Immune Response News and Research

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Study finds overall pattern of commonality between Huntington's and Parkinson's

A new study strongly suggests that the brains of people who have died of Huntington's disease (HD) and Parkinson's disease (PD) show a similar response to a lifetime of neurodegeneration, despite being two very distinct diseases.

12 Jan 2018

Researchers discover new weapon to combat tuberculosis

Tuberculosis (TB), an infectious disease which attacks the lungs, claims someone's life every 20 seconds and 1.5 million lives worldwide every year.

11 Jan 2018

New study shows how the immune system regulates gut fungal population

Immune cells that process food and bacterial antigens in the intestines control the intestinal population of fungi, according to a new study from Weill Cornell Medicine scientists.

11 Jan 2018

Patients with desmoplastic melanoma respond well to immunotherapy

Desmoplastic melanoma is a rare subtype of melanoma that is commonly found on sun-exposed areas, such as the head and neck, and usually seen in older patients.

11 Jan 2018

Scientists use artificial intelligence to create new ‘ImmunoMap’

Johns Hopkins scientists have used a form of artificial intelligence to create a map that compares types of cellular receptors, the chemical "antennas" on the surface of immune system T-cells.

8 Jan 2018

Newly identified biomarkers predict cancer patient’s response to immunotherapy

Researchers at the University of Zurich have identified biomarkers in the blood that make it possible to predict whether cancer patients will respond positively to immunotherapy.

8 Jan 2018

Specific bacteria in the intestines can improve response rate to cancer immunotherapy

In the Jan. 5, 2018 issue of Science, researchers from the University of Chicago Medicine show that specific strains of commensal bacteria – the swarms of microorganisms naturally dwelling in the intestines – can improve the response rate to immunotherapy for patients being treated for advanced melanoma.

5 Jan 2018

Macrophage nanosponges offer promising solution for effectively managing sepsis

A team of researchers at the University of California San Diego has developed macrophage "nanosponges" that can safely absorb and remove molecules from the bloodstream that are known to trigger sepsis.

4 Jan 2018

Gene therapy with CAR T-cells could create long-term immunity from HIV

Through gene therapy, researchers engineered blood-forming stem cells (hematopoietic stem/progenitor cells, or HSPCs) to carry chimeric antigen receptor (CAR) genes to make cells that can detect and destroy HIV-infected cells.

29 Dec 2017

Nanobiotix receives FDA approval for first immuno-oncology trial

NANOBIOTIX, a late clinical-stage nanomedicine company pioneering new approaches to the treatment of cancer, today announced the U.S. Food and Drug Administration has approved its Investigational New Drug Application for NBTXR3, a first-in-class nanoparticle designed for direct injection into cancerous tumors, activated by stereotactic ablative radiotherapy (SABR) and administered in combination with an anti-PD1 antibody (nivolumab or pembrolizumab).

26 Dec 2017

Scientists discover five new regions of the genome that increase asthma risk

An international study led by scientists from Inserm and Paris Diderot Universit, the University of Chicago, the National Heart and Lung Institute and the University of Colorado Anschutz Medical Campus together with researchers of the Trans-National Asthma Genetics Consortium has discovered five new regions of the genome that increase the risk of asthma.

22 Dec 2017

Higher ‘mutational burden’ of tumors predicts success rate with cancer immunotherapies

The "mutational burden," or the number of mutations present in a tumor's DNA, is a good predictor of whether that cancer type will respond to a class of cancer immunotherapy drugs known as checkpoint inhibitors, a new study led by Johns Hopkins Kimmel Cancer Center researchers shows.

21 Dec 2017

Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells

A new study from The Wistar Institute revealed the mechanism implicated in the defective function of tumor-associated dendritic cells (DCs), a specialized type of immune cells that expose the antigens on their surface to activate the T cells.

15 Dec 2017

Researchers examine link between tumor mutational burden and response to immune checkpoint therapy

Predicting how patients will respond to anti-cancer therapies can be vital in informing clinical decisions and improving treatment outcome.

15 Dec 2017

Mosquito-infected monkeys may provide better understanding of Zika transmission routes

Monkeys who catch Zika virus through bites from infected mosquitoes develop infections that look like human Zika cases, and may help researchers understand the many ways Zika can be transmitted.

14 Dec 2017

Study: Living Lyme disease bacteria found months after antibiotic treatment

Bay Area Lyme Foundation, a leading sponsor of Lyme disease research in the US, today announced results of two papers published in the peer-reviewed journals PLOS ONE and American Journal of Pathology, that seem to support claims of lingering symptoms reported by many patients who have already received antibiotic treatment for the disease.

14 Dec 2017

Immune Response News and Research

Study finds overall pattern of commonality between Huntington's and Parkinson's

Researchers discover new weapon to combat tuberculosis

New study shows how the immune system regulates gut fungal population

Patients with desmoplastic melanoma respond well to immunotherapy

Scientists use artificial intelligence to create new ‘ImmunoMap’

Newly identified biomarkers predict cancer patient’s response to immunotherapy

Specific bacteria in the intestines can improve response rate to cancer immunotherapy

Macrophage nanosponges offer promising solution for effectively managing sepsis

Gene therapy with CAR T-cells could create long-term immunity from HIV

Nanobiotix receives FDA approval for first immuno-oncology trial

Scientists discover five new regions of the genome that increase asthma risk

Higher ‘mutational burden’ of tumors predicts success rate with cancer immunotherapies

Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells

Researchers examine link between tumor mutational burden and response to immune checkpoint therapy

Mosquito-infected monkeys may provide better understanding of Zika transmission routes

Study: Living Lyme disease bacteria found months after antibiotic treatment

Researchers suggest role for MKL1 protein in development of inflammatory bowel disease

Cellular self-digestion process plays role in development of autoimmune diseases

Single-dose oral vaccine could be effective tool in controlling cholera outbreaks

Study reveals how the body clock and time of day may influence autoimmune conditions

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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