HER2+ tumours to ignore cell signals

About 30% of breast cancer patients have tumours that show rapid growth and invasion through the body. A common denominator in all of these cases is the presence of a large number of Her2 proteins in tumour cellular membranes. Consequently, these aggressive tumours are referred to as HER2+. Scientists working in the Metastasis Laboratory (MetLab) at IRB Barcelona headed by ICREA researcher Roger Gomis, have described the molecular mechanism that induces HER2+ tumours to ignore the signals that protect cells from excessive growth.

25 Nov 2010

Chronic jet lag alters brain's intricate role in memory processing

Chronic jet lag alters the brain in ways that cause memory and learning problems long after one's return to a regular 24-hour schedule, according to research by University of California, Berkeley, psychologists.

25 Nov 2010

Hormone News and Research

Further Reading

International trial confirms long-term benefits of anastrozole to stop breast cancer

Study identifies new genes responsible for early menarche

British Journal: Obesity, alcohol consumption may increase cancer risk

Debiopharm recognised with European Biopharmaceuticals company of the year award

Diabetes plays a vital role in regulating brain cholesterol: Research

Research could lead to new drug treatment for metabolic diseases

Vitamin D supplementation may reduce risk of diabetes, heart disease: Research

Men with long index fingers at lower risk of prostate cancer

Study shows link between reduced hormone therapy and decline in breast cancer

FG-2216 drug offers new treatment option for kidney disease-related anemia

New findings could drive medical advances in genetic disorders that cause infertility

Medivation, Astellas enroll 1,199 patients in MDV3100 Phase 3 AFFIRM study in advanced prostate cancer

Depressed and suicidal individuals linked to low levels of stress hormone cortisol

Study finds association between DGKK gene and hypospadias

Overexposure to triclosan may negatively influence immune system: Study

Serono Symposium to review options available for optimizing Assisted Reproductive Technologies

Study suggests less than 10% of UK adults with CAH receive specialist endocrine care

Use of aspirin and statins can reduce depression: Study

Researchers explain molecular mechanism that induces HER2+ tumours to ignore cell signals

Chronic jet lag alters brain's intricate role in memory processing

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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