Hypothalamus News and Research

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The Hypothalamus is the area of the brain that controls body temperature, hunger, and thirst.

Machine learning approach helps study human hypothalamus at the single-cell level

Human brain organoids are remarkable platforms for modeling features of human brain development and diseases.

11 May 2021

Study focuses on understanding the origin of neuronal diversity

A mechanistic understanding of brain development requires a systematic survey of neural progenitor cell types, their lineage specification and maturation of postmitotic neurons.

21 Apr 2021

Study identifies how SARS-CoV-2 enters and infects the brain

A recent preclinical study led by Anja Kipar of the University of Zurich and the University of Liverpool found evidence of the virus infecting and eventually provoking cell death in microglia and immune cells — but not neurons. The viral-induced apoptosis in these brain cells may explain why some long-haulers experience ‘brain fog’ months after recovery.

21 Apr 2021

Two extremes of female sexual behavior may be controlled by the same brain region

In many species, including humans and mice, the fluctuating levels of the hormones progesterone and estrogen determine whether the female is fertile or not. And in the case of mice, whether she's sexually receptive or not.

20 Apr 2021

Light therapy offers a safe, cost-effective alternative for treatment of neurodegenerative diseases

A lot about the human brain and its intricacies continue to remain a mystery. With the advancement of neurobiology, the pathogenesis of several neurodegenerative diseases (ND) has been uncovered to a certain extent along with molecular targets around which current therapies revolve.

19 Apr 2021

Mother's stress levels during conception could be a determinant of fetal sex

A study carried out by scientists from the University of Granada has revealed that women who experience stress both before becoming pregnant and during conception are almost twice as likely to have a girl as a boy.

6 Apr 2021

Research looks at inflammatory nature of lipid nanoparticle component in mRNA vaccines

In a recent bioRxiv preprint research paper, Botond Z. Igyártó and colleagues from Thomas Jefferson University demonstrated the inflammatory nature of the lipid nanoparticles (LNPs).

15 Mar 2021

New approach could treat infertility caused by abnormal GnRH secretion

Reports suggest that at least 25% of ovarian disorders are due to dysfunction of the brain mechanism in the hypothalamus that controls the gonadotropin-releasing hormone (GnRH), which is a molecule that governs the reproductive function in men and women by regulating the release of a range of reproductive hormones into the body, particularly gonadotropins, from the pituitary gland, which is located underneath the brain.

12 Mar 2021

Study identifies new therapeutic targets for treatment of obesity and type 2 diabetes

The GIP receptor in the central nervous system plays a crucial role in the regulation of body weight and food intake.

10 Feb 2021

Study: Brain hormones could improve metabolism and fight obesity

A mitochondrial hormone expressed by cells deep in the brain appears to play a role in improving metabolism and fighting off obesity, according to a new study in mice.

3 Feb 2021

Study sheds new light on the role of MLL4 gene in Kabuki syndrome

Scientists have known for years that mutations in the MLL4 gene can cause Kabuki syndrome, a rare developmental disorder.

11 Jan 2021

Study shows long-term consequences of peripubertal stress

This work has investigated the long-term consequences of stress experienced at this critical period of life in rodents, in collaboration with the Behavioural Genetics laboratory at the Brain and Mind Institute of the Federal Polytechnic School of Lausanne (Switzerland), led by the Spanish researcher Carmen Sandi.

14 Dec 2020

Study finds potential target for the treatment of anxiety and obsessive-compulsive disorder

Anxiety disorders and obsessive-compulsive disorder (OCD) are disabling psychiatric conditions and the major contributors to global burden of nonfatal illness.

2 Dec 2020

Researchers identify a neural pathway that links circadian clock, stress, and wakefulness

A Nagoya University-led research team in Japan has found a new neural pathway that links the circadian clock, stress, and wakefulness in mammals.

27 Nov 2020

Hormone that suppresses food intake could be used as potential treatment for obesity

A hormone that can suppress food intake and increase the feeling of fullness in mice has shown similar results in humans and non-human primates, says a new study published today in eLife.

24 Nov 2020

COVID-19 potentially has negative impacts on male fertility

A review recently published in the Journal of Medical Virology has discussed some of the effects that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – may have on male fertility.

22 Nov 2020

Study: Novel drug may treat reproductive health problems in women

A drug that acts via the natural 'kisspeptin' hormone system in the body has the potential to treat reproductive health problems in women, according to a new study.

17 Nov 2020

Innate, diet-induced changes to the brain's reward system may predispose some mice to overeat

A combination of innate differences and diet-induced changes to the reward system may predispose some mice to overeat, according to research recently published in JNeurosci.

12 Nov 2020

Researchers identify distinct link between autism and brain cell abnormalities

Johns Hopkins Medicine researchers report that new experiments with genetically engineered mice have found clear connections among a range of autism types and abnormalities in brain cells whose chemical output forges platonic (non-sexual) feelings of love and sociability.

30 Oct 2020

Social threat can change a specific brain region

Our brains are wired to protect us from threats. For social animals like humans, threats often come from other members of our own species when there is conflict over food, mates, or territory.