Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Generex announces participation in Annual Canadian Diabetes Association Conference

Generex Biotechnology Corporation today announced that it will be attending the 13th Annual Canadian Diabetes Association (CDA)/ Canadian Society of Endocrinology and Metabolism (CSEM)Professional Conference and Annual Meetings in Edmonton, Alberta. The gathering will run from October 20-23, 2010 at the Shaw Conference Centre.

21 Oct 2010

DMC concludes Protege Phase 3 clinical trial for type 1 diabetes lacks efficacy

MacroGenics, Inc. and Eli Lilly and Company today announced that the Protege Data Monitoring Committee (DMC), composed of independent experts in the fields of diabetes and biostatistics, has completed a planned analysis of one-year safety and efficacy data of the Protege Phase 3 clinical trial of teplizumab, an investigational biologic under development for the treatment of individuals with recent-onset type 1 diabetes.

21 Oct 2010

FDA issues complete response letter for BYDUREON NDA

Amylin Pharmaceuticals, Inc., Eli Lilly and Company and Alkermes, Inc. today announced that the U.S. Food and Drug Administration (FDA) has issued a complete response letter regarding the New Drug Application (NDA) for BYDUREON™ (exenatide extended-release for injectable suspension).

21 Oct 2010

Overweight dads may pass on diabetes to their daughters: Study

According to a latest study fathers on a high-fat diet are more likely to produce daughters with a higher diabetes risk. The study was published in the journal Nature and it involved laboratory rats.

20 Oct 2010

Study shows impaired insulin sensitivity may serve as mediator between obesity and cognitive decline

Because of impairments in their insulin sensitivity, obese individuals demonstrate different brain responses than their normal-weight peers while completing a challenging cognitive task, according to new research by psychologists at The University of Texas at Austin.

20 Oct 2010

Research paves way to understand the mechanism of leptin therapy to improve type 1 diabetes

New findings by UT Southwestern Medical Center researchers suggest a novel role for the brain in mediating beneficial actions of the hormone leptin in type 1 diabetes.

20 Oct 2010

Feds ask Connecticut to reconsider rate hike approval, other health law implementation news

The Hartford Courant reports that a high-ranking health official in the Obama administration has asked Connecticut insurance regulators to reconsider allowing Blue Cross Blue Shield in Connecticut to raise health insurance rates by as much as 47 percent.

20 Oct 2010

En Ze Jia Shi Pharmaceuticals receives patent for controlled-release oral gliclazide

Lotus Pharmaceuticals, Inc.a fast-growing, profitable developer, manufacturer and seller of medicine and drugs in the People's Republic of China announced today that its wholly owned subsidiary, En Ze Jia Shi Pharmaceuticals, has been issued a patent by the State Intellectual Property Office of the People's Republic of China for controlled-release oral gliclazide. The patent covers the composition and preparation methods for the drug through 2030.

20 Oct 2010

Study finds adipose dysfunction linked to steatosis, necroinflammation in G1 CHC patients

Researchers at the University of Palermo in Italy provide the evidence that a higher visceral adiposity index score-a new index of adipose dysfunction-has a direct correlation with viral load and is independently associated with both steatosis and necroinflammatory activity in patients with genotype 1 chronic hepatitis C (G1 CHC).

20 Oct 2010

ACG 75th Scientific Meeting to review advances in gastrointestinal research, treatment of digestive diseases

Many of the world's preeminent gastroenterologists will gather for the American College of Gastroenterology's (ACG) 75th Annual Scientific Meeting at the Henry B. Gonzalez Convention Center in San Antonio, Texas starting Monday October 18, 2010, to review the latest scientific advances in gastrointestinal research, treatment of digestive diseases and clinical practice management.

19 Oct 2010

An overview on American College of Gastroenterology's Annual Scientific meeting

The association between obesity and gastrointestinal-related cancers and coronary artery disease; the link between an overweight or obese body mass index and the severity of Crohn's disease; and whether inflammatory bowel disease is an independent risk factor for coronary artery disease, were among the highlights of new research that was presented this week at the American College of Gastroenterology's (ACG) 75th Annual Scientific meeting in San Antonio.

19 Oct 2010

MPI of Biochemistry and GSK collaborate in development of new drugs for type 2 diabetes

The recently signed cooperation agreement between the MPI of Biochemistry and GSK pursues the objective of developing innovative new drugs. The joint research and development work is based on the research findings of Axel Ullrich, Director at the MPI of Biochemistry.

19 Oct 2010

Peer partner program helps diabetic patients to manage their conditions

Phone calls with a peer facing the same self-management challenges helped diabetes patients manage their conditions and improved their blood sugar levels better than those who used traditional nurse care management services alone, according to research from the University of Michigan Health System.

19 Oct 2010

Study investigates effectiveness of potential treatment for Non-alcoholic steatohepatitis

Estimates of the prevalence of liver disease suggest that one‐third of the United States population has non‐alcoholic fatty liver disease (NAFLD). NAFLD is now the most common cause for elevated liver function tests in the United States, a trend related to the obesity epidemic in this country. Non-alcoholic steatohepatitis (NASH), the progressive form of NAFLD, can lead to cirrhosis and all its complications.

19 Oct 2010

Type 2 diabetes and insulin use associated with CRC risk in men, but not women

There is an association between type 2 diabetes mellitus and colorectal cancer (CRC) among men, but not women, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.

19 Oct 2010

Biocon, Pfizer enter global agreement to commercialize Insulin analog products

Biocon, Asia's premier biotechnology company, and Pfizer Inc. (NYSE: PFE), the world's leading biopharmaceutical company, today announced that they have entered into a strategic global agreement for the worldwide commercialization of Biocon's biosimilar versions of Insulin and Insulin analog products: Recombinant Human Insulin, Glargine, Aspart and Lispro.

18 Oct 2010

New rates and benefits for 2011 from APWU Health Plan

APWU Health Plan announces new rates and benefits for 2011. APWU Health Plan continues to offer comprehensive health care to America's Workforce at a competitive premium. The average rate increase for the FEHB Program in 2011 is 7.2 percent. For the tenth straight year, the APWU Health Plan's rate increase was below the FEHB average.

15 Oct 2010

Research team creates first 'lipidome' of human plasma

Human blood is famously fraught with fats; now researchers have a specific idea of just how numerous and diverse these lipids actually are. A national research team, led by scientists at the University of California, San Diego School of Medicine, has created the first "lipidome" of human plasma, identifying and quantifying almost 600 distinct fat species circulating in human blood.

15 Oct 2010

Study reveals copy number variants exclusive to obese children

A new study by pediatric researchers has added to the evidence that genes have a strong influence on childhood obesity.

15 Oct 2010

Research finds fat cells can secrete hormones

Scientists are reporting new evidence that the fat tissue in those spare tires and lower belly pooches - far from being a dormant storage depot for surplus calories - is an active organ that sends chemical signals to other parts of the body, perhaps increasing the risk of heart attacks, cancer, and other diseases. They are reporting discovery of 20 new hormones and other substances not previously known to be secreted into the blood by human fat cells and verification that fat secretes dozens of hormones and other chemical messengers.

14 Oct 2010

Insulin News and Research

Further Reading

Generex announces participation in Annual Canadian Diabetes Association Conference

DMC concludes Protege Phase 3 clinical trial for type 1 diabetes lacks efficacy

FDA issues complete response letter for BYDUREON NDA

Overweight dads may pass on diabetes to their daughters: Study

Study shows impaired insulin sensitivity may serve as mediator between obesity and cognitive decline

Research paves way to understand the mechanism of leptin therapy to improve type 1 diabetes

Feds ask Connecticut to reconsider rate hike approval, other health law implementation news

En Ze Jia Shi Pharmaceuticals receives patent for controlled-release oral gliclazide

Study finds adipose dysfunction linked to steatosis, necroinflammation in G1 CHC patients

ACG 75th Scientific Meeting to review advances in gastrointestinal research, treatment of digestive diseases

An overview on American College of Gastroenterology's Annual Scientific meeting

MPI of Biochemistry and GSK collaborate in development of new drugs for type 2 diabetes

Peer partner program helps diabetic patients to manage their conditions

Study investigates effectiveness of potential treatment for Non-alcoholic steatohepatitis

Type 2 diabetes and insulin use associated with CRC risk in men, but not women

Biocon, Pfizer enter global agreement to commercialize Insulin analog products

New rates and benefits for 2011 from APWU Health Plan

Research team creates first 'lipidome' of human plasma

Study reveals copy number variants exclusive to obese children

Research finds fat cells can secrete hormones

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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