Immune System News and Research

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Peptide vaccine, Interleukin-2 show promise for patients with metastatic melanoma

For patients with advanced melanoma, which is the most lethal type of skin cancer, the results of a large clinical trial show that a vaccine combined with the immune-boosting drug Interleukin-2 can improve response rate and progression-free survival.

4 Jun 2011

UCLA pediatric investigators earn top accolades at TTCF Faculty Presentation Awards

A new therapy for type 1 diabetes? A promising treatment for deadly viruses? Does a common treatment for children with severe infection actually cause more harm than good? These are important questions being investigated by pediatric researchers at Mattel Children's Hospital UCLA.

4 Jun 2011

Scientists demonstrate why B cells exposed to chronic HIV shut down, how they can be reactivated

Scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have demonstrated why certain immune cells chronically exposed to HIV shut down, and how they can be reactivated.

4 Jun 2011

FSU assistant professor unlocks mysteries of KSHV infection

In the early days of the AIDS epidemic, a once-rare form of cancer known as Kaposi's sarcoma emerged as a frequent harbinger of HIV. Its stigma was best illustrated by Tom Hanks, who portrayed a gay man trying to conceal the cancerous skin lesions from his co-workers in the 1993 movie "Philadelphia."

4 Jun 2011

Ipilimumab and bevacizumab drugs effective in treating metatastic melanoma

A duo of drugs, each targeting a prime survival strategy of tumors, can be safely administered and are potentially more effective than either drug alone for advanced, inoperable melanomas, according to a phase 1 clinical trial led by Dana-Farber Cancer Institute investigators.

4 Jun 2011

Cancer vaccine shows improved response rate in patients

A vaccine for one of the most lethal cancers, advanced melanoma, has improved response rate and progression-free survival for patients when combined with the immunotherapy drug Interleukin-2, according to research led by scientists from The University of Texas MD Anderson Cancer Center and Indiana University Health Goshen Center for Cancer Care.

3 Jun 2011

Mimicry allows bacteria to evade host's defense responses

Deadly bacteria may be evolving antibiotic resistance by mimicking human proteins, according to a new study by the Translational Genomics Research Institute (TGen).

3 Jun 2011

Lung-sparing surgery, photodynamic therapy improve survival of mesothelioma patients

Pleural mesothelioma patients who undergo lung-sparing surgery in combination with photodynamic therapy (PDT) show superior overall survival than patient treated using the conventional therapy of extrapleural pneumonectomy (EPP) with PDT, indicates new research from the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania.

3 Jun 2011

APC8015F investigational vaccine improves survival of prostate cancer patients

Metastatic prostate cancer patients who received an investigational vaccine made from their own frozen immune cells lived 10 months longer than those not treated with it, according to data being presented by researchers from the Kimmel Cancer Center at Jefferson at the 2011 American Society of Clinical Oncology annual meeting in Chicago on Saturday, June 4.

3 Jun 2011

New approach for identifying 'self' proteins targeted in autoimmune diseases

Researchers from Harvard Medical School and MIT have developed a new approach for identifying the "self" proteins targeted in autoimmune diseases such as multiple sclerosis, diabetes and rheumatoid arthritis.

3 Jun 2011

Positive interim results from iBio's H1N1 influenza subunit vaccine Phase 1 trial

iBio, Inc. today announced positive interim results from a Phase 1 clinical trial of an iBioLaunch platform-produced subunit vaccine directed against Influenza A/California/04/09 (H1N1).

3 Jun 2011

Scientists identify protein sorting mechanism used by salivary gland

University of Louisville researchers are one step closer to helping millions of people whose salivary glands no longer work because of disease or damage from treatment of diseases.

3 Jun 2011

Green tea consumption increases number of 'regulatory T cells', prevents autoimmune disease

One of the beneficial compounds found in green tea has a powerful ability to increase the number of "regulatory T cells" that play a key role in immune function and suppression of autoimmune disease, according to new research in the Linus Pauling Institute at Oregon State University.

3 Jun 2011

Removal of tonsils and appendix heightens risk of heart attack: Study

According to a new study surgical removal of tonsils and the appendix before the age of 20 is likely to elevate the risk of a premature heart attack. The researchers found that tonsillectomy (removal of tonsils) increased the risk by 44 per cent and removal of the appendix by 33 per cent. The risk increases were even higher when both the tonsils and appendix were removed.

2 Jun 2011

OncoSec Medical to present results of ElectroImmunotherapy clinical trial in melanoma at ASCO 2011

OncoSec Medical Incorporated, which is developing its advanced-stage ElectroOncology therapies to treat solid tumor cancers, announced today that one of its clinical trial advisers will present results from an ElectroImmunotherapy clinical trial for melanoma at the 2011 American Society of Clinical Oncology Annual Meeting to be held June 4-8 at McCormick Place, Chicago, IL.

2 Jun 2011

Positive interim results from Fraunhofer USA CMB's HAC1 influenza vaccine Phase 1 trial

Fraunhofer USA Center for Molecular Biotechnology, a not-for-profit, Delaware-based organization focused on developing a proprietary plant-based protein production platform and its applications in vaccine and therapeutic fields, today announced positive interim results from the first human trial of plant-produced H1N1 influenza vaccine that began on September 13, 2010.

2 Jun 2011

Symphogen's rozrolimupab Phase 2 data to be presented at European Hematology Association meeting

Symphogen announced today that Phase 2 data will be presented from an open-label, multi-center clinical trial evaluating the safety and tolerability of rozrolimupab in adult, RhD positive, non-splenectomized patients with Immune thrombocytopenia (ITP) at the 16th Congress of the European Hematology Association meeting in London, UK on June 10 from 5:45 to 7:00 PM.

2 Jun 2011

Study finds notable prevalence of childhood abuse in migraine patients

A notable prevalence of childhood abuse - physical, sexual, verbal, or emotional - in migraine patients has been observed and documented over the last few years. In fact, it has emerged as a significant enough issue for the American Headache Society to devote an entire plenary session to it at its annual scientific conference in Washington this week.

2 Jun 2011

Lymphocyte count serves as simple and effective prognostic indicator in renal cell carcinoma

Each year, kidney cancer is diagnosed in nearly 60,000 people in the U.S. Many of these patients undergo surgery to remove the affected kidney, but this procedure can be risky for the elderly and those who have other health problems. Unfortunately, the prognosis of kidney cancer patients often cannot be determined until tumor samples are surgically removed and evaluated.

2 Jun 2011

Adaptimmune announces opening of Phase I/II clinical trial in multiple myeloma

Adaptimmune announced that it has opened a Phase I/II, dual site, two-cohort, open-label clinical trial in multiple myeloma at the University of Maryland and the University of Pennsylvania testing its enhanced T cell receptor T cell therapy.

1 Jun 2011

Immune System News and Research

Peptide vaccine, Interleukin-2 show promise for patients with metastatic melanoma

UCLA pediatric investigators earn top accolades at TTCF Faculty Presentation Awards

Scientists demonstrate why B cells exposed to chronic HIV shut down, how they can be reactivated

FSU assistant professor unlocks mysteries of KSHV infection

Ipilimumab and bevacizumab drugs effective in treating metatastic melanoma

Cancer vaccine shows improved response rate in patients

Mimicry allows bacteria to evade host's defense responses

Lung-sparing surgery, photodynamic therapy improve survival of mesothelioma patients

APC8015F investigational vaccine improves survival of prostate cancer patients

New approach for identifying 'self' proteins targeted in autoimmune diseases

Positive interim results from iBio's H1N1 influenza subunit vaccine Phase 1 trial

Scientists identify protein sorting mechanism used by salivary gland

Green tea consumption increases number of 'regulatory T cells', prevents autoimmune disease

Removal of tonsils and appendix heightens risk of heart attack: Study

OncoSec Medical to present results of ElectroImmunotherapy clinical trial in melanoma at ASCO 2011

Positive interim results from Fraunhofer USA CMB's HAC1 influenza vaccine Phase 1 trial

Symphogen's rozrolimupab Phase 2 data to be presented at European Hematology Association meeting

Study finds notable prevalence of childhood abuse in migraine patients

Lymphocyte count serves as simple and effective prognostic indicator in renal cell carcinoma

Adaptimmune announces opening of Phase I/II clinical trial in multiple myeloma

Immunology eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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