Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Striking parallelism between humans and horses when it comes to obesity

Horses are inheritably couch potatoes. An overeating, slothful horse leads to an obese horse. Unlike humans, however, horse owners often don't see the dangers of an obese horse.

25 Apr 2007

HIV linked to increased risk of heart attack

Researchers from Massachusetts General Hospital (MGH) have found that infection with HIV, the virus that causes AIDS, is also associated with increased risk of myocardial infarction or heart attack.

25 Apr 2007

Impaired intestinal metabolic function plays a critical role in the development of cardiovascular disease

Nutritional scientists at the University of Alberta are the first to establish a connection between high insulin levels and dysfunction of intestinal lipid metabolism in an animal model.

25 Apr 2007

Steam, boil, stew for food preparation

How your food is cooked may be as important to your health as the food itself. Researchers now know more about a new class of toxins that might soon become as important a risk factor for heart disease and metabolic disorders as trans fats.

25 Apr 2007

Extended bed rest leads to substantial muscle deterioration in older adults

Extended bed rest – often necessary during hospitalization – leads to a substantial amount of muscle deterioration in older adults, researchers at the University of Arkansas for Medical Sciences (UAMS) report in the April 25 issue of the Journal of the American Medical Association .

25 Apr 2007

Twin studies identify genes that influence human health in unexpected ways

Daniel O'Connor, M.D., Professor of Medicine and Pharmacology at the University of California, San Diego (UCSD) School of Medicine has studied about 265 twin pairs over the past few years, which has led him to some surprising discoveries.

18 Apr 2007

Insulin receptors play a critical role in promoting islet growth

A new Joslin-led study has identified the insulin receptor as an important protein that promotes islet cell growth in mice whose bodies are unable to use insulin properly, or are insulin resistant, a precursor to type 2 diabetes.

4 Apr 2007

Researchers spot molecular player in insulin resistance and type 2 diabetes

Scientists at Weill Cornell Medical College have identified a protein called Rab10 as an important partner in the insulin-mediated uptake of glucose by cells, opening the way to potential new drug targets for the prevention and treatment of type 2 diabetes.

3 Apr 2007

Long-term low to moderate doses of aspirin beneficial for women

Women who take low to moderate doses of aspirin have a reduced risk of death from any cause, and especially heart disease related deaths, according to a report in the March 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

2 Apr 2007

Exposure to phthalates linked to abdominal obesity and insulin resistance in adult males

Exposure to phthalates, a common chemical found in everything from plastics to soaps, already has been connected to reproductive problems and now, for the first time, is linked to abdominal obesity and insulin resistance in adult males, according to a study by the University of Rochester Medical Center.

14 Mar 2007

Understanding link between polycystic ovary syndrome and insulin resistance

It is known that women with PCOS have a 3-fold increase in their risk of developing type-2 diabetes, where the body does not produce enough insulin or cannot use insulin properly. Insulin resistance is an important factor in the condition, which is the most common female hormone disorder. PCOS affects between 5 and 10 per cent of women and is a major cause of infertility.

12 Mar 2007

High blood glucose levels may signal an increased risk for cancer in women

The March journal also includes a study that found a link between high levels of persistent organic pollutants (POPs) in a person's bloodstream and insulin resistance, a precursor for type 2 diabetes.

27 Feb 2007

Twin study on the increased cardiometabolic risk in obesity

A unique monozygotic twin study by researchers from the Finnish Twin Cohort, Helsinki University Central Hospital, and VTT Technical Research Centre of Finland found that obesity, already in its early stages and independent of genetic influences, is associated with deleterious alterations in the lipid metabolism known to facilitate atherogenesis, inflammation and insulin resistance.

15 Feb 2007

International consortium to get to heart of coronary artery disease

An international consortium has been launched to tackle coronary artery disease using the latest scientific tools. Funded by the European Commission, the initiative will build on recent advances in genomic science and the understanding of our genes to develop effective strategies for preventing and treating the disease.

7 Feb 2007

Power-boosting signal in muscle declines with age

As people age, they may have to exercise even harder to get the benefits afforded to younger folk. That's the suggestion of a report in the February issue of the journal Cell Metabolism, showing that a signal that gives muscles a kind of metabolic boost in response to exercise is blunted in older animals.

6 Feb 2007

Weight loss supplement - conjugated linoleic acid - shows nasty side effects

A supplement some people turn to in hopes of losing a few pounds may have some previously unknown, unsavory side effects, suggest two new studies.

30 Jan 2007

Healthy 4 year-olds who eat lots of fat weigh less

Four-year-olds eat too few vegetables and too much sugar. They also bolt down lots of junk food, but children who eat more fat than others nevertheless weigh less. This is shown in a new dissertation from the Sahlgrenska Academy at Goteborg University in Sweden.

28 Jan 2007

Melanin concentrating hormone found to be involved with insulin production

A new Joslin Diabetes Center-led study has shown conclusively that a neuropeptide, melanin concentrating hormone (MCH), found in the brain and known for its role in increasing appetite in people, plays a role in the growth of insulin-producing beta cells and the secretion of insulin.

28 Jan 2007

High uric acid levels indicate risk for cognitive problems in old age

Researchers at the Johns Hopkins and Yale university medical schools have found that a simple blood test to measure uric acid, a measure of kidney function, might reveal a risk factor for cognitive problems in old age.

2 Jan 2007

Compound in red wine counters effects of a high-calorie diet

The results of an international study suggests that a compound found in red wine gave mice longer and healthier lives and also countered some of the effects of a high-calorie diet.

1 Nov 2006