Immune System News and Research

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Discovery of genetic trigger for disease-fighting antibodies

A research team led by the La Jolla Institute for Allergy & Immunology has identified the specific gene which triggers the body to produce disease-fighting antibodies -- a seminal finding that clarifies the exact molecular steps taken by the body to mount an antibody defense against viruses and other pathogens.

17 Jul 2009

Turmeric spice and vitamin D may help clear amyloid plaques found in Alzheimer's

UCLA scientists and colleagues from UC Riverside and the Human BioMolecular Research Institute have found that a form of vitamin D, together with a chemical found in turmeric spice called curcumin, may help stimulate the immune system to clear the brain of amyloid beta, which forms the plaques considered the hallmark of Alzheimer's disease.

15 Jul 2009

Schering-Plough expands Vicriviroc study in treatment-naive patients with HIV

Schering-Plough Corporation has announced that it has extended to stage two an ongoing Phase II clinical study with vicriviroc, its investigational CCR5 antagonist, for use in first-line therapy of adult treatment-naive HIV-infected patients with R5-type virus only. In this study, vicriviroc is being evaluated in a novel nucleoside-sparing regimen that is designed to provide additional options for treatment-naive patients in a once daily regimen, while preserving other drug classes for subsequent lines of treatment.

15 Jul 2009

Skin cancer researchers throw new light on tumour growth

Three researchers from the Dermatology Research Foundation at the University of Sydney have identified a compound produced by certain fatal skin cancer tumours, providing new hope for developing treatments.

14 Jul 2009

Researchers map how staph infections alter immune system

Infectious disease specialists at UT Southwestern Medical Center have mapped the gene profiles of children with severe Staphylococcus aureus infections, providing crucial insight into how the human immune system is programmed to respond to this pathogen and opening new doors for improved therapeutic interventions.

14 Jul 2009

Medical use for waste television screens

Waste material from discarded televisions could be recycled and used in medicine, according to new research by scientists at the University of York.

13 Jul 2009

Studies provide clues to how Alzheimer’s disease develops and may be treated

The anti-inflammatory drug indomethacin could hold promise as a treatment for Alzheimer's disease, says a Saint Louis University doctor and researcher.

12 Jul 2009

One secret to how tuberculosis resists the host immune system

Mycobacterium tuberculosis is arguably the world's most successful infectious agent because it knows how to avoid elimination by slowing its own growth to a crawl. Now, a report in the July 10 issue of the journal Cell, a Cell Press publication, offers new insight into the bugs' talent for meager living.

9 Jul 2009

Innovative study brings us closer to an explanation for Crohn's disease

Twenty-five per cent of Crohn's disease patients have a mutation in what is called the NOD2 gene, but it is not precisely known how this mutation influences the disease.

9 Jul 2009

Iron supplements for preventing or treating anemia among children in malaria-endemic areas

Iron supplements do not increase the likelihood of contracting malaria and should not be withheld from children at risk of the disease, despite World Health Organisation (WHO) guidelines to the contrary, a new review by Cochrane Researchers suggests.

7 Jul 2009

Brain's immune system may cause chronic seizures

Chronic seizures caused by traumatic head injuries may result from chemicals released by the brain's immune system attempting to repair the injured site, according to a study led by the University of Colorado at Boulder.

6 Jul 2009

Future of organ transplantation - microscopic beads that create "designer " immune cells

The future of organ transplantation could include microscopic beads that create "designer" immune cells to help patients tolerate their new organ, Medical College of Georgia researchers say.

6 Jul 2009

Potential new target for acute myeloid leukemia

Dr. John Dick, Senior Scientist at the Ontario Cancer Institute, the research arm of Princess Margaret Hospital, co-led a multinational team that has developed the first leukemia therapy that targets a protein, CD123, on the surface of cancer stem cells that drive acute myeloid leukemia (AML), which is an aggressive disease with a poor outcome.

6 Jul 2009

Researchers using microRNA to identify aggressive melanoma

Research at the University of Leicester will be breaking new ground in the search for a simple blood test that could tell whether a patient with melanoma has the condition in an aggressive form.

30 Jun 2009

Lifespan of HIV-infected cells might be shorter than previously anticipated

Dutch-sponsored researcher Christian Althaus has used mathematical models to demonstrate that cells infected with HIV could live even shorter than was thought until now. If infected cells have a shorter lifespan then this increases the chances of the virus escaping the attention of the immune system.

30 Jun 2009

Periodontitis and atherosclerotic cardiovascular disease

Additional research is called for and patients with moderate to severe periodontitis should receive evaluation and possible treatment to reduce their risk of atherosclerotic cardiovascular disease (CVD), according to a special consensus paper by editors of The American Journal of Cardiology and Journal of Peridontology in the July 1, 2009 issue of The American Journal of Cardiology, published by Elsevier.

30 Jun 2009

Peptic ulcer bacterium alters the body's defence system

Helicobacter pylori survives in the body by manipulating important immune system cells. This is shown in a thesis from the Sahlgrenska Academy, University of Gothenburg, Sweden. The discovery may lead to new treatments against the common peptic ulcer bacterium.

30 Jun 2009

Epigenetic modulation at birth - altered DNA-methylation in white blood cells after Caesarean section

Swedish researchers have discovered that babies born by Caesarean section experience changes to the DNA pool in their white blood cells, which could be connected to altered stress levels during this method of delivery, according to the July issue of Acta Paediatrica.

30 Jun 2009

Discovery of new trigger for chronic inflammation in rheumatoid arthritis

A signal molecule made by the human body that triggers the immune system into action may be important in rheumatoid arthritis, according to new research published today in Nature Medicine. The authors of the study, from Imperial College London, say that if scientists could block this signal, it may be possible to develop more effective arthritis treatments.

29 Jun 2009

Gene expression differences could bring better classification and treatment of juvenile arthritis

Scientists have discovered gene expression differences that could lead to better ways to classify, predict outcome, and treat juvenile idiopathic arthritis (JIA). Eventually such findings could enable doctors to target more aggressive treatment to children at risk of more severe arthritis, while those likely to have milder disease could be spared the stronger treatments that carry a greater risk of side effects. The researchers were supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health.

29 Jun 2009