Hypercholesterolemia News and Research

RSS
Hypercholesterolemia is a condition characterized by very high levels of cholesterol in the blood. Cholesterol is a waxy, fat-like substance that is produced in the body and obtained from foods that come from animals (particularly egg yolks, meat, poultry, fish, and dairy products). The body needs this substance to build cell membranes, make certain hormones, and produce compounds that aid in fat digestion. Too much cholesterol, however, increases a person's risk of developing heart disease.

People with hypercholesterolemia have a high risk of developing a form of heart disease called coronary artery disease. This condition occurs when excess cholesterol in the bloodstream is deposited in the walls of blood vessels, particularly in the arteries that supply blood to the heart (coronary arteries). The abnormal buildup of cholesterol forms clumps (plaque) that narrow and harden artery walls. As the clumps get bigger, they can clog the arteries and restrict the flow of blood to the heart. The buildup of plaque in coronary arteries causes a form of chest pain called angina and greatly increases a person's risk of having a heart attack.

Inherited forms of hypercholesterolemia can also cause health problems related to the buildup of excess cholesterol in other tissues. If cholesterol accumulates in tendons, it causes characteristic growths called tendon xanthomas. These growths most often affect the Achilles tendons and tendons in the hands and fingers. Yellowish cholesterol deposits under the skin of the eyelids are known as xanthelasmata. Cholesterol can also accumulate at the edges of the clear, front surface of the eye (the cornea), leading to a gray-colored ring called an arcus cornealis.
What is the association between renal function and regular coffee consumption?

What is the association between renal function and regular coffee consumption?

Emory doctors join forces with the Family Heart Foundation to help patients with familial hypercholesterolemia

Emory doctors join forces with the Family Heart Foundation to help patients with familial hypercholesterolemia

Metabolomic study of genetic regulation of biochemical individuality

Metabolomic study of genetic regulation of biochemical individuality

New analysis finds significant disparities in the treatment of familial hypercholesterolemia

New analysis finds significant disparities in the treatment of familial hypercholesterolemia

Erectile function at three months after COVID-19 recovery

Erectile function at three months after COVID-19 recovery

ACC publishes guidance on the role of nonstatin therapies for lowering LDL-C levels

ACC publishes guidance on the role of nonstatin therapies for lowering LDL-C levels

RINVOQ® (upadacitinib) Approved by European Commission as an Oral Treatment for Adults with Active Non-Radiographic Axial Spondyloarthritis

RINVOQ® (upadacitinib) Approved by European Commission as an Oral Treatment for Adults with Active Non-Radiographic Axial Spondyloarthritis

Most familial hypercholesterolemia patients remain undiagnosed, analysis reveals

Most familial hypercholesterolemia patients remain undiagnosed, analysis reveals

Geisinger researchers receive two grants to study risk factors linked with familial hypercholesterolemia

Geisinger researchers receive two grants to study risk factors linked with familial hypercholesterolemia

What is the optimal LDL cholesterol level for patients with cardiovascular diseases?

What is the optimal LDL cholesterol level for patients with cardiovascular diseases?

Health screening and genetic tests may help detect people who carry a gene for familial hypercholesterolemia

Health screening and genetic tests may help detect people who carry a gene for familial hypercholesterolemia

Hypertensive disorders of pregnancy linked to CVD risk later in life

Hypertensive disorders of pregnancy linked to CVD risk later in life

Parents should know their children's cholesterol levels, expert says

Parents should know their children's cholesterol levels, expert says

More is better than less when it comes to physical activity and cardiovascular disease

More is better than less when it comes to physical activity and cardiovascular disease

Worsening brain function linked to deep anesthesia during surgery

Worsening brain function linked to deep anesthesia during surgery

Phenome study reveals alternate associations with SARS-CoV-2 risk loci

Phenome study reveals alternate associations with SARS-CoV-2 risk loci

BioIVT to highlight the use of SCHH model to investigate drug-drug interaction of bempedoic acid

BioIVT to highlight the use of SCHH model to investigate drug-drug interaction of bempedoic acid

Women with familial hypercholesterolemia miss out on active treatment because of pregnancy

Women with familial hypercholesterolemia miss out on active treatment because of pregnancy

Daily walnut consumption lowers LDL cholesterol levels and may promote cardiovascular health

Daily walnut consumption lowers LDL cholesterol levels and may promote cardiovascular health

AHA special issue focuses on health disparities among racial, ethnic communities

AHA special issue focuses on health disparities among racial, ethnic communities