Immunohistochemistry News and Research

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Immunohistochemistry (IHC) is an imaging technique to visualize antigens in cells. Labeled antibodies bind to target antigens in the cell to image the distribution and localization of specific proteins of interest

Does SARS-CoV-2 infection contribute to adrenal gland dysfunction?

New research suggests that SARS-CoV-2 infection can directly target and cause cellular damage to the adrenal glands.

23 Nov 2021

A measles-vectored COVID-19 vaccine induces strong immunity in animal model

A new study explores the potential of MV-based vaccines targeting the S protein of SARS-CoV-2.

9 Nov 2021

“Catching SARS-CoV-2 in the act” – viral infection of nasal mucosa spares nerve cells

A new study discusses the entry of SARS-CoV-2 into the respiratory and olfactory mucosa of the nasal cavity.

4 Nov 2021

Impact of SARS-CoV-2 infection on human semen quality

A new review article aimed to extract, review and summarize these articles from the mentioned databases to determine the link between SARS-CoV-2 infection and semen quality.

3 Nov 2021

Researchers develop a new test to more easily diagnose medulloblastoma

Researchers at the University of British Columbia and BC Cancer, in partnership with BC Children's Hospital Research Institute, have developed a new test to more easily diagnose medulloblastoma, the most common malignant childhood brain tumor.

1 Nov 2021

High levels of cancer-fighting immune cells could indicate a better chance of survival

Cancerous tumors are made up of many more components than just malignant cells from the tissue of origin. Immune cells can be recruited to the tumor site and form what is known as the tumor microenvironment.

18 Oct 2021

Advancing ethical recombinant antibody research with the customer in mind

In this interview, News-Medical speaks to Dr. Tillmann Ziegert, Managing Director at Biorbyt Ltd, about the balance between enhancing ethical research opportunities and keeping customers at center stage.

From Biorbyt 15 Oct 2021

RUDN study reveals macrophage dynamics in the regenerating liver after resection

RUDN University discovered the features of liver macrophages activation during its regeneration. In future, it can be used to develop new treatment methods for liver cirrhosis. The results are published in the Biomedicine.

15 Oct 2021

R37 MERIT Award supports innovative ovarian cancer research

One of the most impactful advancements during the past decade in treating ovarian cancer is the use of PARP inhibitors (short for poly adenosine diphosphate-ribose polymerase). PARP inhibitors are a type of cancer drug that blocks the PARP enzyme from helping to repair DNA damage in cancer cells.

18 Sep 2021

Digital spatial profiling of individual glomeruli from HIV and COVID-19 patients

Now, a new study posted to the bioRxiv* server by scientists from the University of Washington explores the use of NanoString’s GeoMx digital spatial profiling (DSP) to investigate CG caused by HIV and SARS-Cov-2 infections.

14 Sep 2021

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

In a recent study, authors explore the relationship between age and immune response to COVID-19.

13 Sep 2021

Vesicular stomatitis virus-based COVID vaccines demonstrate potent antiviral efficacy against SARS-CoV-2 variants

Scientists from the National Institutes of Health, USA, have recently demonstrated the immunogenicity and protective efficacy of two vesicular stomatitis virus (VSV)-based coronavirus disease 2019 (COVID-19) vaccines in hamsters.

6 Sep 2021

Attenuated virulence and protective immunity in SARS-CoV-2 with a mutation in the S1/S2 cleavage site

A new study published in mBio investigates the impact of the furin cleavage site on viral growth and pathogenesis.

31 Aug 2021

Study offers hope for an era of safer chemotherapy in breast cancer

Breast cancer is the deadliest and most common type of cancer in women. The treatment options often require administration of anti-cancer drugs in high doses, as the cells develop resistance towards chemotherapy, leading to painful side effects in patients.

23 Aug 2021

Study in dogs may lead to better understanding of how gliomas affect the immune system

A new study reveals that high-grade gliomas, or brain tumors, in dogs contained more immune cells associated with suppressing immune response than low-grade gliomas.

20 Aug 2021

Durable highly protective T cell response to AAV-spike vaccine against COVID-19 pneumonia in mice

New research, available as a preprint on the bioRxiv* server, has focused on the role played by T cell immunity, particularly CD8+ cytotoxic T cells, on preventing lethal infection with SARS-CoV-2 in mice infused with peptide-loaded antigen-presenting dendritic cells (DCs).

19 Aug 2021

Immunohistochemistry News and Research

Further Reading

Does SARS-CoV-2 infection contribute to adrenal gland dysfunction?

A measles-vectored COVID-19 vaccine induces strong immunity in animal model

“Catching SARS-CoV-2 in the act” – viral infection of nasal mucosa spares nerve cells

Impact of SARS-CoV-2 infection on human semen quality

Researchers develop a new test to more easily diagnose medulloblastoma

High levels of cancer-fighting immune cells could indicate a better chance of survival

Advancing ethical recombinant antibody research with the customer in mind

RUDN study reveals macrophage dynamics in the regenerating liver after resection

R37 MERIT Award supports innovative ovarian cancer research

Digital spatial profiling of individual glomeruli from HIV and COVID-19 patients

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

Vesicular stomatitis virus-based COVID vaccines demonstrate potent antiviral efficacy against SARS-CoV-2 variants

Attenuated virulence and protective immunity in SARS-CoV-2 with a mutation in the S1/S2 cleavage site

Study offers hope for an era of safer chemotherapy in breast cancer

Study in dogs may lead to better understanding of how gliomas affect the immune system

Durable highly protective T cell response to AAV-spike vaccine against COVID-19 pneumonia in mice

Role of neutrophil-epithelial interactions in SARS-CoV-2 infection

PD1 gene deletions associated with worse prognoses of cutaneous T-cell lymphomas

Nasal version of AstraZeneca SARS-CoV-2 vaccine prevents infection in animal models

New molecular and morphologic insights into chronic rejection after lung transplantation

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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