Hypersensitivity News and Research

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Hypersensitivity is an exaggerated response by the immune system to a drug or other substance.

FDA approves drug for treatment of neuromyelitis optica spectrum disorder

The U.S. Food and Drug Administration has approved Enspryng (satralizumab-mwge) for the treatment of neuromyelitis optica spectrum disorder (NMOSD) in adults with a particular antibody - patients who are anti-aquaporin-4 or AQP4 antibody-positive.

17 Aug 2020

FDA approves opioid agonist for management of moderate to severe acute pain in adults

Today, the U.S. Food and Drug Administration approved Olinvyk (oliceridine), an opioid agonist for the management of moderate to severe acute pain in adults, where the pain is severe enough to require an intravenous opioid and for whom alternative treatments are inadequate.

9 Aug 2020

Neuroscientists map brain's sensory gatekeeper in unprecedented detail

Many people with autism experience sensory hypersensitivity, attention deficits, and sleep disruption. One brain region that has been implicated in these symptoms is the thalamic reticular nucleus (TRN), which is believed to act as a gatekeeper for sensory information flowing to the cortex.

22 Jul 2020

Eating black raspberries may reduce skin inflammation associated with allergies, study shows

Eating black raspberries might reduce inflammation associated with skin allergies, a new study indicates.

2 Jul 2020

Researchers investigate the effects of isolation in zebrafish

Over the past few months at least half of the world's population has been affected by some form of lockdown due to COVID-19, and many of us are experiencing the impact of social isolation.

10 Jun 2020

Using functional MRI to demonstrate neural suppression in autism

According to the National Autism Association, people with autism spectrum disorder (ASD) may experience sensory hypersensitivity.

29 May 2020

Frog brain discovery may pave the way for repairing birth defects in humans

A team of researchers from Tufts University, Universitat de Valencia, and Harvard University has discovered that the brains of developing frog embryos damaged by nicotine exposure can be repaired by using “ionoceuticals” that can help in the recovery of bioelectric patterns in the embryo.

28 May 2020

New animal model for COVID-19

As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to ravage the world, scientists are frantically searching for a vaccine or new drug that will effectively counter the lethal effects of the virus that leads to COVID-19 disease.

19 May 2020

Study: Gut microbiomes of astronauts become more diverse in space rather than less

We all carry around our own microbiome, a world of microorganisms that live on our skin and in our bodies, playing important roles in maintaining health as we interact with the rest of the world.

15 May 2020

ACR releases new guideline for management of gout

Today, the American College of Rheumatology released the 2020 Guideline for the Management of Gout.

11 May 2020

UMB and UMD fund cross-campus research projects

The University of Maryland, Baltimore (UMB) and the University of Maryland, College Park (UMD) are funding new cross-campus research projects as part of a new joint program that seeks to solve big health care challenges through joint research that draws on the institutions world leading expertise in medicine and artificial intelligence.

23 Apr 2020

Study reveals the neural basis of sensory hypersensitivity in people with autism

Many people with autism spectrum disorders are highly sensitive to light, noise, and other sensory input. A new study in mice reveals a neural circuit that appears to underlie this hypersensitivity, offering a possible strategy for developing new treatments.

2 Mar 2020

Light touch on the skin loses its pleasure in people with migraine

A recent study published in the journal Cephalalgia, the official journal of the International Headache Society, builds on the sensorial characteristics of migraine patients.

14 Feb 2020

Pulmonary imaging key to diagnosing vaping-related lung damage

In 2019, the emergence of mysterious lung disease in the United States has sparked global health attention. Now named as the e-cigarette, or vaping, product use–associated lung injury (EVALI), the disease causes lung damage, which is a serious and sometimes fatal complication of vaping.

28 Jan 2020

Type of upper airway bacteria could influence asthma severity

A new study raises the possibility of modulating asthma symptoms via the bacteria that commonly live in the upper airway. The work, which was published on December 16, 2019, in the journal Nature Communications, shows that in children who have mild to moderate asthma, the microbiome of the upper airway could determine how severe the symptoms are.

16 Dec 2019

Study highlights overlooked relationship between exercise and migraine

A recent study published in the journal Cephalalgia, the official journal of the International Headache Society, highlights an overlooked relationship between migraine and exercise.

12 Dec 2019

Michigan dermatologists honored for diagnosing rare condition

The American Academy of Dermatology has honored board-certified dermatologists Steven Daveluy, MD, FAAD, and Benjamin Workman, MD, FAAD, as Patient Care Heroes for their teamwork with oncologists to diagnose a rare condition affecting just one in a million patients, known as drug-induced hypersensitivity syndrome.

4 Dec 2019

New vaccine against bovine TB

A new study published in the journal Scientific Reports says that for the first time a vaccine has been created against bovine tuberculosis that can be given without affecting the ability to diagnose tuberculosis later using the PPD skin test.

28 Nov 2019

New drug 'ubrogepant' may work for migraine

A new study published in the November 19, 2019 issue of JAMA shows that a newly developed small molecule drug called ubrogepant may successfully fight migraine at doses of 25 and 50 mg, with pain relief at 2 hours with both doses, while the most troublesome symptom of migraine was held off at 2 hours post-dose with the 50 mg dose. This may help millions of migraine patients to achieve pain relief and function better.

19 Nov 2019

Mysterious feather duvet lung disease nearly kills a man

A soft pillow and a warm duvet are all you need to have a soothing and relaxing sleep, especially during the frigid season. However, a man from the United Kingdom nearly died because of a mysterious illness related to a duvet. It was later found out by doctors that the culprit for his lung disease is his newly-bought feather duvet.

19 Nov 2019