Interleukin News and Research

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ARAMIS trial finds no benefit of anakinra in acute myocarditis

The largest randomized controlled trial of patients with acute myocarditis has found that anakinra is safe but does not reduce complications. The late breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

Non-alcoholic steatohepatitis progression blocked by ginger essential oil

Researchers explore the potential utility of ginger essential oil in preventing NASH.

29 Aug 2023

Can the fermentation of foods enhance their antioxidant properties?

In a recent editorial published in Fermentation, researchers highlighted the use of fermentation as a means to increase the antioxidant potential of foods.

29 Aug 2023

Study unveils previously unknown urinary biomarkers, revolutionizing early detection and treatment of viral infections like COVID-19

This recent study identifies new urinary biomarkers for detecting acute COVID-19 using spectroscopic analysis. The findings reveal that these biomarkers could offer valuable tools for early diagnosis, understanding the severity of the disease, and possibly contribute to endogenous immunological defense mechanisms against SARS-CoV-2.

29 Aug 2023

The potential of gut-microbiota-targeted reprogramming interventions designed to prevent the onset and progression of cardiovascular diseases

Researchers discuss the potential of probiotic- and prebiotic-based interventions for managing cardiovascular diseases.

28 Aug 2023

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Researchers described the preclinical profile of JT002, a novel and orally bioavailable small molecule inhibitor of the NLRP3 inflammasome.

24 Aug 2023

Differences in immune responses to IL-6 inhibition therapy between male and female COVID-19 patients

Researchers investigated whether anti‑interleukin 6 monoclonal antibodies were related to heterogenous treatment effects between male and female COVID-19 patients.

24 Aug 2023

Texas Heart Institute receives $1.14 million grant to develop first-in-class drug to treat cardiovascular disease

The National Heart, Lung, and Blood Institute (NHLBI) recently awarded The Texas Heart Institute (THI) a two-year, $1.14 million grant to develop a novel, first-in-class drug to treat cardiovascular disease (CVD) as a significant improvement to current treatment regimens -; specifically for adverse events arising from atherosclerosis.

22 Aug 2023

New microneedles could monitor melanoma therapy response

Patients with melanoma, the most concerning form of skin cancer in which pigment-producing cells start to grow out of control, can benefit from existing immunotherapies, but by far not all of them do.

21 Aug 2023

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Researchers describe molecular signalling regulated by mTOR among memory and exhausted cytotoxic CD8+ T lymphocytes.

18 Aug 2023

New insights into the role of liver progenitor cells in liver cancer initiation

Primary liver cancers ranked as the sixth most commonly diagnosed cancers and the third leading cause of cancer-related death in 2020. Among all primary liver cancers, HCC is the most common cancer, accounting for more than 80% of cases with a 5-year survival rate of less than 10% in Western countries.

17 Aug 2023

Interactomics-based analysis suggests that rhinitis and rhinitis with asthma are mechanistically different diseases

Researchers used human transcriptomic data to differentiate the molecular mechanisms associated with two phenotypes of allergic rhinitis: rhinitis and rhinitis with asthma.

17 Aug 2023

Study finds inverse correlation between dietary magnesium intake and peripheral arterial disease

Researchers conducted a cross-sectional study to investigate the association between dietary magnesium intake and peripheral arterial disease (PAD).

16 Aug 2023

The gut microbiome of critically ill individuals and its modification by immunonutrition and probiotics

Gut dysbiosis among critically ill individuals

16 Aug 2023

Genetic determinants of retinol circulation and their impact on health

The genetic architecture of circulating retinol.

15 Aug 2023

Novel antibody could be safer and more effective than existing treatments for autoimmune diseases

Researchers have shown that a novel antibody generated to target an 'essential amino acid sequence' of both interleukin-17A and F has greater activity and potentially fewer side effects than existing biological therapies for conditions such as as rheumatoid arthritis (RA), psoriasis, and inflammatory bowel disease (IBD).

14 Aug 2023

Interleukin News and Research

ARAMIS trial finds no benefit of anakinra in acute myocarditis

Non-alcoholic steatohepatitis progression blocked by ginger essential oil

Can the fermentation of foods enhance their antioxidant properties?

Study unveils previously unknown urinary biomarkers, revolutionizing early detection and treatment of viral infections like COVID-19

The potential of gut-microbiota-targeted reprogramming interventions designed to prevent the onset and progression of cardiovascular diseases

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Differences in immune responses to IL-6 inhibition therapy between male and female COVID-19 patients

Texas Heart Institute receives $1.14 million grant to develop first-in-class drug to treat cardiovascular disease

New microneedles could monitor melanoma therapy response

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

New insights into the role of liver progenitor cells in liver cancer initiation

Interactomics-based analysis suggests that rhinitis and rhinitis with asthma are mechanistically different diseases

Study finds inverse correlation between dietary magnesium intake and peripheral arterial disease

The gut microbiome of critically ill individuals and its modification by immunonutrition and probiotics

Genetic determinants of retinol circulation and their impact on health

Novel antibody could be safer and more effective than existing treatments for autoimmune diseases

Researchers design one-step procedure for improving effective of adoptive cell immunotherapy against solid tumors

Unveiling hidden threats: clustering loops in CAR-T cells impact cancer therapy

Ovarian cancer patients enrolled in first-in-human trial of CAR T cell therapy

How does sun exposure affect skin microbiota composition and diversity?

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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