Hypersensitivity News and Research

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Hypersensitivity is an exaggerated response by the immune system to a drug or other substance.

Optically controlled local heat-pulse method manipulates temperature in cells

A team of researchers led by Osaka University finds that mutant variants of the calcium channel protein RyR1 are hypersensitive to heat, which creates a positive feedback loop of calcium release and leads to malignant hyperthermia

8 Aug 2022

Research reveals increase in prescriptions of specialized infant formula

New research published in Clinical and Experimental Allergy reveals that prescriptions of specialized infant formula have increased in recent years in England, Norway, and Australia, with rates over 10-fold what would be expected for the number of children with milk allergies.

7 Jul 2022

The effect of immunization with bivalent oral poliovirus vaccine on the incidence of COVID-19

Researchers evaluated the impact of the OPV on the incidence of COVID-19.

23 Jun 2022

Study uncovers novel treatment for chromophobe renal cell carcinoma

Chromophobe renal cell carcinoma (ChRCC) is a rare form of kidney cancer for which there are currently no proven treatments for metastatic or unresectable disease.

20 Jun 2022

Evidence-based study shows how hypnotherapy provides positive outcomes for IBS patients

It is common that Hong Kong people might have experiences of disordered defecation with unknown reason, such as diarrhea and constipation. It is also easy to observe that abdominal discomforts often come along with stress. Emotion disturbance and stress might affect our intestinal functions.

14 Jun 2022

Discovery could lead to more effective treatment for chronic, pathological pain

The world has changed since 1664, when French philosopher and scientist Rene Descartes first claimed the brain was responsible for feeling the sensation of pain.

9 Jun 2022

Safety and efficacy of tixagevimab–cilgavimab in preventing severe COVID

In a recent study published in the Lancet, researchers evaluated the safety and efficacy of tixagevimab–cilgavimab, a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal antibody (mAb) combination in patients with mild to moderate coronavirus disease 2019 (COVID-19).

8 Jun 2022

Targeted dietary measures can reduce the symptom burden in allergic reactions, trial shows

Micronutrient deficiencies can promote inflammation and render the immune system particularly sensitive to allergenic substances.

8 Jun 2022

Evaluating tixagevimab plus cilgavimab against SARS-CoV-2

Researchers assessed the neutralizing activity against SARS-CoV-2 Omicron variant after tixagevimab plus cilgavimab (T+C) administration.

30 May 2022

Effectiveness of Acceptance Commitment Therapy for autistic individuals has been investigated

A doctoral thesis at Karolinska Institutet in Sweden has investigated whether Acceptance Commitment Therapy (ACT) can be used for individuals with Autism Spectrum Disorder.

18 May 2022

Researchers report widespread prevalence of reactive and acute inflammatory CNS microvasculopathy in 36 COVID-19 brain autopsies

A new study has focused on the microcirculatory factors associated with neurological complications of COVID-19.

10 May 2022

Animal study provides insights into how COVID-19 can lead to long-term pain

A new animal study has provided important insights into how COVID-19 SARS-CoV-2 -; the virus responsible for COVID-19 -; can lead to long-term pain.

4 Apr 2022

Myocarditis and pericarditis in COVID-19 vaccine recipients

A new study provides valuable evidence towards this end, using surveillance data to provide the best estimates of these outcomes.

6 Mar 2022

Convalescent plasma therapy shows no significant impact on COVID-19 recovery and outcomes

Researchers conduct a multi-center study involving hospitalized COVID-19 patients to gather information on the rationale use of convalescent plasma.

3 Mar 2022

Australian bull ants' venom component exploits a pain pathway in mammals

Australian bull ants have evolved a venom molecule perfectly tuned to target one of their predators – the echidna – that also could have implications for people with long-term pain, University of Queensland researchers say.

2 Mar 2022

Cow's milk protein can trigger inflammation in multiple sclerosis sufferers

Multiple sclerosis sufferers often complain of more severe disease symptoms after consuming dairy products. Researchers at the Universities of Bonn and Erlangen-Nuremberg have now found a possible cause for this.

1 Mar 2022

History of iodinated contrast media hypersensitivity linked to MRI contrast risk

People with a history of allergic-like reactions to iodinated contrast media, which is used in a variety of X-ray-based procedures, such as CT and angiography, are susceptible to similar reactions from commonly used MRI contrast agents, according to a large, eight-year study published in the journal Radiology.

22 Feb 2022

Assessing potential allergic reactions in COVID-19 vaccinated patients

Researchers analyze suspected reactions in patients vaccinated with the first and/or second dose of SARS-CoV-2 vaccines.

13 Feb 2022

Study finds abnormal link between autonomic and central nervous systems in patients with generalized anxiety disorder

Researchers at the Laureate Institute for Brain Research (LIBR) in Tulsa, Okla., have identified an abnormal link between the autonomic and central nervous systems, specifically via communication between the heart and part of the brain's frontal cortex, in women with generalized anxiety disorder (GAD).

2 Feb 2022

Vaccine hypersensitivity in children

A new paper published in Pediatric Allergy and Immunity provides a useful overview of such reactions in relation to pediatric vaccines.

31 Jan 2022