Hypersensitivity News and Research

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Hypersensitivity is an exaggerated response by the immune system to a drug or other substance.

New study questions the perception that autistic individuals experience less pain

People with autism have normal pain thresholds but increased sensitivity to painful stimuli, concludes a study in PAIN, the official publication of the International Association for the Study of Pain.

30 Nov 2022

Flavonoids with potential to fight allergies and inflammation

In a recent study published in the Biomedicine & Pharmacotherapy journal, researchers explored the anti-allergic and anti-inflammatory properties of flavonoids.

28 Nov 2022

Two studies reveal insights into how the spinal cord and brainstem contribute to sense of touch

The sense of touch is essential to almost everything we do, from routine tasks at home to navigating unfamiliar terrains that may conceal dangers.

23 Nov 2022

FDA approves first-ever type 1 diabetes delaying drug Tzield (teplizumab-mzwv)

On November 17, 2022, the US Food and Drug Administration (FDA) approved a pathbreaking new drug called Tzield. This injectable formulation contains a combination of two drugs that could push back the onset of type 1 diabetes (T1D) in adults at stage 3 and children aged eight years or more at stage 2.

20 Nov 2022

Children exposed to air pollution in early years more likely to develop food allergies

A new research paper explores associations between food allergies and pre- or post-natal exposure to pollutants in the air, thus paving the way for future studies on the potential sensitization of the gut by exposure of the skin or airway to pollutants, in addition to the alimentary route.

7 Nov 2022

Study uses pluripotent stem cell models to investigate stress response in PTSD patients

Stem cell-derived neurons from combat veterans with post-traumatic stress disorder (PTSD) react differently to a stress hormone than those from veterans without PTSD, a finding that could provide insights into how genetics can make someone more susceptible to developing PTSD following trauma exposure.

20 Oct 2022

Study reveals why viral infections are less frequent but more severe in individuals with Down syndrome

Individuals with Down syndrome have less-frequent viral infections, but when present, these infections lead to more severe disease.

14 Oct 2022

The compositional and functional diversity of the gut fungal microbiome

Researchers assessed the role of gut bacterial microbiome assembly and the gut mycobiome in relation to health, pathology, and clinical applications.

30 Sep 2022

Debunking ‘man flu’

Researchers debunk man flu based on a review of available evidence.

28 Sep 2022

New guideline for the evaluation and testing of patients with penicillin allergies

A new guideline published in Clinical & Experimental Allergy will help clinicians evaluate and test patients for potential penicillin allergies.

21 Sep 2022

Daily multivitamin improves cognitive function in seniors

In a recent study published in the journal Alzheimer's & Dementia, researchers in the United States investigated whether daily administration of a cocoa extract (CE, comprising 500 mg flavanols, including 80 mg epicatechins, 50 mg/day theobromine (50 mg/day), and 15mg/day caffeine) and/or an MVM (multivitamin-mineral) for three years protected cognitive functions among older men and women.

18 Sep 2022

Motorcycle helmet protects riders by filtering harmful emissions

A motorcycle helmet that filters out harmful emissions from the air is protecting riders in New Delhi and other Indian cities that rank among the most polluted in the world.

26 Aug 2022

Optically controlled local heat-pulse method manipulates temperature in cells

A team of researchers led by Osaka University finds that mutant variants of the calcium channel protein RyR1 are hypersensitive to heat, which creates a positive feedback loop of calcium release and leads to malignant hyperthermia

8 Aug 2022

Research reveals increase in prescriptions of specialized infant formula

New research published in Clinical and Experimental Allergy reveals that prescriptions of specialized infant formula have increased in recent years in England, Norway, and Australia, with rates over 10-fold what would be expected for the number of children with milk allergies.

7 Jul 2022

The effect of immunization with bivalent oral poliovirus vaccine on the incidence of COVID-19

Researchers evaluated the impact of the OPV on the incidence of COVID-19.

23 Jun 2022

Study uncovers novel treatment for chromophobe renal cell carcinoma

Chromophobe renal cell carcinoma (ChRCC) is a rare form of kidney cancer for which there are currently no proven treatments for metastatic or unresectable disease.

20 Jun 2022

Evidence-based study shows how hypnotherapy provides positive outcomes for IBS patients

It is common that Hong Kong people might have experiences of disordered defecation with unknown reason, such as diarrhea and constipation. It is also easy to observe that abdominal discomforts often come along with stress. Emotion disturbance and stress might affect our intestinal functions.

14 Jun 2022

Discovery could lead to more effective treatment for chronic, pathological pain

The world has changed since 1664, when French philosopher and scientist Rene Descartes first claimed the brain was responsible for feeling the sensation of pain.

9 Jun 2022

Safety and efficacy of tixagevimab–cilgavimab in preventing severe COVID

In a recent study published in the Lancet, researchers evaluated the safety and efficacy of tixagevimab–cilgavimab, a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal antibody (mAb) combination in patients with mild to moderate coronavirus disease 2019 (COVID-19).

8 Jun 2022

Targeted dietary measures can reduce the symptom burden in allergic reactions, trial shows

Micronutrient deficiencies can promote inflammation and render the immune system particularly sensitive to allergenic substances.