Immune Response News and Research

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Early-life infections may be risk factor for developmental disorders later in life

The Zika virus now active in numerous countries, and the severe birth defects associated with it, makes it clear that infection in pregnant women can have immediate and devastating effects on the developing baby.

19 Aug 2016

New clinical trial to examine safety of checkpoint inhibitor in pediatric cancer patients

In an innovative, first-in-pediatrics study, available only at Children's Hospital Los Angeles, researchers will be enrolling children between 1 and 18 years of age who have certain types of relapsed or treatment-resistant cancer.

18 Aug 2016

Mice study finds new approach to halt cycle of chronic inflammation in lupus

Molecules that scavenge debris from dying cells appear to halt the cycle of chronic inflammation in lupus, while also enhancing the body's ability to combat flu, according to Duke Health studies in mice.

17 Aug 2016

ECTRIMS previews important sessions ahead of world’s largest annual congress of multiple sclerosis

The European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) previews the key sessions ahead of its annual congress – a dedicated platform to promote and enhance research in Multiple Sclerosis. The 32nd edition of the world’s largest congress of multiple sclerosis will take place in London from 14 – 17 September 2016.

17 Aug 2016

Drugs designed to target nervous system could control inflammation in the gut, study shows

There's a reason it's called a gut feeling. The brain and the gut are connected by intricate neural networks that signal hunger and satiety, love and fear, even safety and danger. These networks employ myriad chemical signals that include dopamine, a powerful neurotransmitter most famous for its role in reward and addiction.

11 Aug 2016

Antioxidant compound could be effective to combat immune rejection after islet transplantation

A team of researchers has found that doses of bilirubin help provide suppression of the immune response following islet transplantation in mouse models.

11 Aug 2016

Hygiene hypothesis: a misleading misnomer? An interview with Professor Sally Bloomfield

Professor Strachan first proposed the hygiene hypothesis back in 1989. Reviewing the evidence, he suggested that one of the causes of the recent rapid rise in allergic diseases in children was lack of exposure to childhood infections

11 Aug 2016

Analysis of biopsies during early treatment predicts patient’s response to melanoma immunotherapy

Immune response measured in tumor biopsies during the course of early treatment predicts which melanoma patients will benefit from specific immune checkpoint blockade drugs, researchers at The University of Texas MD Anderson Cancer Center report in the journal Cancer Discovery.

11 Aug 2016

Commonly used anti-inflammatory drug shows potential to treat Alzheimer's disease

A research project has shown that an experimental model of Alzheimer's disease can be successfully treated with a commonly used anti-inflammatory drug.

11 Aug 2016

RNA silencing technique developed by spinoff from UM-Madison effective in battling hepatitis B

A method for "silencing" RNA that emerged from a University of Wisconsin-Madison spinoff company is in clinical trials in Europe, Asia and the United States against hepatitis B, an infection that can destroy the liver.

11 Aug 2016

New technology uses natural nano-scale lipid transport system to deliver drugs straight to bloodstream

For years scientists and dieticians have argued over the health benefits of dietary fat. Research published this week, however, shows that piggybacking onto natural fat absorption pathways can dramatically enhance the utility of some drugs.

10 Aug 2016

Scientists improve potential weapon to fight against autoimmune disorders

With a trick of engineering, scientists at the Gladstone Institutes improved a potential weapon against inflammation and autoimmune disorders. Their work could one day benefit patients who suffer from inflammatory bowel disease or organ transplant rejection.

9 Aug 2016

Researchers uncover new preventative way to battle against Ascaris roundworm infection

Scientists working out of Trinity College Dublin, Maynooth University, and Queen Mary University of London have unearthed a potential new preventative option to combat Ascaris roundworm infection.

8 Aug 2016

Immunotherapy innovations in oncology: an interview with Robert LaCaze

The body’s immune system is an excellent weapon against many diseases. For more than 100 years, immunology and immunotherapy have played an ever-increasing role in the understanding and treatment of cancer.

8 Aug 2016

UM SOM selected as study site for human safety trial of new Zika vaccine

As world leaders increasingly recognize the Zika virus as an international public health threat, the Center for Vaccine Development at the University of Maryland School of Medicine's Institute for Global Health has been chosen as one of three study sites in a human safety trial of a new Zika vaccine.

7 Aug 2016

Amish farm environment protects children from asthma by shaping immune system

By probing the differences between two farming communities—the Amish of Indiana and the Hutterites of South Dakota—an interdisciplinary team of researchers found that specific aspects of the Amish environment are associated with changes to immune cells that appear to protect children from developing asthma.

4 Aug 2016

People with lymphatic filariasis more likely to acquire HIV infection, study shows

People infected with a parasitic worm called Wuchereria bancrofti in areas where HIV is endemic may be more likely to acquire HIV than people who are not infected with the worm, according to a new study in southwest Tanzania, published in The Lancet.

4 Aug 2016

NIH launches clinical trial of experimental vaccine candidate for preventing Zika virus infection

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has launched a clinical trial of a vaccine candidate intended to prevent Zika virus infection.

3 Aug 2016

Researchers identify crucial innate immunity role for gene linked to ARC syndrome in children

UT Southwestern Medical Center researchers have found an important innate immunity role for a gene linked to a rare, fatal syndrome in children. Their study has implications for a much more common disease: tuberculosis.

2 Aug 2016

Vaccines unsuccessful in protecting obese mice against influenza infections, study finds

A study led by St. Jude Children's Research Hospital found that obese mice are not protected against influenza infections by vaccines that include adjuvants, raising concerns about vaccine effectiveness in obese humans who are known to be at an increased risk for severe flu. The findings appear today in the scientific journal mBio.

2 Aug 2016

Immune Response News and Research

Early-life infections may be risk factor for developmental disorders later in life

New clinical trial to examine safety of checkpoint inhibitor in pediatric cancer patients

Mice study finds new approach to halt cycle of chronic inflammation in lupus

ECTRIMS previews important sessions ahead of world’s largest annual congress of multiple sclerosis

Drugs designed to target nervous system could control inflammation in the gut, study shows

Antioxidant compound could be effective to combat immune rejection after islet transplantation

Hygiene hypothesis: a misleading misnomer? An interview with Professor Sally Bloomfield

Analysis of biopsies during early treatment predicts patient’s response to melanoma immunotherapy

Commonly used anti-inflammatory drug shows potential to treat Alzheimer's disease

RNA silencing technique developed by spinoff from UM-Madison effective in battling hepatitis B

New technology uses natural nano-scale lipid transport system to deliver drugs straight to bloodstream

Scientists improve potential weapon to fight against autoimmune disorders

Researchers uncover new preventative way to battle against Ascaris roundworm infection

Immunotherapy innovations in oncology: an interview with Robert LaCaze

UM SOM selected as study site for human safety trial of new Zika vaccine

Amish farm environment protects children from asthma by shaping immune system

People with lymphatic filariasis more likely to acquire HIV infection, study shows

NIH launches clinical trial of experimental vaccine candidate for preventing Zika virus infection

Researchers identify crucial innate immunity role for gene linked to ARC syndrome in children

Vaccines unsuccessful in protecting obese mice against influenza infections, study finds

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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