Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Physicians favor agents that can reduce HbA1c levels by 2% in diabetes patients

Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, finds that over 70 percent of surveyed U.S. physicians indicate there is a high need for diabetes drugs with novel mechanisms of action versus 15 percent who say there is a high need for additional DPP-IV inhibitors.

18 Dec 2009

Proprietary adult stem cell platform, an effective treatment for diabetes, shows study

Australia's regenerative medicine company, Mesoblast Limited, today announced significant preclinical trial results showing that the proprietary adult stem cell platform could be an effective treatment for diabetes.

18 Dec 2009

Pico-Tesla commences enrollment in its Magneceutical therapy study for type 2 diabetes

Pico-Tesla, The Magneceutical™ Therapy Company, announced today that it has enrolled the first seven patients for a randomized, double-blind, placebo-controlled Pilot Study of persons who have type 2 diabetes, the most common form of diabetes. The Pilot Study seeks to determine whether the application of magnetic fields generated by the Company’s patented Resonator™ system can be effective as an adjunctive therapy to oral medications in reducing hemoglobin A1c levels.

18 Dec 2009

JDRF to work with Johnson & Johnson to develop drug targets and pathways for treating diabetes

The Juvenile Diabetes Research Foundation, a leader in setting the agenda for diabetes research worldwide, said today that it will begin working with The Johnson & Johnson Corporate Office of Science and Technology, and its affiliates, to speed the development of drug targets and pathways to promote the survival and function of insulin-producing cells in people who have diabetes.

18 Dec 2009

Four commonly used chemotherapy drugs disrupt birth of new brain cells, shows study

Researchers have developed a novel animal model showing that four commonly used chemotherapy drugs disrupt the birth of new brain cells, and that the condition could be partially reversed with the growth factor IGF-1.

18 Dec 2009

Roche discloses results of two of eight taspoglutide T-emerge phase III studies in diabetes patients

Ipsen, an innovation-driven global specialty pharmaceutical group, today announced that its partner Roche has disclosed headline results of the fourth and fifth of eight T-emerge phase III studies in patients with diabetes for taspoglutide, the first once weekly glucagon-like peptide-1 (GLP-1) analogue based on a human sequence.

17 Dec 2009

Researchers identify genetic markers to help treat chronic kidney disease among diabetics

Researchers using a DNA analysis tool developed by the Translational Genomics Research Institute (TGen) and UCLA have identified genetic markers that could help treat chronic kidney disease among diabetics.

17 Dec 2009

Arizona State University and Mayo Clinic team up to explore metabolic syndrome

Arizona State University and Mayo Clinic in Arizona are joining forces in a partnership to investigate metabolic syndrome - a cluster of high-risk medical factors that include increased blood pressure, elevated insulin levels, excess body fat and abnormal cholesterol levels, which can lead to heart disease, stroke and diabetes.

16 Dec 2009

Pancreas removal, and successful isolation and transplantation of insulin producing cells

A 21-year old Airman severely wounded in Afghanistan is recovering at Walter Reed Army Medical Center after several surgeries and an unprecedented transplant.

16 Dec 2009

Study may lead to more targeted research and treatment for memory disorders

The conversations neurons have as they form and recall memories have been decoded by Medical College of Georgia scientists.

16 Dec 2009

Senate Democrats vote against tax amendment

The Senate will vote today on an amendment which would send the healthcare bill back to the Finance Committee to strip out its numerous tax hikes on families making less than $250,000 per year. The vote sets up a showdown for Senate Democrats as President Barack Obama has made a "firm pledge" not to raise "any form" of taxes on these families.

16 Dec 2009

Nutrition education may help diabetes patients to adopt better dietary habits

Nine weeks of education about the glycemic index in foods is enough to encourage adults with type 2 diabetes to adopt better dietary habits that result in improvements to their health, recent research suggests.

16 Dec 2009

Positive results from study comparing exenatide once weekly to BYETTA

Amylin Pharmaceuticals, Inc., Eli Lilly and Company and Alkermes, Inc. today announced positive results from a head-to-head study comparing exenatide once weekly, an investigational diabetes therapy, to BYETTA® (exenatide) injection taken twice daily, in patients with type 2 diabetes.

15 Dec 2009

Study to determine link between insulin glargine and cancer

Type 2 diabetes and obesity are linked to an increased risk of certain cancers. Recently published studies suggested that insulin glargine (a synthetic insulin preparation marketed under the trade name Lantus), may be associated with a higher risk of certain cancers than other insulins or oral glucose lowering medications. However, these studies were unable to control for important factors such as obesity that may have driven the association.

15 Dec 2009

Intensive medical therapy may benefit patients with asymptomatic plaque buildup

Intensive medical therapy, including aggressive control of blood pressure and cholesterol levels, for patients with asymptomatic plaque buildup in their carotid arteries (which supply blood to the brain) appears to be associated with reduced rates of cardiovascular events and reduced risk of microemboli (microscopic-sized blood clots) in the brain arteries, according to a report posted online today that will appear in the February 2010 print issue of Archives of Neurology, one of the JAMA/Archives journals.

15 Dec 2009

Amgen receives worldwide rights to Array’s small-molecule glucokinase activator program

Array BioPharma Inc. and Amgen Inc.(NASDAQ: AMGN) today announced that they entered into an agreement granting Amgen exclusive worldwide rights to Array’s small-molecule glucokinase activator program, including ARRY-403, currently being tested in a Phase 1 clinical trial in patients with Type 2 diabetes.

14 Dec 2009

Scientists present new research on adipocyte regulation

The ninth Colloque Médecine et Recherche of la Fondation Ipsen devoted to Endocrinology, held in Paris on December 4, 2009, has reviewed the recent progress in understanding the regulation of fat storage in the body and the consequences of the breakdown of this regulation.

14 Dec 2009

International experts prepare check-list for identifying insulin and cancer risk

Epidemiological studies are difficult to do well, pharmacoepidemiological studies are particularly complicated and studies of insulin and cancer risk are even more difficult to do well. "Well" in the sense that any association found can be interpreted in an unambiguous manner.

14 Dec 2009

Diabetic patients exposed to insulin glargine have higher incidence of cancer, shows study

14 Dec 2009

Case Western Reserve University grants option to startup Thermalin Diabetes

Case Western Reserve University has granted an 18-month, exclusive option to startup Thermalin Diabetes Inc. regarding a portfolio of insulin analogs. The company must reach certain milestones in order to exercise its option to obtain an exclusive license on therapies designed to help patients with diabetes.

14 Dec 2009

Insulin News and Research

Further Reading

Physicians favor agents that can reduce HbA1c levels by 2% in diabetes patients

Proprietary adult stem cell platform, an effective treatment for diabetes, shows study

Pico-Tesla commences enrollment in its Magneceutical therapy study for type 2 diabetes

JDRF to work with Johnson & Johnson to develop drug targets and pathways for treating diabetes

Four commonly used chemotherapy drugs disrupt birth of new brain cells, shows study

Roche discloses results of two of eight taspoglutide T-emerge phase III studies in diabetes patients

Researchers identify genetic markers to help treat chronic kidney disease among diabetics

Arizona State University and Mayo Clinic team up to explore metabolic syndrome

Pancreas removal, and successful isolation and transplantation of insulin producing cells

Study may lead to more targeted research and treatment for memory disorders

Senate Democrats vote against tax amendment

Nutrition education may help diabetes patients to adopt better dietary habits

Positive results from study comparing exenatide once weekly to BYETTA

Study to determine link between insulin glargine and cancer

Intensive medical therapy may benefit patients with asymptomatic plaque buildup

Amgen receives worldwide rights to Array’s small-molecule glucokinase activator program

Scientists present new research on adipocyte regulation

International experts prepare check-list for identifying insulin and cancer risk

Diabetic patients exposed to insulin glargine have higher incidence of cancer, shows study

Case Western Reserve University grants option to startup Thermalin Diabetes

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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