Ibuprofen News and Research

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Ibuprofen is a drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

Researchers develop powerful method to solve structures of small molecules

Small molecules -- from naturally occurring metabolites and hormones to synthetic medicines and pesticides -- can have big effects on living things. But for scientists to understand how the molecules work and how to design beneficial ones, they need to know the precise arrangement of atoms and chemical bonds.

9 Nov 2018

Inflammation can cause sleep and shiftwork-type disorders

Inflammation, which is the root cause of autoimmune disorders including arthritis, Type 1 diabetes, irritable bowel syndrome and Crohn's disease, has unexpected effects on body clock function and can lead to sleep and shiftwork-type disorders, a new Northwestern Medicine study in mice found.

31 Oct 2018

New method for making mirrored forms of molecules

One of the biggest challenges facing synthetic chemists is how to make molecules of only a particular "handedness." Molecules can come in two shapes that mirror each other, just like our left and right hands.

26 Oct 2018

Study: Nurse-led care can be more successful in managing gout

Providing nurse-led care for people suffering with the painful, long-term condition gout could lead to an increase in the number of patients sticking to a beneficial treatment plan, a clinical trial has revealed.

19 Oct 2018

Inflammatory proteins in the colon increase in parallel with increasing weight, study shows

Studies in mice have demonstrated that obesity-induced inflammation contributes to the risk of colorectal cancer, but evidence in humans has been scarce.

11 Oct 2018

Low-dose aspirin use associated with reduced ovarian cancer risk

Taking a low-dose aspirin daily may help women lower their risk of developing ovarian cancer. A new study co-led by Moffitt Cancer Center found that women who reported taking a low-dose aspirin every day had a 23 percent lower risk of ovarian cancer compared to nonaspirin users.

4 Oct 2018

New statement provides detailed overview of how to diagnose, treat resistant hypertension

Resistant hypertension affects 12 percent to15 percent of patients treated for high blood pressure according to a new scientific statement from the American Heart Association.

14 Sep 2018

BIDMC researchers identify risk factors that increase risk of prolonged opioid use

Current research demonstrates that patients' exposure to opioids following medical care has contributed to the nationwide addiction epidemic.

1 Aug 2018

Study shows spillover effect of evidence-based opioid prescribing for major procedures

To curb the use of opioids after major elective operations and prevent these pain relievers from falling into the wrong hands, surgeons at the University of Michigan developed prescribing recommendations based on published medical evidence for one operation, gall bladder removal, and then discovered a spillover effect that led them to prescribe roughly 10,000 fewer pills for other major operations, according to study results appearing as an "article in press" on the website of the Journal of the American College of Surgeons ahead of print.

27 Jul 2018

Doling out pain pills post-surgery: An ingrown toenail not the same as a bypass

What's the right painkiller prescription to send home with a patient after gallbladder surgery or a cesarean section?

22 Jun 2018

Prescription drugs that could raise risk of depression

Researchers are working towards understanding how use of certain regularly used prescription drugs could be raising the risk of getting depression. The study was published yesterday in the latest issue of the Journal of the American Medical Association.

13 Jun 2018

Study finds molecular handle that chikungunya virus uses to enter into cells and cause arthritis

Chikungunya virus is a growing threat to the United States and other regions of the world as the mosquito that carries the virus expands its reach. Telltale symptoms of chikungunya infection are fever and joint pain that last about a week.

17 May 2018

Nonsteroidal anti-inflammatory drug ranked to be most effective in treating knee OA

An estimated 45 percent of people are at risk of developing knee osteoarthritis (OA) in their lifetime. According to a network meta-analysis research article published in the May 1, 2018 issue of the Journal of the American Academy of Orthopaedic Surgeons, the nonsteroidal anti-inflammatory drug naproxen was ranked most effective in individual knee OA treatment for improving both pain and function, and is considered a relatively safe and low-cost treatment method.

2 May 2018

Non-aspirin NSAID use linked to shorter survival in patients with metastatic renal cell carcinoma

Ibuprofen, aspirin, and other non-steroidal anti-inflammatory medications are among the most commonly utilized medications in the United States. Primarily for treating pain, inflammation, and preventing cardiovascular disease, NSAIDs' promising anti-cancer properties have been highlighted by a growing body of data in recent years.

2 May 2018

New drug for migraine in the pipeline

According to a pilot study results released yesterday (17th of April 2018), a new drug may help provide relief to people with migraine that is unsuccessfully treated with the currently available drugs.

18 Apr 2018

NSAIDs alone or with acetaminophen better than opioids at easing dental pain

Opioids are not among the most effective-or longest lasting- options available for relief from acute dental pain, a new examination of the results from more than 460 published studies has found.

17 Apr 2018

Painkiller use during pregnancy could affect unborn child's fertility in later life

Taking painkillers during pregnancy could affect the fertility of the unborn child in later life, research suggests.

16 Apr 2018

Daily regimen of ibuprofen can ward off Alzheimer's disease, say neuroscientists

A Vancouver-based research team led by Canada's most cited neuroscientist, Dr. Patrick McGeer, has successfully carried out studies suggesting that, if started early enough, a daily regimen of the non-prescription NSAID (nonsteroidal anti-inflammatory drug) ibuprofen can prevent the onset of Alzheimer's disease.

26 Mar 2018

Campus voices: Should student health centers offer abortion pills?

Forty-five years after Roe v. Wade made abortions legal, a growing number of states — and the federal government — are restricting access to them.

12 Mar 2018

Ibuprofen intake could be leading to male infertility

According a new study that appeared this week in the journal Proceedings of the National Academy of Sciences, simple pain reliever, Ibuprofen, could be having a problematic effect on the testes of young men. Ibuprofen is taken almost routinely by young athletes for injuries and pain.

9 Jan 2018