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Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Researchers discovered that oligodendrocytes, not just neurons, produce amyloid β in Alzheimer's disease, and suppressing their activity improves disease pathology. This finding suggests new therapeutic targets for Alzheimer's treatment.

24 Jul 2024

Creating the first genetically susceptible mice for late-onset Alzheimer's

Mice don't get Alzheimer's-;and while that's good news for mice, it's a big problem for biomedical researchers seeking to understand the disease and test new treatments.

24 Jul 2024

Review highlights hidden gut-brain connection in neurological disorders

Research reveals the gut microbiota-brain axis as a critical link in understanding and treating neurological disorders through microbial interventions.

23 Jul 2024

Oligodendrocytes identified as key source of amyloid beta in Alzheimer's disease

Oligodendrocytes are an important source of amyloid beta (Aβ) and play a key role in promoting neuronal dysfunction in Alzheimer's disease (AD), according to a study published July 23, 2024 in the open-access journal PLOS Biology by Rikesh Rajani and Marc Aurel Busche from the UK Dementia Research Institute at University College London, and colleagues.

23 Jul 2024

Is air pollutant exposure during pregnancy associated with infant cerebral palsy risk?

The association between prenatal exposure to ambient air pollution during the pregnancy and the risk of cerebral palsy in the infant.

12 Jul 2024

Archaeal, fungal, viral, as well as bacterial, functional makers for autism spectrum disorder in children

Researchers investigated the associations between multikingdom gut microbiome components and functional markers with autism spectrum disorder through metagenomic sequencing of children's fecal samples.

11 Jul 2024

How may cannabis affect neurodevelopment when exposed in the womb?

Researchers investigated whether prenatal cannabis exposure is related to variations in brain development, which may partially mitigate the relationship between PCE and increased psychopathology throughout early adolescence.

9 Jul 2024

Pandemic stress leads to surge in ADHD diagnoses and medication use in Finland

Study reveals a significant rise in ADHD diagnoses and medication use in Finland during the COVID-19 pandemic, highlighting the pandemic's impact on mental health recognition, especially among young women and older adults.

3 Jul 2024

Family history of mental health disorders linked to developmental outcomes in siblings of autistic children

Researchers studied the impact of family history of neurodevelopmental and neuropsychiatric disorders on developmental outcomes in siblings of children with autism, highlighting significant associations with various phenotypic traits.

24 Jun 2024

Impact of family history on developmental outcomes in siblings of children with autism

Children who have an older sibling with autism spectrum disorder (autism) are at greater risk of developmental vulnerabilities if they also have other relatives with neurodevelopmental or psychiatric conditions, according to a new study from the Yale Child Study Center.

19 Jun 2024

Study highlights benefits of ADHD medications for pregnant patients with opioid use disorder

Opioid overdoses for pregnant patients are at an all-time high in the United States, even as overall numbers are improving.

13 Jun 2024

‘I try to stay strong’: Mom struggles to get diagnosis for son’s developmental problems

Four-year-old Ahmeir Diaz-Thornton couldn't sit still in class and rarely ate his lunch. While his preschool classmates spoke in perfect sentences, Ahmeir had trouble pronouncing words.

12 Jun 2024

New program aims to reduce the strain on caregivers of children with ADHD

Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterized by elevated levels of inattention, impulsivity, and hyperactivity that can impair academic and social functioning.

4 Jun 2024

Household chaos and sleep hygiene impact sleep quality in teens with ADHD

A new study to be presented at the SLEEP 2024 annual meeting found that household chaos and sleep hygiene are important factors in the relationship between sleep quality and ADHD symptoms in teens.

31 May 2024

Study offers insight into early developmental risk factors for ADHD

Several early developmental factors are associated with an increased risk of ADHD during childhood and adolescence.

29 May 2024

Emotional dysregulation identified as core symptom of ADHD

Cambridge scientists have shown that problems regulating emotions – which can manifest as depression, anxiety and explosive outbursts – may be a core symptom of attention deficit hyperactivity disorder (ADHD).

22 May 2024

4 ways vaccine skeptics mislead you on measles and more

Measles is on the rise in the United States. So far this year, the number of cases is about 17 times what it was, on average, during the same period in each of the four years before, according to the Centers for Disease Control and Prevention.

22 May 2024

Physical activity can be beneficial for cognitive development of children with ADHD

Attention Deficit Hyperactivity Disorder can impact many common childhood milestones and cognitive processes, such as decision-making, inhibitory control, language development, and goal-setting. Studies by University of Rhode Island kinesiology Assistant Professor Nicole Logan have shown that physical activity can be beneficial for the development of such cognitive processes, particularly in children who may have room to improve in those areas.

16 May 2024

Study uncovers sex differences in brain responses to low sexual desire

Study reveals that women with Hypoactive Sexual Desire Disorder (HDSS) show a "top-down" brain inhibition pattern, while men do not, suggesting significant sexual dimorphism in brain responses to sexual stimuli.