Immune Response News and Research

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Stimuvax investigational lung cancer vaccine phase III study starts

Merck KGaA today announced that the first patient has been enrolled in its global Phase III clinical study, START (Stimulating Targeted Antigenic Responses To NSCLC), assessing the efficacy and safety of Stimuvax (BLP25 liposome vaccine) as a potential treatment for patients with unresectable stage III non-small cell lung cancer (NSCLC).

26 Feb 2007

New bird flu vaccine not such a sure bet

According to the Food and Drug Administration (FDA) in the U.S., in clinical trials the nation's first bird flu vaccine is not as effective as was initially expected.

26 Feb 2007

Chemotherapy drug bortezomib packs a one-two punch

Cancer can be wily, and those who treat the disease have amassed a wide array of weapons with which to fight it and kill tumors.

20 Feb 2007

Promising results on avian influenza vaccines

Experts meeting this week at the World Health Organization (WHO) on advances in pandemic influenza vaccine development reported encouraging progress.

18 Feb 2007

Nasal spray vaccine gives kids more protection from flu than shots

In a new study involving thousands of children across the world, a new version of the nasal spray vaccine FluMist has been found to be more effective at preventing influenza than traditional flu shots.

18 Feb 2007

South Africa starts major HIV/AIDS vaccine trial

The launch of the first large-scale study to evaluate a candidate HIV vaccine on the African continent was announced today by study collaborators in the United States and South Africa. The trial will involve up to 3,000 participants at five sites throughout South Africa and is expected to continue for four years.

11 Feb 2007

Fighting influenza with 40,000 blood samples

Four million people die every year from respiratory diseases such as viral influenza. For elderly people in particular, an infection can be dangerous. What is more, the flu vaccine is not as effective with this risk group as it is with younger people.

7 Feb 2007

Peptide vaccine fights off breast tumors with help of bacteria-mimicking agents

With the help of immune system-stimulating molecules that mimic bacterial components, researchers have used a type of cancer vaccine to both delay and prevent breast tumors in mice.

1 Feb 2007

Novel approach to synthesizing nanowires

A novel approach to synthesizing nanowires (NWs) allows their direct integration with microelectronic systems for the first time, as well as their ability to act as highly sensitive biomolecule detectors that could revolutionize biological diagnostic applications, according to a report in Nature.

31 Jan 2007

Different treatments may be needed for chronic asthma, depending on whether it results from allergies or lung infections

Researchers have now identified a particular gene that influences how severe a M. pneumoniae infection may be, which in turn suggests that a different strategy might be needed for treating asthma resulting from this and similar lung infections rather than allergies.

31 Jan 2007

Investigational treatment for cervical dysplasia

Temple University Hospital's Center For Women's Health is participating in a national study to determine the safety and effectiveness of an investigational treatment for cervical dysplasia.

30 Jan 2007

GlaxoSmithKline's new influenza vaccine accepted for review in Europe

GlaxoSmithKline has announced that its new generation H5N1 split antigen pre-pandemic influenza vaccine has been accepted for review by the Committee for Medicinal Products for Human Use (CHMP) in Europe.

29 Jan 2007

Polymer nanoparticles for immunotherapy from encapsulated tumor-associated antigens and whole tumor cells

Using a biodegradable nanoparticle as a means of delivering tumor cell debris and proteins to the immune system, investigators at Yale University have developed a promising new method for creating therapeutic anticancer vaccines.

29 Jan 2007

Possible reason for severe side-effects of Northwick Park clinical trial

A possible reason why the Northwick Park clinical trial of the drug TGN1412 caused multiple organ failure in human volunteers is revealed in research presented at a conference near Paris.

25 Jan 2007

New understanding of the hit-and-run tactics used by infectious bacteria

New research from scientists at the University of Cambridge has the potential to radically change our understanding of how infection spreads around the body and improve the methods used to control it.

22 Jan 2007

Researchers to study use of carbon monoxide in treating disease

Scientists at the University of York have won a grant of £110,000 to investigate potential uses of carbon monoxide in treating disease.

22 Jan 2007

Novavax's pandemic flu vaccines show promise

Novavax, Inc.'s novel virus-like particle (VLP) vaccines have been shown to be effective in generating protection against pandemic influenza as well as cross protection against different strains of the virus in pre-clinical studies, according to data presented at the Phacilitate Vaccine Forum.

22 Jan 2007

New approach offers hope for an effective herpes vaccine

A researcher at Montana State University has called for an innovative, new approach in developing a vaccine against genital herpes.

10 Jan 2007

Allergic reactions to insulin have declined and Continuous Subcutaneous Insulin Infusion could reduce them further

A review of published research from the University of Liege, Belgium, reveals a decline in the number of people experiencing allergic reactions to insulin. This is largely due to better purification of animal insulin and the introduction of human recombinant insulin.

8 Jan 2007

Herpes appears to play a role in bringing about Alzheimer's disease

A gene known to be a major risk factor for Alzheimer's disease puts out the welcome mat for the virus that causes cold sores, allowing the virus to be more active in the brain compared to other forms of the gene.

3 Jan 2007