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Sheep model may help address fertility problems in women

A Texas A&M AgriLife study with sheep may soon help address fertility problems in women, if it can discover ways to break the chain of generational transfer of polycystic ovary syndrome, PCOS -- one of the most common infertility disorders.

23 Feb 2021

Drugs for benign prostatic hyperplasia associated with increased risk of cardiac failure

Widely used medications for benign prostatic hyperplasia (BPH) - also known as enlarged prostate - may be associated with a small, but significant increase in the probability of developing heart failure, suggests a study in The Journal of Urology, Official Journal of the American Urological Association.

22 Feb 2021

Gut microbe may play a role in the development of breast cancers

A microbe found in the colon and commonly associated with the development of colitis and colon cancer also may play a role in the development of some breast cancers, according to new research from investigators with the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

6 Jan 2021

Computers could use subtle facial features to recognize congenital adrenal hyperplasia

Congenital adrenal hyperplasia (CAH) is a disorder that affects the adrenal gland's ability to release hormones that regulate the body's response to stress and illness.

18 Nov 2020

AI can help recognize individuals with congenital adrenal hyperplasia based on facial images

Researchers at the VISTA Center (Vision, Image, Speech and Text Analytics) at the USC Viterbi Information Sciences Institutealong with scholars at the Keck School of Medicine of USC and Children's Hospital Los Angeles have discovered strong correlations between facial morphology and congenital adrenal hyperplasia (CAH), a life-threatening genetic condition of the adrenal glands and one of the most common forms of adrenal insufficiency in children.

18 Nov 2020

Goblet cells are prime target for SARS-CoV-2, study finds

A recent study reports that in the airway of patients with chronic obstructive pulmonary disease (COPD), a type of airway epithelial cell – called a goblet cell – presents a prime target for the virus and plays a vital role in promoting viral replication in this tissue.

16 Nov 2020

New evidence shows link between finasteride and suicidality

In the last decade, concerns have emerged around finasteride, a drug used for treating male-pattern baldness and prostate gland enlargement.

11 Nov 2020

Study shows ultrasound treatment can destroy cancer cells without surgery

Focusing ultrasound energy on a target site in the body to generate heat can burn and destroy the tissue in the site without a surgical procedure.

27 Oct 2020

Researchers report the discovery of innate immune signaling pathway in fibroblasts

Vanderbilt University researchers have reported the counterintuitive discovery that certain chemotherapeutic agents used to treat tumors can have the opposite effect of tissue overgrowth in normal, intact mammary glands, epidermis and hair follicles.

16 Oct 2020

SARS-CoV-2 spike protein triggers cell signaling pathways in lung vascular cells

A new study published on the preprint server bioRxiv in October 2020 shows that vascular cells in the lung tissue begin to secrete signaling growth factors when exposed to just the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), without the rest of the viral components.

14 Oct 2020

Lung tissue in fatal COVID-19 shows broad cell tropism and extensive damage

In a recent preprint paper published on the medRxiv server, researchers demonstrated their investigation of fatal COVID-19 patients to assess infection in various cell types and the extent of damage it caused to the lung tissues.

30 Sep 2020

Vitamin D deficiency during early development can influence metabolic health

Using a zebrafish model, researchers from North Carolina State University have found that vitamin D deficiency during early development can disrupt the metabolic balance between growth and fat accumulation.

29 Sep 2020

Rabbits susceptible to SARS-CoV-2: Red flag for potential virus reservoir

A new study by scientists in the Netherlands and published on the preprint server bioRxiv* in August 2020 shows that the severe acute respiratory coronavirus-2 (SARS-CoV-2) can infect rabbits, which opens the door for possible circulation in rabbit farms and another potential source of animal to human SARS-CoV-2 infection. This finding calls for urgent research on the prevalence of the virus in farmed rabbits.

30 Aug 2020

ARDS may not be the primary lung iInjury in COVID-19

A new Italian study published on the preprint server medRxiv in August 2020 shows that this may not be an adequate explanation, since ARDS is a nonspecific diagnosis. Instead, they say, antemortem lung biopsy shows a “Covid pattern” of acute lung injury, which could guide the application of therapeutics.

16 Aug 2020

Mouse model of fatal COVID-19 developed for vaccine and drug testing

Now, a new study published on the preprint server bioRxiv in July 2020 presents an engineered transgenic mouse that reproduces the functional and clinical characteristics of severe human SARS-CoV-2 infection.

21 Jul 2020

Fasting-mimicking diet along with hormone therapy could help treat breast cancer

A USC-led team of scientists has found that a fasting-mimicking diet combined with hormone therapy has the potential to help treat breast cancer, according to newly published animal studies and small clinical trials in humans.

21 Jul 2020

Genomic sequencing to provide precision medicine for aromatase deficiency

An international team of scientists from Switzerland Spain, has studied the genetic basis of aromatase deficiency, a rare metabolic disorder that prevents the production of estrogens in humans, according to new research in JCEM.

30 Jun 2020

Smoking increases ACE2 protein in the lungs which may promote COVID-19 infection

Previous data from COVID-19 patients suggests that cigarette smokers are more likely to have health complications.

18 May 2020

Giant Madeiran squill likely to have accumulated antibiotics from contaminated soil

A previous study has shown that a type of squill growing in Madeira produces a chemical compound that may be useful as a medicinal drug.

5 Apr 2020

Coronavirus pathology findings shows how the disease affects the body

Coronavirus disease (COVID-19) is spreading rapidly across the globe. Since COVID-19 is a new disease, scientists are racing to determine the nature of the virus and how it affects the human body. Now, a team of scientists, have shed light on how the virus affects the respiratory tract. The study provides essential information and descriptions of the early phase pathology of COVID-19 infection.

1 Mar 2020