Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

Study examines associations of different fats and subtypes of ischemic stroke in post-menopausal women

Post-menopausal women who reported consuming the most daily dietary fat had a 40 percent higher incidence of clot-caused strokes compared to women who ate the least amount, according to research presented at the American Stroke Association's International Stroke Conference 2010.

25 Feb 2010

INMA researchers study the consequences iodine supplements in pregnant women

Iodine is an essential element for synthesising thyroid hormones. A team of researchers from the Childhood and Environment Project has studied the consequences of pregnant women consuming it in their diet and in supplements. The results suggest the need to evaluate their iodine nutritional status before systematically recommending taking it during pregnancy.

24 Feb 2010

Scientists identify key mechanism of drug resistance in breast cancer patients

CANCER RESEARCH UK funded scientists have discovered why some breast cancers are resistant to the commonly used drug tamoxifen, their findings are published in Cancer Research.

24 Feb 2010

Depression and stress hormone levels may lead to obesity in girls

Depression raises stress hormone levels in adolescent boys and girls but may lead to obesity only in girls, according to researchers. Early treatment of depression could help reduce stress and control obesity -- a major health issue.

24 Feb 2010

Woman's risk of heart disease intensifies during natural menopause: Study

When women hear the word menopause, they often think about hot flashes, hormone shifts and mood swings. But what about heart disease? Studies show a woman's risk of heart disease intensifies drastically around the time of natural menopause, which for most women is around the age of 50.

24 Feb 2010

Older diabetes patients with high stress levels are more likely to experience memory loss

Researchers at the University of Edinburgh studied more than 900 men and women aged between 60 and 75 with type-2 diabetes, which tends to be common after the age of 40.

23 Feb 2010

Amylin Pharmaceuticals and Takeda Pharmaceutical to advance pramlintide/metreleptin combination therapy development

Amylin Pharmaceuticals, Inc. and Takeda Pharmaceutical Company Limited announced today that the companies have selected the combination treatment of pramlintide, an analog of the natural hormone amylin, and metreleptin, an analog of the natural hormone leptin, for advancement toward Phase 3 development. The decision to advance the program followed encouraging results from a 52-week blinded, placebo-controlled Phase 2 extension study. The pramlintide/metreleptin combination met the key target criteria of sustained and robust weight loss.

23 Feb 2010

Amgen's Prolia Complete Response submission: FDA classifies and sets PDUFA date

Amgen Inc. today announced that the U.S. Food and Drug Administration (FDA) has evaluated the content of the Company's Complete Response submission for Prolia™ (denosumab) in the treatment of postmenopausal osteoporosis and classified it as a Class 2 resubmission. With the Class 2 designation, the FDA set a corresponding Prescription Drug User Fee Act (PDUFA) action date of July 25, 2010.

20 Feb 2010

Emory School of Medicine to enroll nearly 1,140 people for Phase III clinical trial of progesterone for TBI

Researchers at 17 medical centers across the country soon will begin using the hormone progesterone to treat patients who experience traumatic brain injury (TBI). The treatment is part of a randomized, double-blind Phase III clinical trial that will enroll approximately 1,140 people over a three- to six-year period beginning in March, 2010. The trial is funded by a grant to Emory University from the National Institutes of Health.

20 Feb 2010

Benefits of wartime camaraderie extend far beyond the battlefield: Study of U.S. Civil War veterans

Veterans who served in military units characterized by a strong esprit de corps were much less likely decades later to die of a stroke or heart condition than veterans from less cohesive companies, two UCLA economists have found.

19 Feb 2010

PsychoGenics announces alliance with experimental neuropharmacology expert for specialized microdialysis services

PsychoGenics Inc. today announced the establishment of an exclusive alliance with Dr. Jan Kehr, an internationally recognized expert in experimental neuropharmacology, to provide specialized microdialysis services to complement PsychoGenics’ in vivo testing capabilities.

19 Feb 2010

BHRT for treatment of SAD in women

Patients Medical, a leading integrative and holistic medicine center in New York City, offers cutting-edge Bioidentical Hormone Replacement Therapy (BHRT) to help women transition from winter to spring when hormonal modulations are especially high. Rashmi Gulati, MD, Medical Director of Patients Medical and a trained holistic physician with the American College for Advancement of Medicine, helps women gain relief from Seasonal Affective Disorder (SAD) through individualized bioidentical hormone treatments.

19 Feb 2010

Steroids and weight loss products can accelerate hair loss, says hair loss expert

In a study due to be released next month, the world's leading hair transplant and hair loss expert Dr. Larry Shapiro will show that men and women have been losing their hair from using popular weight loss and work out products that contain whey protein isolate- and it's not just their genes that are to blame.

19 Feb 2010

Marcadia Biotech commences Phase 1 clinical trial of MAR701 for type 2 diabetes

Marcadia Biotech Inc. today announced that it has initiated a Phase 1 clinical trial of MAR701, a novel dual agonist of the incretin hormone receptors for glucagon-like peptide-1 (GLP-1) and gastric inhibitory peptide (GIP). Marcadia plans to initially develop this compound as a treatment for type 2 diabetes with once-weekly dosing. The Phase 1 trial will evaluate MAR701 in healthy volunteers at escalating dose levels.

17 Feb 2010

Soligenix' LPM oral drug delivery technology receives Hong Kong patent

Soligenix, Inc., a late-stage biotechnology company, announced today that it has received a Hong Kong patent which addresses its Lipid Polymer Micelle (LPM™) technology for the improved oral delivery of drugs. The issued Hong Kong patent, HK 1071054, entitled "Stabilized Reverse Micelle Compositions and Uses Thereof" covers lipid structures (reverse micelles) that promote the intestinal absorption of peptides and other sensitive drugs that cannot otherwise be given orally.

17 Feb 2010

Researchers discover new strategy to overcome drug resistance in breast cancer

Combining tamoxifen, the world's most prescribed breast cancer agent, with a compound found in the flowering plant feverfew may prevent initial or future resistance to the drug, say researchers at Georgetown Lombardi Comprehensive Cancer Center.

17 Feb 2010

Phase II clinical trial result of abiraterone drug shows promise for advanced prostate cancer

New results from a phase II clinical trial of the prostate cancer drug abiraterone suggest that it may help men with advanced disease who have tried standard treatments.

17 Feb 2010

Disparities in breast cancer treatment: African-American women diagnosed in later stages of disease

Cancer, the peer-reviewed international journal of the American Cancer Society, has published a study conducted by HealthCore, Inc. in its Jan. 1 edition, demonstrating disparities in breast cancer treatment between commercially insured African-American and white women.

17 Feb 2010

Protein crucial in mediating anti-inflammatory actions of nuclear lipid receptors discovered

Researchers at the Swedish medical university Karolinska Institutet have discovered a protein that is crucial in mediating the anti-inflammatory actions of nuclear lipid receptors. The findings, published in the research journal Genes & Development, link lipid metabolism and inflammation and open up new possibilities for developing treatments of metabolic diseases associated with inflammation, such as diabetes and atherosclerosis.

17 Feb 2010

First field study shows lack of exposure to morning light delays sleep in teenagers

The first field study on the impact of light on teenagers' sleeping habits finds that insufficient daily morning light exposure contributes to teenagers not getting enough sleep.

17 Feb 2010

Hormone News and Research

Further Reading

Study examines associations of different fats and subtypes of ischemic stroke in post-menopausal women

INMA researchers study the consequences iodine supplements in pregnant women

Scientists identify key mechanism of drug resistance in breast cancer patients

Depression and stress hormone levels may lead to obesity in girls

Woman's risk of heart disease intensifies during natural menopause: Study

Older diabetes patients with high stress levels are more likely to experience memory loss

Amylin Pharmaceuticals and Takeda Pharmaceutical to advance pramlintide/metreleptin combination therapy development

Amgen's Prolia Complete Response submission: FDA classifies and sets PDUFA date

Emory School of Medicine to enroll nearly 1,140 people for Phase III clinical trial of progesterone for TBI

Benefits of wartime camaraderie extend far beyond the battlefield: Study of U.S. Civil War veterans

PsychoGenics announces alliance with experimental neuropharmacology expert for specialized microdialysis services

BHRT for treatment of SAD in women

Steroids and weight loss products can accelerate hair loss, says hair loss expert

Marcadia Biotech commences Phase 1 clinical trial of MAR701 for type 2 diabetes

Soligenix' LPM oral drug delivery technology receives Hong Kong patent

Researchers discover new strategy to overcome drug resistance in breast cancer

Phase II clinical trial result of abiraterone drug shows promise for advanced prostate cancer

Disparities in breast cancer treatment: African-American women diagnosed in later stages of disease

Protein crucial in mediating anti-inflammatory actions of nuclear lipid receptors discovered

First field study shows lack of exposure to morning light delays sleep in teenagers

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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