Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Reviving reservoirs: new findings shake up HIV treatment understanding

Researchers provide insight into the interaction between T lymphocytes and persisting reservoirs of HIV, with repercussions for harnessing effective, long-lasting responses to HIV eradication.

14 Sep 2023

Comparing HIV PrEP medications: Study explores hypertension risk in adults on TAF vs. TDF

The risk of hypertension and statin initiation in adults starting Human Immunodeficiency Virus Pre-exposure prophylaxis.

13 Sep 2023

Global case series uncovers Mpox resurgence among previously infected or fully vaccinated individuals

Researchers elucidated monkeypox's (mpox) epidemiological and clinical features.

8 Sep 2023

Study uncovers thousands of medication pairings linked to frequent dosage adjustments

Researchers investigated the complexity of polypharmacy and whether frequent dose adjustments were required for co-medications and drug pairs in hospital settings.

7 Sep 2023

One in three men carry HPV: The ignored reservoir in the fight against cancer

One in three men over 15 globally have at least one incidence of genital HPV, underscoring the need to include males in HPV prevention strategies. The prevalence remains high from young adulthood through later life, particularly for high-risk HPV types linked to cancers.

6 Sep 2023

Researchers unearth secrets of zinc transporter protein

A group of researchers has unearthed the secrets behind a tiny but crucial protein that shuttles zinc ions (Zn2+) within our bodies. The discovery offers a deeper understanding of how our cells maintain optimal health.

31 Aug 2023

Study explores lipid and metabolic alterations in HIV/TB co-infected patients

Researchers investigated the differential impact of HIV/tuberculosis co-infection on lipid and metabolic profiles.

23 Aug 2023

Study evaluates differences in humoral immune response against SARS-CoV-2 in infants versus mothers

Researchers comparatively evaluated humoral immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among infants and their mothers.

16 Aug 2023

Does nutritional support benefit adult pulmonary tuberculosis patients?

Researchers evaluated the impact of nutritional support in Indian adults with microbiologically confirmed pulmonary tuberculosis.

14 Aug 2023

Does convalescent serum treatment lower mortality in SARS-CoV-2-infected individuals?

Researchers evaluated the impact of convalescent serum therapy on all-cause mortality among COVID-19 patients.

14 Aug 2023

Inflammatory profiles in vaccinated vs. unvaccinated individuals following SARS-CoV-2 infection

A group of researchers determined the impact of vaccination on inflammation levels in individuals infected with SARS-CoV-2.

10 Aug 2023

Have social determinants of health affected COVID-19 vaccine uptake?

Researchers investigated clinically significant predictors of COVID-19 vaccination uptake among individuals with social and medical susceptibility to SARS-CoV-2 infection.

10 Aug 2023

Genome editing in the spotlight: genetic disorder carriers' views shape the conversation

Study explores perspectives on the applications of somatic genome editing.

8 Aug 2023

Understanding variations in SARS-CoV-2 evolution and clearance by immunodeficiency status

Researchers describe the virological range of persistent SARS-CoV-2 infection in immunosuppressed individuals.

7 Aug 2023

People living with HIV respond well to COVID-19 infection and vaccination

Researchers examine the antibody response to natural infection or COVID-19 vaccination in individuals living with HIV infection.

7 Aug 2023

Study sheds light on mechanisms behind a rare disease found almost exclusively in boys

A University of Ottawa-led research team has published rigorous new research that advances a quest to understand a puzzling – and heartbreaking – ultra-rare disease that's found almost exclusively in boys.

3 Aug 2023

Genome-wide study finds link between CHD1L gene and HIV control

"We searched for human genetic variation that associates with spontaneous control of HIV and identified a novel region in the genome that is only variable in populations of African ancestries," says Professor Jacques Fellay at EPFL's School of Life Sciences.

2 Aug 2023

Child-friendly HIV drug could improve treatment outcomes

Researchers at the University of Colorado Anschutz Medical Campus have helped confirm the dosing, safety and effectiveness of a drug formulation designed for treating children with human immunodeficiency virus (HIV).

2 Aug 2023

New gene editing approach could revolutionize the treatment of blood disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

27 Jul 2023

Study highlights advantages of syphilis self-testing: convenience, privacy, and rapid results

Researchers performed a meta-analysis on the utility of syphilis self-testing (SST).

26 Jul 2023