Hyperglycemia News and Research

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Hyperglycemia occurs when you have a higher than usual level of glucose in your blood. This can happen shortly after you have eaten a big meal and is not a problem if your glucose level returns to normal. Cells remove glucose from the blood in response toinsulin. If your pancreas doesn't make enough insulin, glucose can't enter the cells and remains in the blood. Blood glucose levels can also get too high if cells areunable to respond to insulin properly (insulinresistance). Without glucose, your cells are unable to make energy and can't function properly.

Higher maternal sugar levels increases risk of childhood obesity

Treating diabetes during pregnancy can break the link between gestational diabetes and childhood obesity, according to a Kaiser Permanente study featured in the September issue of Diabetes Care.

28 Aug 2007

Alogliptin for type 2 diabetes shows promise in early trial

Alogliptin, a highly selective dipeptidyl peptidase-IV (DPP-4) inhibitor under investigation for the treatment of type 2 diabetes, demonstrated efficacy in reducing glucose levels throughout the day, in an early phase clinical study.

26 Jun 2007

Hyperglycemia and adverse pregnancy outcome study (HAPO)

Gestational diabetes may place a much higher percentage of pregnant women -- and their unborn babies -- at risk for adverse outcomes than previously believed, according to a major international study presented at the American Diabetes Association's 67th Annual Scientific Sessions.

23 Jun 2007

NAFLD fibrosis score helps predict advanced fibrosis in patients with nonalcoholic fatty liver disease

Certain routine demographic, clinical, and laboratory values can be used to identify advanced fibrosis in patients with nonalcoholic fatty liver disease (NAFLD).

4 Apr 2007

Effect of hydrocortisone treatment modality on glycemic control in patients with septic shock

Changing how critically ill patients are treated with hydrocortisone could reduce hyperglycemia.

18 Feb 2007

Researchers identify risk factors for healthy survival in men

Avoiding health risk factors in midlife such as smoking, being overweight, excessive drinking and hypertension is associated with a longer and healthier life in men, according to a study in the November 15 issue of JAMA: The Journal of the American Medical Association, a theme issue on men's health.

14 Nov 2006

1 in 5 youth with diabetes has heart risk

With the epidemic of obesity in the United States leading to a greater incidence of diabetes among youth, a new study highlights why Americans cannot afford to ignore this dangerous trend: One in five youth with diabetes has already developed two or more additional risk factors for premature heart disease.

27 Jul 2006

Procedure cures some diabetic mice, but not in the way previously reported

Researchers attempting to reproduce a controversial 2003 mouse experiment suggestive of a cure for type 1 diabetes have found evidence that the experimental procedure does eliminate diabetic symptoms in a small fraction of the mice exposed to it.

28 Mar 2006

Researchers transplant insulin-producing neonatal porcine islet cells into monkeys

A team of researchers from the University of Alberta, the Yerkes National Primate Research Center of Emory University and the Emory Transplant Center has successfully transplanted insulin-producing neonatal porcine islet cells into monkeys, a procedure the researchers say represents a promising intermediate solution to the critical supply problem in clinical islet cell transplantation.

27 Feb 2006

Diabetics warned against using antibiotic drug Tequin

The Food and Drug Administration in the U.S. have issued strong warnings concerning the use of the antibiotic drug Tequin.

16 Feb 2006

Association of aprotinin with reduced glucose levels during CABG surgery

An anesthesiology research team at Columbia University Medical Center have completed the first human study to show that aprotinin, a protease inhibitor, was associated with lower blood glucose levels during coronary artery bypass graft (CABG) surgery.

25 Oct 2005

Metabolic syndrome (MetS) in Europe

Previously, several different definitions for the metabolic syndrome (MetS) had been proposed and used by researchers. This resulted in confusion about the frequency of the MetS and its relationship with mortality.

5 Sep 2005

Over-supply of blood sugar could be a major cause of erectile dysfunction in diabetic men

Researchers have found that one particular simple sugar, present in increased levels in diabetics, interferes with the chain of events needed to achieve and maintain erection and can lead to permanent penile impairment over time.

9 Aug 2005

Study findings offer hope of identifying new at-risk population for pancreatic cancer

According to a study published in the American Gastroenterological Association (AGA) journal Gastroenterology, 1 in 120 people newly diagnosed with diabetes age 50 and older have a higher risk of developing pancreatic cancer - a risk that is eight times more than expected for the general population.

2 Aug 2005

Ranbaxy receives tentative approval to manufacture and market Glimepiride tablets

Indian drug manufacturer, Ranbaxy Pharmaceuticals has tentative approval from the U.S. Food and Drug Administration to manufacture and market Glimepiride Tablets, 3 mg and 6 mg.

28 Jul 2005

New compound ruboxistaurin may decrease vision loss in diabete

A multicenter international study chaired by a Joslin Diabetes Center investigator and reported in the July issue of the American Diabetes Association's journal Diabetes brings hopeful news to the 18 million people in the United States -- and millions more worldwide -- with type 1 or type 2 diabetes.

15 Jul 2005

Study reveals benefits of using insulin earlier

Results of an all-Canadian study announced June 13 at an international diabetes congress demonstrate that patients with type 2 diabetes can safely achieve target blood sugar (glycemic) levels faster and more frequently when insulin glargine (a basal, long-acting insulin) is added to therapy, versus using oral agents alone.

14 Jun 2005

Link between PKC enzyme and kidney disease in diabetes confirmed

Researchers at Joslin Diabetes Center have investigated PKC-beta - a critical enzyme implicated in the devastating complications of type 1 and type 2 diabetes - for more than two decades.

12 Jun 2005

Link between hyperglycemia (high blood glucose), overexpression of PKC-beta 2 and kidney disease

Scientists at Joslin Diabetes Center have investigated PKC-beta -- a critical enzyme implicated in the devastating complications of type 1 and type 2 diabetes -- for more than two decades.

10 Jun 2005

Metabolic syndrome prevalent in heart attack patients

Nearly half of heart attack patients also met criteria for metabolic syndrome, putting them at a higher risk for development of heart failure, according to an article in the May 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

23 May 2005