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Battle against RSV: Computational design paves way for new polyvalent vaccine

Research focuses on the design of a multi-epitope polyvalent vaccine against Human Respiratory Syncytial Virus (RSV), a leading cause of lower respiratory tract infections. The study utilizes computational methods and immunoinformatics tools to predict potential vaccine candidates and their interactions with Toll-like receptors (TLRs).

19 Jun 2023

Study provides a promising strategy for the treatment of neuroblastoma

Announcing a new publication for Acta Materia Medica journal. Neuroblastoma (NB) is a common solid tumor in children and infants, the formation and regression of which is closely linked to the tumor-host immune relationship.

19 Jun 2023

Herbal extracts for mental health: Are they safe for pregnant women?

Researchers evaluate the T-cell modulating effects of St. John’s wort, valerian, hops, lavender, and California poppy.

18 Jun 2023

Trained immunity: its role in COVID-19 and potential in preparing for future infectious outbreaks

Researchers reported on the contribution of trained immune responses to protection against SARS-CoV-2 infections and future pandemics.

16 Jun 2023

Substance P neuropeptides' role in post-COVID-19 conditions suggested in recent study

Scientists review available evidence on the association between post-COVID-19 conditions and tachykinins.

15 Jun 2023

Molecular insights into long COVID: serum proteome reveals dominant signaling pathways

Researchers examined the serum proteome of unvaccinated adults who had PASC.

15 Jun 2023

Latent tuberculosis infection results for the United States from the 2019–2020 National Health and Nutrition Examination Survey

A recent study published in Emerging Infectious Diseases evaluated latent tuberculosis (TB) infections (LTBIs) in the United States (US) during 2019-20.

15 Jun 2023

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Researchers evaluated the therapeutic efficacy of Navoximod.

13 Jun 2023

Study raises new hopes for blood cancer patients with an incomplete response to CAR T cell therapy

The aim of immunotherapy strategies is to use cells in the patient's own immune system to destroy tumor cells. CAR T cell therapy is an immunotherapy that is effective in treating blood cancer.

12 Jun 2023

Investigating the alveolar type II reparative response in COVID-19 pneumonia

Researchers investigated the alveolar type II reparative response in COVID-19 pneumonia.

9 Jun 2023

Shaping the human metabolome: the impact of a ketogenic diet

Researchers explored how the human metabolic fingerprint changes with a ketogenic diet (KD).

6 Jun 2023

Unraveling the complexity of 'Long-COVID' and its impact on breathing

More than a third of COVID-19 patients experience long-lasting symptoms, known as post-COVID-19 condition or long COVID, with breathlessness being a commonly reported symptom. Pulmonary complications, such as fibrosis and thromboembolic disease, require careful assessment, and non-pharmacological interventions like pulmonary rehabilitation can help manage breathlessness.

5 Jun 2023

Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown

Blood-brain barrier breakdown in multiple sclerosis leads to immune cell infiltration into the central nervous system. Antigen presentation at the barrier promotes CD8+ T cell entry, triggering focal breakdown and hindering their invasion.

4 Jun 2023

The immunopathology of post-acute sequelae of SARS-CoV-2 infection: highlighting the knowledge gaps

The immunopathology of post-acute sequelae of SARS-CoV-2 infection (PASC).

31 May 2023

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Researchers develop a lipid nanoparticle-formulated mRNA-based antigen encoding three SARS-CoV-2 peptides derived from non-structural proteins.

25 May 2023

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

Abdominal obesity increases the risk of severe COVID-19 and mortality due to heightened inflammatory responses, according to a study on Japanese patients and a murine COVID-19 model. Blocking inflammatory cytokines and preventing obesity may improve survival rates.

24 May 2023

Long-term exposure to air pollution associated with higher risk of developing severe COVID-19

A long history of exposure to air pollution is associated with a higher risk of developing severe disease, admission to hospital or an intensive care unit (ICU) and death by COVID‑19 according to a study led by the Barcelona Institute for Global Health (ISGlobal), a research centre supported by the "la Caixa" Foundation.

24 May 2023

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

Researchers analyzed data from three SARS-CoV-2 outbreaks among nursing homes in Belgium.

24 May 2023

Gut bacteria toxins: A hidden trigger for Parkinson's disease?

Gut dysfunction and the presence of lipopolysaccharide (LPS) endotoxins contribute to the pathogenesis of Parkinson's disease (PD), leading to neuroinflammation and neurodegeneration. Modulating the gut microbiome and reducing LPS levels may hold potential as treatment strategies for PD.

24 May 2023

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Research uncovers the association between multiple sclerosis (MS) and antibody reactivity to specific amino acids in CRYAB, along with the increased risk when combined with high EBNA1 responses. The study provides evidence of antibody and T cell cross-reactivity between EBNA1 and CRYAB, highlighting the role of EBV adaptive immune responses in MS development.

21 May 2023

Interferon News and Research

Battle against RSV: Computational design paves way for new polyvalent vaccine

Study provides a promising strategy for the treatment of neuroblastoma

Herbal extracts for mental health: Are they safe for pregnant women?

Trained immunity: its role in COVID-19 and potential in preparing for future infectious outbreaks

Substance P neuropeptides' role in post-COVID-19 conditions suggested in recent study

Molecular insights into long COVID: serum proteome reveals dominant signaling pathways

Latent tuberculosis infection results for the United States from the 2019–2020 National Health and Nutrition Examination Survey

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Study raises new hopes for blood cancer patients with an incomplete response to CAR T cell therapy

Investigating the alveolar type II reparative response in COVID-19 pneumonia

Shaping the human metabolome: the impact of a ketogenic diet

Unraveling the complexity of 'Long-COVID' and its impact on breathing

Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown

The immunopathology of post-acute sequelae of SARS-CoV-2 infection: highlighting the knowledge gaps

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

Long-term exposure to air pollution associated with higher risk of developing severe COVID-19

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

Gut bacteria toxins: A hidden trigger for Parkinson's disease?

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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