Ibuprofen News and Research

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Ibuprofen is a drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

Researchers develop highly sensitive cell model to study complex effects of anti-inflammatory drugs

Drugs such as ibuprofen or aspirin that relieve pain and lower fever are among the most frequently used drugs worldwide. They are used above all for the treatment of inflammatory reactions. However, in spite of their indisputable effectiveness and frequent use, we do not yet fully understand the underlying mechanisms of these drugs.

23 Feb 2019

The American Heart Association issues new reference toolkit for healthcare providers

With nearly half of American adults having elevated blood pressure, it’s important for everyone to understand that some common habits may affect blood pressure, making the condition more difficult to control.

21 Feb 2019

Research finds steep rise in self-poisonings among young people

Self-harm from self-poisoning in children and adolescents is not only increasing but starting at a younger age, finds new research by University of Sydney and the NSW Poisons Information Centre.

20 Feb 2019

Patients taking anti-depressants more likely to develop gastrointestinal bleeding

Patients taking anti-depressant medications classified as selective serotonin reuptake inhibitors are 40 percent more likely to develop severe gastrointestinal bleeding, particularly when they also use common over-the-counter pain relievers, according to a research review in the Journal of the American Osteopathic Association.

31 Jan 2019

Regular use of common pain relief medicines improves survival for head and neck cancer patients

Regular use of a common type of medication, such as aspirin and ibuprofen, significantly improves survival for a third or more patients with head and neck cancer, a new study led by UC San Francisco has found.

25 Jan 2019

Opioid drugs often overprescribed to children for pain relief, say CHOP surgeons

Opioid drugs prescribed to children for pain relief after a typical pediatric orthopaedic procedure may be significantly overprescribed, according to a new study by researchers at Children's Hospital of Philadelphia (CHOP).

17 Jan 2019

Insured but still in debt: 5 jobs pulling in $100k a year no match for medical bills

Robert and Tiffany Cano of San Tan Valley, Ariz., have a new marriage, a new house and a 10-month-old son, Brody, who is delighted by his ability to blow raspberries.

28 Dec 2018

Virginia Tech and UC San Diego researchers team up to develop nonopioid drug for chronic pain

Researchers from the Virginia Tech School of Neuroscience are teaming with the University of California San Diego and the U.S. National Institutes of Health to develop a drug -- now in its earliest stages -- that can treat certain types of chronic pain without the addictive consequences of opioids.

12 Dec 2018

Inhibition of prostaglandin E2 enhances ability to combat infectious colitis

The treatment of intestinal infections caused by some strains of the bacterium Escherichia coli, present in unsanitized or contaminated foods, may have a new ally.

15 Nov 2018

Researchers develop powerful method to solve structures of small molecules

Small molecules -- from naturally occurring metabolites and hormones to synthetic medicines and pesticides -- can have big effects on living things. But for scientists to understand how the molecules work and how to design beneficial ones, they need to know the precise arrangement of atoms and chemical bonds.

9 Nov 2018

Inflammation can cause sleep and shiftwork-type disorders

Inflammation, which is the root cause of autoimmune disorders including arthritis, Type 1 diabetes, irritable bowel syndrome and Crohn's disease, has unexpected effects on body clock function and can lead to sleep and shiftwork-type disorders, a new Northwestern Medicine study in mice found.

31 Oct 2018

New method for making mirrored forms of molecules

One of the biggest challenges facing synthetic chemists is how to make molecules of only a particular "handedness." Molecules can come in two shapes that mirror each other, just like our left and right hands.

26 Oct 2018

Study: Nurse-led care can be more successful in managing gout

Providing nurse-led care for people suffering with the painful, long-term condition gout could lead to an increase in the number of patients sticking to a beneficial treatment plan, a clinical trial has revealed.

19 Oct 2018

Inflammatory proteins in the colon increase in parallel with increasing weight, study shows

Studies in mice have demonstrated that obesity-induced inflammation contributes to the risk of colorectal cancer, but evidence in humans has been scarce.

11 Oct 2018

Low-dose aspirin use associated with reduced ovarian cancer risk

Taking a low-dose aspirin daily may help women lower their risk of developing ovarian cancer. A new study co-led by Moffitt Cancer Center found that women who reported taking a low-dose aspirin every day had a 23 percent lower risk of ovarian cancer compared to nonaspirin users.

4 Oct 2018

New statement provides detailed overview of how to diagnose, treat resistant hypertension

Resistant hypertension affects 12 percent to15 percent of patients treated for high blood pressure according to a new scientific statement from the American Heart Association.

14 Sep 2018

BIDMC researchers identify risk factors that increase risk of prolonged opioid use

Current research demonstrates that patients' exposure to opioids following medical care has contributed to the nationwide addiction epidemic.

1 Aug 2018

Study shows spillover effect of evidence-based opioid prescribing for major procedures

To curb the use of opioids after major elective operations and prevent these pain relievers from falling into the wrong hands, surgeons at the University of Michigan developed prescribing recommendations based on published medical evidence for one operation, gall bladder removal, and then discovered a spillover effect that led them to prescribe roughly 10,000 fewer pills for other major operations, according to study results appearing as an "article in press" on the website of the Journal of the American College of Surgeons ahead of print.

27 Jul 2018

Doling out pain pills post-surgery: An ingrown toenail not the same as a bypass

What's the right painkiller prescription to send home with a patient after gallbladder surgery or a cesarean section?

22 Jun 2018

Prescription drugs that could raise risk of depression

Researchers are working towards understanding how use of certain regularly used prescription drugs could be raising the risk of getting depression. The study was published yesterday in the latest issue of the Journal of the American Medical Association.

13 Jun 2018