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Heparanase shows potential as cancer drug

Laboratory experiments have previously shown that cancer cells overproduce an enzyme, heparanase, which splits the body's own polysaccharide heparan sulfate into shorter fragments.

22 Oct 2007

Extract of broccoli sprouts protects from ultraviolet radiation

A team of Johns Hopkins scientists reports in this week's issue of the Proceedings of the National Academy of Sciences that humans can be protected against the damaging effects of ultraviolet (UV) radiation - the most abundant cancer-causing agent in our environment - by topical application of an extract of broccoli sprouts.

22 Oct 2007

Discovery of two genes linked to a disabling form of arthritis called ankylosing spondylitis

An international team of researchers led by a Fred Hutchinson Cancer Research Center geneticist has discovered two genes linked to a disabling form of arthritis called ankylosing spondylitis, a painful and progressive disease in which some or all of the spine's vertebrae fuse together.

22 Oct 2007

Smurfs a major cause of osteoarthritis

A new clinical trial seeks to predict who is most likely to experience osteoarthritis, and to test whether an experimental treatment can prevent it altogether.

19 Oct 2007

West Nile virus' spread through nerve cells linked to serious complication

Scientists believe they have found an explanation for a puzzling and serious complication of West Nile virus infection.

19 Oct 2007

Preventing tuberculosis reactivation

Tuberculosis (TB) is the leading cause of death due to infectious disease in the world today.

19 Oct 2007

Immune cells found to promote formation of new blood vessels - potential for endometriosis treatments

A discovery in mice of immune cells that promote the formation of new blood vessels could lead to new treatments for endometriosis, a painful condition associated with infertility that affects up to 15 percent of women of reproductive age.

19 Oct 2007

FDA expands approved age range for Menactra, bacterial meningitis vaccine

The U.S. Food and Drug Administration has expanded the approved age range for Menactra, a bacterial meningitis vaccine, to include children ages 2 to 10 years.

19 Oct 2007

Abbott creates one molecule with two antibody functions

Abbott has reported that its scientists are the first to discover a proprietary technology that combines the function and specificity of two or more monoclonal antibodies (mAbs) into one molecular entity that demonstrates drug-like properties and manufacturing feasibility.

19 Oct 2007

Study looks at sepsis and purpura in children

While survival rates for sepsis have increased over the past two decades, children under four and those in adolescence remain highly susceptible to the condition.

18 Oct 2007

Honey for wound healing

Surgeons are being advised to consider the supermarket as well as the drugs cupboard when it comes to effective wound healing, according to a research review published in the October issue of IJCP, the International Journal of Clinical Practice.

18 Oct 2007

Lidocaine lollipop helps prepare for upper GI endoscopy

Researchers at the American University of Beirut Medical Center (AUBMC) in Lebanon have found that administering a lidocaine lollipop as a single-agent anesthetic to patients undergoing an upper gastrointestinal (GI) endoscopy procedure eliminated the need for sedation in the majority of patients.

17 Oct 2007

Long-term high-dose ibuprofen slows the rate of decline in lung function in children with cystic fibrosis

The most important clinical problem for people with cystic fibrosis (CF) is inflammation of their lungs.

17 Oct 2007

Farm children have lower risk of asthma

Farm children appear to have a lower risk of asthma than their urban counterparts or even those living in a non-agricultural rural environment, according to a University of Alberta study.

17 Oct 2007

Inflammatory breast cancer

Inflammatory breast cancer is a rare and little-known form of breast cancer that produces no lumps and can not usually be detected with a mammogram. Experts say thousands of women develop it each year, but unfortunately, many of them miss the early symptoms.

16 Oct 2007

Weight loss before bariatric surgery linked to shorter hospital stay

High-risk morbidly obese patients who lose 5 to 10 percent of their excess body weight before undergoing gastric bypass surgery appear to have shorter hospital stays and more rapid postoperative weight loss, according to a report in the October issue of Archives of Surgery, a theme issue on bariatric surgery.

16 Oct 2007

Optical coherence tomography helps track multiple sclerosis

A five-minute eye exam might prove to be an inexpensive and effective way to gauge and track the debilitating neurological disease multiple sclerosis, potentially complementing costly magnetic resonance imaging to detect brain shrinkage - a characteristic of the disease's progression.

16 Oct 2007

Hospital chairman quits over superbug scandal

Following a report that as many as 345 patients may have died from an infection contracted at a British hospital, the chairman of the hospital trust at the centre of the infection scandal has resigned.

16 Oct 2007

New analyses of long-term LIALDA (mesalamine) data presented at ACG

Post-hoc and other analyses of secondary endpoints of a long-term safety and tolerability study of Shire plc's ulcerative colitis (UC) drug LIALDA (mesalamine) provide further data on LIALDA in patients with mild to moderate ulcerative colitis.

16 Oct 2007

Chemists turn carbon monoxide into potential cardiovascular therapy

During Carbon Monoxide Awareness week, EPSRC highlights how researchers are harnessing the gas for beneficial use.Despite its deadly reputation, the gas carbon monoxide (CO) could actually save lives and boost health in future as a result of leading-edge UK research.

16 Oct 2007