Immune Response News and Research

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Mucosal IgA antibodies in the airways protect against SARS-CoV-2 infection for at least eight months

High levels of mucosal IgA antibodies in the airways protect against SARS-CoV-2 infection for at least eight months.

16 Jan 2023

What is the effectiveness of a multivalent exosome-based COVID-19 vaccine?

Researchers assessed the effectiveness of a multivalent exosome-based coronavirus disease 2019 (COVID-19) vaccine.

16 Jan 2023

Study directly links gut leakage with retinopathy severity in people with Type 1 diabetes

The leading cause of blindness in American adults is diabetic retinopathy, progressive damage to blood vessels in the light-sensitive tissue at the back of the eye.

14 Jan 2023

Scientists use paleogenomics to trace 10,000 years of human immune system evolution

Scientists from the Institut Pasteur, Université Paris Cité, the CNRS and the Collège de France have used paleogenomics to trace 10,000 years of human immune system evolution.

13 Jan 2023

The impact of early life microbial colonization and respiratory diseases on the respiratory microbiome

Researchers reviewed the impact of the interactions between the respiratory microbiota and the immune system.

13 Jan 2023

Recent findings on original antigenic sin and SARS-CoV-2

Researchers collated the findings of studies relating original antigenic sin with SARS-CoV-2 evolution.

13 Jan 2023

COVID-19 booster doses could significantly reduce the incidence of SARS-CoV-2 infection among young adults

A recent study published in the journal PLOS Medicine examined the effectiveness of booster doses of coronavirus disease 2019 (COVID-19) vaccines in protecting vaccinated young adults against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections during the dominant period of the Omicron BA.1 variant.

12 Jan 2023

New technique could overcome the delivery hurdles faced by promising mRNA therapies

A team of researchers led by The University of Texas MD Anderson Cancer Center has developed a novel delivery system for messenger RNA (mRNA) using extracellular vesicles (EVs).

12 Jan 2023

Using lipid nanoparticles and messenger RNA to treat blindness associated with rare genetic condition

Oregon State University College of Pharmacy scientists have demonstrated in animal models the possibility of using lipid nanoparticles and messenger RNA, the technology underpinning COVID-19 vaccines, to treat blindness associated with a rare genetic condition.

11 Jan 2023

Annual or biannual boosters greatly reduce the long-term risk of infection from endemic COVID-19

While COVID-19 boosters have been found to protect against infection, hospitalization, and severe illness, the waning of their protection has led to uncertainty about when it is most appropriate to get an additional booster shot.

11 Jan 2023

Rethinking next generation of improved vaccines for mucosa-replicating viruses

Vaccines that provide long-lasting protection against influenza, coronaviruses and respiratory syncytial virus (RSV) have proved exceptionally difficult to develop.

11 Jan 2023

Simple method increases the efficacy of T cell therapy by cytokine conjugation

The recent years have seen a wave of adoptive cell therapies (ACTs), a type of immunotherapy in which T cells (T cell transfer therapy) and other immune cells are obtained from patients, activated and multiplied outside the body, and infused in larger numbers back into the blood circulation to help fight cancers.

11 Jan 2023

New analysis improves the scientific community's understanding of COVID-19 immunity

A new analysis by Cedars-Sinai investigators is furthering the scientific community's understanding of COVID-19 immunity by showing that similar levels of COVID-19 antibodies are reached over an extended period of time in different population groups.

11 Jan 2023

Anticancer drugs offer new hope for treatment of sepsis

Research led by the IGC reveals how these drugs limit inflammation, positioning them as potential treatments for sepsis.

10 Jan 2023

Study describes a mechanism associated with the production of neuropathic pain

Neuropathic pain is a type of chronic pain caused by damage to the nervous system due mainly to metabolic diseases such as diabetes and arthritis, or to the side effects of some kinds of chemotherapy.

10 Jan 2023

Vaccinating against toxin produced by E. coli may protect against malnutrition and stunting

Diarrhea is no longer the killer it was in the mid-20th century, when an estimated 4.5 million children under age 5 died of it every year.

9 Jan 2023

Study uncovers molecular features responsible for the development, progression of metastatic breast cancer

A multi-institutional national study has identified unique molecular features responsible for the development and progression of metastatic breast cancer.

9 Jan 2023

Novel T cell receptor therapy shows early promise for treating solid tumors

Afamitresgene autoleucel (afami-cel; formerly ADP-A2M4), an adoptive T cell receptor (TCR) therapy targeting the MAGE-A4 cancer antigen, achieved clinically significant results for patients with multiple solid tumor types in a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

9 Jan 2023

Research suggests people on rheumatoid arthritis drugs show weaker response to SARS-CoV-2 vaccines

Researchers conducted a comparative study among a cohort of individuals on rheumatoid arthritis (RA) therapies vis-à-vis healthy controls to assess their responses to coronavirus disease 2019 (COVID-19) vaccines.

9 Jan 2023

COVID-19 vaccine potency and breadth improved by nanoparticle-conjugated adjuvants

In a recent study posted to bioRxiv*, researchers designed a nanoparticle (NP)-conjugated toll-like receptor 9 (TLR9) agonist to improve the adjuvanticity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines.

8 Jan 2023

Immune Response News and Research

Mucosal IgA antibodies in the airways protect against SARS-CoV-2 infection for at least eight months

What is the effectiveness of a multivalent exosome-based COVID-19 vaccine?

Study directly links gut leakage with retinopathy severity in people with Type 1 diabetes

Scientists use paleogenomics to trace 10,000 years of human immune system evolution

The impact of early life microbial colonization and respiratory diseases on the respiratory microbiome

Recent findings on original antigenic sin and SARS-CoV-2

COVID-19 booster doses could significantly reduce the incidence of SARS-CoV-2 infection among young adults

New technique could overcome the delivery hurdles faced by promising mRNA therapies

Using lipid nanoparticles and messenger RNA to treat blindness associated with rare genetic condition

Annual or biannual boosters greatly reduce the long-term risk of infection from endemic COVID-19

Rethinking next generation of improved vaccines for mucosa-replicating viruses

Simple method increases the efficacy of T cell therapy by cytokine conjugation

New analysis improves the scientific community's understanding of COVID-19 immunity

Anticancer drugs offer new hope for treatment of sepsis

Study describes a mechanism associated with the production of neuropathic pain

Vaccinating against toxin produced by E. coli may protect against malnutrition and stunting

Study uncovers molecular features responsible for the development, progression of metastatic breast cancer

Novel T cell receptor therapy shows early promise for treating solid tumors

Research suggests people on rheumatoid arthritis drugs show weaker response to SARS-CoV-2 vaccines

COVID-19 vaccine potency and breadth improved by nanoparticle-conjugated adjuvants

Hasret Altan-Martin

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