Immune System News and Research

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Cellular crosstalk between mother and offspring is more complex than expected

Scientists have known for decades that pregnancy requires a mother's body to adjust so that her immune system does not attack the growing fetus as if it were a hostile foreign invader.

22 Sep 2023

Peptide vaccine targets H3K27M mutation in midline gliomas, shows promise in early trials

Tumor vaccines can help the body fight cancer. These vaccines alert the patient's immune system to proteins that are carrying cancer-typical alterations.

22 Sep 2023

Placental disease: A key contributor to unexplained pregnancy loss

New study in Reproductive Sciences identifies placental diseases as the likely cause for 99% of unexplained pregnancy losses, shedding light on miscarriages and stillbirths. The research suggests that identifying specific placental pathologies could lead to more preventative measures.

21 Sep 2023

Manipulating mitochondrial electron flow enhances immune response, reduces tumor growth

Immunotherapy, which uses the body's own immune system to fight cancer, is an effective treatment option, yet many patients do not respond to it.

21 Sep 2023

Compound found in hops can combat metabolic syndrome by reducing Oscillibacter population

Researchers have shown in a mouse model and lab cultures that a compound derived from hops reduces the abundance of a gut bacterium associated with metabolic syndrome.

21 Sep 2023

Study offers new insight into immune cells critical to successful vaccination against SARS-CoV-2

A study has revealed new details about a key population of immune system cells critical to successful vaccination against the pandemic virus, SARS-CoV-2.

21 Sep 2023

Could a genetic biomarker predict your risk for severe food allergies?

Researchers at Ann & Robert H. Lurie Children's Hospital of Chicago have identified a genetic biomarker, α-tryptase, that may predict the severity of food allergy reactions. This discovery opens the door for new treatment strategies and offers a way to distinguish patients at risk for severe reactions.

21 Sep 2023

New trial of a preventive HIV vaccine candidate begins in the United States and South Africa

A trial of a preventive HIV vaccine candidate has begun enrollment in the United States and South Africa.

20 Sep 2023

Mount Sinai secures $6.2 million grant to expand the Cohen Center for Recovery From Complex Chronic Illnesses

Mount Sinai's Department of Rehabilitation and Human Performance has announced a $6.2 million grant from the Steven & Alexandra Cohen Foundation.

20 Sep 2023

Scientists develop Australia’s first-of-its-kind next-gen mpox diagnostic tool

In a collaborative study published in The Lancet Microbe, the team of scientists, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute) and WEHI (Walter and Eliza Hall Institute of Medical Research), revealed MPXV-CRISPR – a powerful diagnostic tool capable of detecting MPXV in clinical samples with acute precision and at a faster rate than any other method, thanks to the power of CRISPR technology.

20 Sep 2023

New near-infrared activated photo-oxidants kill cancer cells without oxygen

A research team led by scientists from City University of Hong Kong (CityU) has achieved a significant breakthrough by inventing a new class of near-infrared-activated photo-oxidants that can effectively kill cancer cells without requiring oxygen.

20 Sep 2023

Flagellin immunization protects mice from detrimental effects of dietary emulsifiers

In a new study, mice whose immune systems were trained against the microbial protein flagellin did not experience the usual detrimental effects of ingesting food additive emulsifiers, pointing to a potential new way to combat various chronic inflammatory diseases.

20 Sep 2023

Early treatment with convalescent plasma may reduce risk of long COVID

Findings from a nationwide, multicenter study led by Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health suggest that patients with COVID-19 have less chance of developing post-COVID conditions -; commonly known as long COVID -; if they receive early treatment with plasma from convalescent (recovered) COVID patients that contain antibodies against SARS-CoV-2, the virus that causes COVID-19.

20 Sep 2023

AI-based tool can assess pathology slides to identify valuable features of clear cell renal cell carcinoma

A team of Dana-Farber researchers has identified a potential new way to assess clinically valuable features of clear cell renal cell carcinoma (ccRCC), a form of kidney cancer, using image processing with deep learning.

20 Sep 2023

Transforming postpartum depression treatment with neurosteroids

A new study in Neuropsychopharmacology delves into the mechanisms of action of brexanolone, the first FDA-approved, rapid-acting antidepressant specifically for postpartum depression (PPD). The research highlights brexanolone's potential anti-inflammatory effects and its impact on GABAA receptors, offering insights into its efficacy and suggesting avenues for further study.

19 Sep 2023

Two of four sepsis screening tools inadequate for EMS use, study finds

Two out of the four internationally-recommended screening tools used by emergency medical services are inadequate for recognizing sepsis, according to new research presented at the European Emergency Medicine Congress today (Wednesday).

19 Sep 2023

Tufts Lyme Disease Initiative receives $7M in grants to advance research to next level

Researchers at the Tufts Lyme Disease Initiative recently received grants totaling more than $7 million to build on an already impressive array of discoveries that Tufts' teams have made to combat tick-borne diseases.

19 Sep 2023

High-intensity exercise may reduce colorectal cancer risk in Lynch Syndrome patients

Regular and intense aerobic exercise may reduce the risk of colorectal cancer in patients with Lynch Syndrome (LS) by improving the immune system's ability to detect and remove potentially harmful cells, according to researchers at The University of Texas MD Anderson Cancer Center.

19 Sep 2023

Research demonstrates a double-acting mechanism for fighting triple-negative breast cancer

Zachary Schug, Ph.D., assistant professor in the Molecular and Cellular Oncogenesis Program of the Ellen and Ronald Caplan Cancer Center at The Wistar Institute, has published a new paper in the journal Nature Cancer.

19 Sep 2023

New treatment approach effectively treats the most aggressive forms of prostate cancer

Researchers at the University of Chicago Medicine Comprehensive Cancer Center established "proof-of-concept" for a new treatment approach that was able to effectively treat the most aggressive forms of prostate cancer. The treatment showed complete tumor control and long-lasting survival without side effects in a mouse model of advanced prostate cancer.

19 Sep 2023

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Immune System News and Research

Cellular crosstalk between mother and offspring is more complex than expected

Peptide vaccine targets H3K27M mutation in midline gliomas, shows promise in early trials

Placental disease: A key contributor to unexplained pregnancy loss

Manipulating mitochondrial electron flow enhances immune response, reduces tumor growth

Compound found in hops can combat metabolic syndrome by reducing Oscillibacter population

Study offers new insight into immune cells critical to successful vaccination against SARS-CoV-2

Could a genetic biomarker predict your risk for severe food allergies?

New trial of a preventive HIV vaccine candidate begins in the United States and South Africa

Mount Sinai secures $6.2 million grant to expand the Cohen Center for Recovery From Complex Chronic Illnesses

Scientists develop Australia’s first-of-its-kind next-gen mpox diagnostic tool

New near-infrared activated photo-oxidants kill cancer cells without oxygen

Flagellin immunization protects mice from detrimental effects of dietary emulsifiers

Early treatment with convalescent plasma may reduce risk of long COVID

AI-based tool can assess pathology slides to identify valuable features of clear cell renal cell carcinoma

Transforming postpartum depression treatment with neurosteroids

Two of four sepsis screening tools inadequate for EMS use, study finds

Tufts Lyme Disease Initiative receives $7M in grants to advance research to next level

High-intensity exercise may reduce colorectal cancer risk in Lynch Syndrome patients

Research demonstrates a double-acting mechanism for fighting triple-negative breast cancer

New treatment approach effectively treats the most aggressive forms of prostate cancer

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