Immunosuppression News and Research

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Immunosuppression involves an act that reduces the activation or efficacy of the immune system. Some portions of the immune system itself have immuno-suppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions.

Discovery of mechanism by which Ebola and Marburg viruses cause disease

Researchers in the Greene Infectious Disease Laboratory at Columbia University's Mailman School of Public Health, the Centers for Disease Control and Prevention, and the Caribbean Primate Research Center have discovered a key mechanism by which the Filoviruses, Ebola and Marburg, cause disease.

16 Oct 2006

Renal transplantation in children with posterior uUrethral valves

The first description of posterior urethral valves (PUV) was made more than 80 years ago by Hugh Hampton Young and represents a spectrum of severity, ranging from disease incompatible with postnatal life to minimal symptoms that may not manifest until later in life.

17 Aug 2006

New findings support Rapamycin's role as cancer treatment

Scientists have long known that the blood vessels of tumors differ markedly from normal blood vessels.

14 Aug 2006

Natural mechanism protecting tissue allografts from rejection

A molecule expressed during pregnancy seems to turn down the immune system, making it more tolerant of welcome visitors such as a fetus or maybe a transplanted heart, researchers say.

10 Jul 2006

Summer sun safety - research reveals significant link to melanoma

Fifty years of medical studies show that sun exposure is a primary component in the development of melanoma, the most serious and deadly type of skin cancer, report leading dermatologists in the April 2006 issue of Dermatologic Surgery.

9 May 2006

Outcome of patients with hepatitis B and HIV infections referred for liver transplantation

A new study on HIV patients who also had Hepatitis B virus (HBV) found that better outcomes are possible if they are referred early for transplant and treated with a combination of drugs for HBV. It is essential to monitor the HBV status of these patients, however, in order to control the emergence of drug-resistant HBV infection.

3 May 2006

Single dose of stem cells produce robust behavioral recovery in animal models for stroke, cerebral palsy

A single dose of adult donor stem cells given to animals that have neurological damage similar to that experienced by adults with a stroke or newborns with cerebral palsy can significantly enhance recovery from these types of injuries, researchers say.

11 Apr 2006

Rapamycin (sirolimus) may be effective in treating kidney disease

A widely available drug may be effective in treating kidney disease, report scientists at the University of California, Santa Barbara. They describe the discovery in the online edition of the Proceedings of the National Academies of Science.

21 Mar 2006

Validation of cardiovascular risk scores in a liver transplant population

Two methods of assessing a patient's risk of cardiovascular events - SCORE and PROCAM - proved more valuable for liver transplant recipients than an alternative method, according to a new study.

7 Mar 2006

Researchers transplant insulin-producing neonatal porcine islet cells into monkeys

A team of researchers from the University of Alberta, the Yerkes National Primate Research Center of Emory University and the Emory Transplant Center has successfully transplanted insulin-producing neonatal porcine islet cells into monkeys, a procedure the researchers say represents a promising intermediate solution to the critical supply problem in clinical islet cell transplantation.

27 Feb 2006

Herbal supplements and plastic surgery don't mix well

Natural herbal supplements are supposed to help boost our immune systems, give us more energy and make us generally healthier.

14 Feb 2006

Sirolimus reduces risk of cancer in kidney transplant patients

A new study published in this month's issue of the Journal of the American Society of Nephrology shows that the risk of cancer in kidney transplant recipients was reduced by more than 50% at five years post transplantation in those patients who were treated with sirolimus following withdrawal of cyclosporine at three months.

13 Feb 2006

Cyclosporine suppresses hepatitis C virus and increases the chance of a sustained virological response after liver transplantation

Liver transplant patients with hepatitis C virus (HCV) achieved significantly better long-term viral response when taking the immunosuppressive agent Cyclosporine along with interferon-ribavirin combination therapy. Cyclosporine also showed efficacy against Hepatitis C virus in vitro.

5 Jan 2006

French woman has worlds' first face transplant

The operation apparently lasted several hours where tissues, muscles, arteries and veins were taken from a brain-dead donor and attached to the patient's lower face.

30 Nov 2005

Ischemic brain injury - another promising avenue for stem cell therapy

Adult stem cell therapy quickly and significantly improves recovery of motor function in an animal model for the ischemic brain injury that occurs in about 10 percent of babies with cerebral palsy, researchers report.

4 Oct 2005

People who receive a kidney transplant are nearly four times more likely to develop melanoma

...a rare but deadly form of skin cancer, according to a study led by Christopher Hollenbeak, Ph.D., associate professor, Departments of Surgery and Health Evaluation Sciences, Penn State College of Medicine, Penn State Milton S. Hershey Medical Center.

28 Sep 2005

Transplanted insulin-producing cells survive better when the activation of NKT cells are blocked

Scientists in Japan have found a way to improve on a promising diabetes treatment. In the October 3 issue of The Journal of Experimental Medicine, Masaru Taniguchi and colleagues report that transplanted insulin-producing cells survive better when the activation of a specific type of immune cell is blocked.

27 Sep 2005

People who receive a kidney transplant are nearly four times more likely to develop melanoma

...a rare but deadly form of skin cancer, according to a study in the November 1, 2005 issue of Cancer, a peer-reviewed journal of the American Cancer Society.

26 Sep 2005

Dental problems caused by radiation, chemotherapy should be treated before a child undergoes immunosuppression as part of bone marrow transplantation therapy

Many children who undergo bone marrow transplantation (BMT) as part of cancer treatment already have dental abnormalities that leave them vulnerable to potentially life-threatening bacterial infections, according to investigators at St. Jude Children's Research Hospital. A report on this study appears in the prepublication online edition of Bone Marrow Transplantation.

29 Aug 2005

SPF may not be enough to protect against skin cancer

Immune protection factor (IPF) in sunscreens and its relation to sun protection factor (SPF) is essential in determining skin cancer prevention ability, researchers found.

29 Aug 2005

Immunosuppression News and Research

Further Reading

Discovery of mechanism by which Ebola and Marburg viruses cause disease

Renal transplantation in children with posterior uUrethral valves

New findings support Rapamycin's role as cancer treatment

Natural mechanism protecting tissue allografts from rejection

Summer sun safety - research reveals significant link to melanoma

Outcome of patients with hepatitis B and HIV infections referred for liver transplantation

Single dose of stem cells produce robust behavioral recovery in animal models for stroke, cerebral palsy

Rapamycin (sirolimus) may be effective in treating kidney disease

Validation of cardiovascular risk scores in a liver transplant population

Researchers transplant insulin-producing neonatal porcine islet cells into monkeys

Herbal supplements and plastic surgery don't mix well

Sirolimus reduces risk of cancer in kidney transplant patients

Cyclosporine suppresses hepatitis C virus and increases the chance of a sustained virological response after liver transplantation

French woman has worlds' first face transplant

Ischemic brain injury - another promising avenue for stem cell therapy

People who receive a kidney transplant are nearly four times more likely to develop melanoma

Transplanted insulin-producing cells survive better when the activation of NKT cells are blocked

People who receive a kidney transplant are nearly four times more likely to develop melanoma

Dental problems caused by radiation, chemotherapy should be treated before a child undergoes immunosuppression as part of bone marrow transplantation therapy

SPF may not be enough to protect against skin cancer

E-Cigarettes and Ethanol: A forensic Perspective on Vaping

Understanding Consumer-Consented Data to Optimize Digital Health Programs

The Future is Wearable: Advancing Human Health Through Portable Spectroscopy

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