Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Ostructive sleep apnea and continuous positive airway pressure

Researchers in Brazil have found that treating patients who suffer from obstructive sleep apnea (OSA) with continuous positive airway pressure (CPAP) dramatically reduces early indications of atherosclerosis in just months, linking OSA directly to the hardening or narrowing of the arteries.

29 Sep 2007

Discovery supports theory of Alzheimer's disease as form of diabetes

Insulin, it turns out, may be as important for the mind as it is for the body.

27 Sep 2007

ACTOS associated with reduced risk of heart attack and stroke in patients with type 2 diabetes

Results presented at the 43rd Annual Meeting of the European Association for the Study of Diabetes demonstrate the ability of ACTOS (pioglitazone HCl) to reduce the risk of ischemic cardiovascular disease in patients with type 2 diabetes.

20 Sep 2007

Metformin could potentially improve pregnancy outcomes in women with insulin resistance

Women who are obese, have type 2 diabetes or a family history of type 2 diabetes could one day have more successful pregnancies because of a study at Washington University School of Medicine in St. Louis.

10 Sep 2007

Insights into the physiological basis of obesity

The past decade has witnessed an explosion of information regarding the role of the central nervous system (CNS) in the development of obesity and the influence of peripheral, hormonal signals that regulate CNS function to regulate food intake and metabolism.

3 Sep 2007

New understanding of endoplasmic reticulum

In obese individuals, fat cells are bloated and inflamed because they receive too many nutrients, including lipids.

29 Aug 2007

Higher maternal sugar levels increases risk of childhood obesity

Treating diabetes during pregnancy can break the link between gestational diabetes and childhood obesity, according to a Kaiser Permanente study featured in the September issue of Diabetes Care.

28 Aug 2007

Study looks at salsalate for type 2 diabetes

The University of Illinois at Chicago is one of 16 sites in the United States taking part in the first large-scale study to test a promising approach to lowering blood glucose levels in adults with type 2 diabetes.

24 Aug 2007

Fat mice gain protection against diabetes

The world's fattest mice can overeat without developing insulin resistance or diabetes thanks to a glut of a key hormone, a dichotomy that helps explain why not all obese people are diabetic, a UT Southwestern Medical Center researcher has found.

24 Aug 2007

Cytokines shown to be a cause of type 2 diabetes

In the first large scale, multiethnic study of its kind, researchers at UCLA have confirmed the role played by three particular molecules known as cytokines as a cause of Type 2 diabetes, and further, have identified these molecules as early biological markers that may be used to more accurately predict future incidences of diabetes among apparently healthy individuals.

16 Aug 2007

Diabetes increases risk of death for patients with acute coronary syndromes

Individuals with diabetes and acute coronary syndromes (ACS) such as a heart attack or unstable angina have an increased risk of death at 30 days and one year after ACS, compared with ACS patients without diabetes, according to a study in the August 15 issue of JAMA .

16 Aug 2007

The role of estrogens and polyphenols in hypertension and diabetes

Menopausal women are at relatively high risk for memory loss, high blood pressure (hypertension) and diabetes.

12 Aug 2007

Insulin Resistance Syndrome could be key to preventing cardiovascular disease, cancer, diabetes and Alzheimer's

New and important evidence shows that Insulin Resistance Syndrome can lead to elevated risk for cardiovascular disease, breathing and sleep disorders, liver disease, Polycystic Ovarian Syndrome, type 2 diabetes, certain cancers, Alzheimer's Disease and more.

3 Aug 2007

Reducing inflammation plays key role in type 1 diabetes therapy

Researchers at Beth Israel Deaconess Medical Center (BIDMC) have found that a triple combination therapy consisting of both tolerance-inducing and anti-inflammatory properties is successful in abolishing adverse autoimmunity against insulin-producing cells in a mouse model of Type 1 diabetes.

1 Aug 2007

Trans fats offer a double whammy

Along with the knowledge that 'trans fats' are particularly bad because they clog up arteries and increase the risk of heart attacks comes new information which makes them even more undesirable.

31 Jul 2007

Takeda responds to FDA recommendation on Actos

Following a joint meeting today of the U.S. Food and Drug Administration (FDA) Endocrinologic and Metabolic Drugs Advisory Committee and the Drug Safety and Risk Management Advisory Committee, Takeda Global Research & Development (TGRD) underscores its position that ACTOS(R) (pioglitazone HCl) offers a proven safety profile regarding the risk of cardiovascular disease.

30 Jul 2007

Merck appoints David Kelley, M.D., to key role in growing Diabetes and Obesity franchise

Merck & Co., Inc. has announced that David E. Kelley, M.D., has been named vice president, franchise integrator for Diabetes & Obesity. Dr. Kelley joins Merck after 20 years on staff at the University of Pittsburgh, where he most recently served as professor of medicine and director of the Obesity & Nutrition Research Center.

24 Jul 2007