Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Forest Laboratories' Bystolic tablets for treatment of stable CHF failed to receive FDA approval

Forest Laboratories, Inc. announced today that the U.S. Food and Drug Administration did not approve the additional indication for Bystolic® (nebivolol) tablets as a treatment for stable chronic heart failure (CHF) as requested in the company’s Supplemental New Drug Application (sNDA).

23 Feb 2010

Medtronic third-quarter revenues up by 10%

Medtronic, Inc. today reported financial results for the third quarter of fiscal year 2010, which ended January 29, 2010.

23 Feb 2010

Excessive weight gain during pregnancy linked to increased risk of gestational diabetes

Women who gain excessive weight during pregnancy, especially in the first trimester, may increase their risk of developing diabetes later in their pregnancy, according to a study by the Kaiser Permanente Division of Research that appears online in the current issue of Obstetrics and Gynecology.

23 Feb 2010

Phase 3b ODIN study of once-daily PREZISTA in HIV-1 adults presented at CROI 2010

In a new study of treatment-experienced HIV-1-infected adults with no PREZISTA® (darunavir) resistance-associated mutations (RAMs), 72 percent of patients in the PREZISTA/ritonavir (r) (800/100 mg) once-daily arm achieved undetectable viral loads (<50 copies/mL) compared with 71 percent of patients in the PREZISTA/r (600/100 mg) twice-daily arm. The study met its primary objective of non-inferiority. These data from the Phase 3b ODIN study were presented today at CROI 2010, the 17th Conference on Retroviruses and Opportunistic Infections, in San Francisco.

18 Feb 2010

Study shows value-based plans can improve adherence for diabetes medicines

A study by CVS Caremark (NYSE: CVS), published this week in the American Journal of Pharmacy Benefits, finds that insurance benefit designs that reduce the cost of medications for plan participants result in patients being more likely to start and stay on their medication therapy.

17 Feb 2010

When blood sugar levels rise in healthy people, insulin signals cells to increase production: Study

In type 2 diabetes, which is occurring at alarming rates, the hormone insulin does not work effectively to lower blood sugars and patients also do not make enough insulin. These two processes have been widely considered as separate.

16 Feb 2010

p62 and ERK proteins lead to development of obesity and insulin resistance, say scientists

New research by University of Cincinnati scientists implicates a new protein in obesity development and highlights a protein pair's "team effort" in regulating obesity and insulin resistance.

15 Feb 2010

White rye flour bread leads to better insulin and blood sugar levels than wheat bread with rye bran

Wholegrain bread is good and good for you, as most people know. But it is not only the fiber-rich bran, the outer shell of the grain, that is healthful. On the contrary, research at the Lund University Faculty of Engineering shows that bread baked with white rye flour, which is flour made from the inner, white part of the rye kernel, leads to better insulin and blood sugar levels compared with wheat bread with rye bran. White rye flour thus leads to much better values than both regular wheat flour and rye bran. At the same time, much of the bread that is sold in stores today in most countries is in fact baked with wheat flour and bran from various grains.

12 Feb 2010

Center for Adolescent Bariatric Surgery performs 100th LAGB procedure

Few treatments are available to help obese adolescents who are unable to lose weight and are already suffering from obesity-related health problems. Laparoscopic adjustable gastric banding (LAGB), an option for adults in the United States since 2001, is showing promise for teens. The Center for Adolescent Bariatric Surgery, which opened at NewYork-Presbyterian Morgan Stanley Children's Hospital in 2006, recently performed its 100th LAGB procedure.

12 Feb 2010

Nippon Product Acquisition commences tender offer to acquire outstanding shares of Home Diagnostics

Nipro Corporation, through its wholly-owned subsidiary Nippon Product Acquisition Corporation (the “Purchaser”), today commenced a cash tender offer to purchase all outstanding shares of Home Diagnostics, Inc. pursuant to an Agreement and Plan of Merger among Nipro, the Purchaser and Home Diagnostics dated February 2, 2010 (the “Merger Agreement”).

11 Feb 2010

Biodel's VIAject insulin Phase 3 study results to be presented at international diabetes conference in Basel

Biodel, Inc. announced today that its chief executive officer, Dr. Sol Steiner, will present results from the company’s two Phase 3 studies with VIAject® ultra-rapid-acting recombinant human insulin in a platform presentation at the 3rd International Conference on Advanced Technologies and Treatments for Diabetes in Basel, Switzerland, on Friday, February 12, 2010, at 1pm central European time.

11 Feb 2010

MUHC commences clinical trial of Exsulin for type 1 diabetes

A clinical trial of Exsulin, an innovative new treatment that targets the underlying cause of type 1 diabetes, has begun at the McGill University Health Centre (MUHC). Under the direction of Dr. George Tsoukas of the MUHC and the McGill University Faculty of Medicine, the study will assess the effectiveness of Exsulin.

11 Feb 2010

10th Annual Spring Meeting of ESC on Cardiovascular Nursing and Allied Professionals

Geneva, situated at the heart of Europe, provides a fitting setting for the 10th Annual Spring Meeting of the European Society of Cardiology Council (ESC) on Cardiovascular Nursing and Allied Professionals (CCNAP), 12 - 13 March 2010, with its special theme: "Uniting to Improve Cardiovascular Practice".

11 Feb 2010

$TZD drug may increase fracture risk in older women$

TZD drug may increase fracture risk in older women

A Henry Ford Hospital study finds women with type 2 diabetes who take a commonly prescribed class of medications to treat insulin resistance may be at a higher risk for developing bone fractures.

10 Feb 2010

AB SCIEX technology solution implemented for anti-doping enforcement at the 2010 Winter Games

While millions of viewers around the world are watching breathtaking ski jumps, razor-sharp skating moves and other awe-inspiring athletic feats in Vancouver over the next few weeks, the official doping control laboratory of the 2010 Winter Games will be casting an equally intent eye on the athletes who are competing.

10 Feb 2010

sanofi-aventis reports 2009 fourth-quarter and full-year net earnings

Commenting on the Group's 2009 performance, sanofi-aventis Chief Executive Officer Christopher A. Viehbacher said, "2009 was the first year of implementation of our new strategy. Major steps have already been achieved in strengthening our growth platforms and reinforcing our R&D pipeline while delivering a double-digit EPS(1) growth".

10 Feb 2010

Soft drinks increase risk of developing pancreatic cancer

Consuming two or more soft drinks per week increased the risk of developing pancreatic cancer by nearly two-fold compared with individuals who did not consume soft drinks, according to a report in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

10 Feb 2010

New nursing education modules now available from March of Dimes

For nurses seeking up-to-date and cost-effective continuing education on the care of mothers and babies, the March of Dimes is now offering three new publications (modules).

9 Feb 2010

Consuming two or more soft drinks per week may increase risk of developing pancreatic cancer

Consuming two or more soft drinks per week increased the risk of developing pancreatic cancer by nearly twofold compared to individuals who did not consume soft drinks, according to a report in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

8 Feb 2010

Athlete hopes for first U.S. cross-country medal; health issues plagued 2006 Olympic bid

Kris Freeman is back in the hunt for an Olympic medal in Vancouver after being named today to the U.S. ski team following a disappointing finish at the 2006 Games in Torino, Italy.

6 Feb 2010

Insulin News and Research

Further Reading

Forest Laboratories' Bystolic tablets for treatment of stable CHF failed to receive FDA approval

Medtronic third-quarter revenues up by 10%

Excessive weight gain during pregnancy linked to increased risk of gestational diabetes

Phase 3b ODIN study of once-daily PREZISTA in HIV-1 adults presented at CROI 2010

Study shows value-based plans can improve adherence for diabetes medicines

When blood sugar levels rise in healthy people, insulin signals cells to increase production: Study

p62 and ERK proteins lead to development of obesity and insulin resistance, say scientists

White rye flour bread leads to better insulin and blood sugar levels than wheat bread with rye bran

Center for Adolescent Bariatric Surgery performs 100th LAGB procedure

Nippon Product Acquisition commences tender offer to acquire outstanding shares of Home Diagnostics

Biodel's VIAject insulin Phase 3 study results to be presented at international diabetes conference in Basel

MUHC commences clinical trial of Exsulin for type 1 diabetes

10th Annual Spring Meeting of ESC on Cardiovascular Nursing and Allied Professionals

TZD drug may increase fracture risk in older women

AB SCIEX technology solution implemented for anti-doping enforcement at the 2010 Winter Games

sanofi-aventis reports 2009 fourth-quarter and full-year net earnings

Soft drinks increase risk of developing pancreatic cancer

New nursing education modules now available from March of Dimes

Consuming two or more soft drinks per week may increase risk of developing pancreatic cancer

Athlete hopes for first U.S. cross-country medal; health issues plagued 2006 Olympic bid

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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