Immune System News and Research

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New contributor to aggressive cancers

Mutations in the cell adhesion molecule known as integrin alpha 7 (integrin 7) lead to unchecked tumor cell proliferation and a significantly higher incidence in cancer spread, or metastasis, in several cancer cell lines, report researchers at the University of Pittsburgh School of Medicine in a study published in the Journal of the National Cancer Institute.

8 Jun 2007

Researchers reprogram normal tissue cells into embryonic stem cells

Researchers at the Institute for Stem Cell Biology and Medicine at UCLA were able to take normal tissue cells and reprogram them into cells with the same unlimited properties as embryonic stem cells, the cells that are able to give rise to every cell type found in the body.

8 Jun 2007

miRNAs shown to be a critical force behind the anti-proliferation potential of p53

Cold Spring Harbor Laboratory (CSHL) researchers led by Lin He, Xingyue He, and Professor and Howard Hughes Medical Investigator (HHMI) Greg Hannon have identified a family of micro RNAs (miRNAs) that enable a critical tumor suppressor network, called the p53 pathway, to fight cancer growth.

8 Jun 2007

Researchers turn normal tissue cells into embryonic stem cells

8 Jun 2007

New bacterium discovered, Bartonella rochalimae

A close cousin of the bacterium that debilitated thousands of World War I soldiers has been isolated at UCSF from a patient who had been on an international vacation.

8 Jun 2007

Inflammation again implicated in atherosclerosis

Men whose blood tests positive for the auto-antibody rheumatoid factor have a three times higher risk of heart disease, according to a study published online ahead of print in Heart .

8 Jun 2007

Endocannabinoids appear to play important role in regulating inflammation

Endocannabinoids seem to play an important role in regulating inflammation processes. Scientists from the University of Bonn have discovered this in experiments on mice.

8 Jun 2007

Aging stem cells in mice may hold answers to diseases of the aged

As stem cells in the blood grow older, genetic mutations accumulate that could be at the root of blood diseases that strike people as they age, according to work done in mice by researchers at the Stanford University School of Medicine.

8 Jun 2007

Parents using Ritalin to get children through exams and divorce

Reports in the Chinese media say some parents are prepared to dose their offspring with powerful drugs to help them through exams.

5 Jun 2007

Researchers find stem cells in colorectal tumors

Researchers at the Stanford University School of Medicine have identified the cancer stem cells that propagate tumors in colon and rectal cancer, a discovery that could lead to improved treatment of this deadly cancer.

5 Jun 2007

Study finds lymphoma drug effective over long term

Eight years after being treated with a new drug for non-Hodgkin's lymphoma, 86 percent of patients were still alive and half had not had a relapse of their disease, according to researchers from the University of Michigan Comprehensive Cancer Center.

5 Jun 2007

Protein S-100 linked to melanoma recurrence

Higher levels of a protein called S-100 in patients with melanoma may correlate with a higher risk of having the disease return, say researchers at the University of Pittsburgh Cancer Institute (UPCI), who presented their findings today at the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

5 Jun 2007

Findings from study of immunotherapy vaccine in prostate cancer patients

Data from an ongoing study designed to explore the biologic and clinical activity of cancer immunotherapy sipuleucel-T, or Provenge, in patients with early stage recurrent prostate cancer who have a rising serum prostate specific antigen (PSA) level, but who have not yet developed metastatic disease will be presented by Oregon Health & Science University Cancer Institute researchers.

5 Jun 2007

Chemotherapy may enhance the effectiveness of the vaccines

Chemotherapy temporarily hinders the body's immune response, creating a concern that it may interfere with the promising new cancer vaccines being used against brain tumors.

5 Jun 2007

FDA provides guidance to help increase supply of influenza vaccines

The U.S. Food and Drug Administration (FDA) has issued final recommendations to increase the supply of safe and effective influenza vaccines for both seasonal and pandemic use.

3 Jun 2007

When HIV and liver disease co-exist

Since successful antiretroviral therapies have made HIV a treatable condition, more HIV patients who are also infected with hepatitis B or C are experiencing the progression of their liver disease.

3 Jun 2007

Study tests oral insulin to prevent type 1 diabetes

University of Florida researchers have begun a clinical study of oral insulin to prevent or delay type 1 diabetes in people at risk for the disease.

3 Jun 2007

Exposure to flu vaccine kick-starts fetal immune system in pregnant mothers

Some researchers have hypothesized that the fetus can be exposed to and mount an immune response against allergens to which the mother has been exposed, and this may have an effect on the development of allergic sensitivity (e.g. eczema and asthma) later in an infant's life.

3 Jun 2007

C-reactive protein identified as marker for prostate cancer survival

Oregon Health & Science University Cancer Institute researchers have identified a protein that is a strong indicator of survival for men with advanced prostate cancer.

3 Jun 2007

New strategy for treating rare muscle disease, kidney disorders

Based on clues provided by a study with transgenic mice, a research group at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), has developed a strategy that will be tested as the first treatment for people with hereditary inclusion body myopathy (HIBM), a rare, degenerative muscle disease.

3 Jun 2007