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Study provides insights into how immune cells kill bacteria with acid

The first line of immune defense against invading pathogens like bacteria are macrophages, immune cells that engulf every foreign object that crosses their way. After enclosing it in intracellular membrane vesicles, a process called phagocytosis, macrophages kill their prey with acid.

17 May 2018

Lowering blood cholesterol levels could enhance success of T-cell cancer immunotherapy

Cleveland Clinic researchers have demonstrated for the first time that lowering blood cholesterol levels could enhance the success of a specific type of T-cell immunotherapy in fighting cancer.

16 May 2018

New study could have important implications for cellular aging

Researchers have found a way to stimulate autophagy, a process used by cells to convert misfolded proteins and redundant organelles into components that the cell can re-use.

16 May 2018

Researchers demonstrate new strategy for stimulating autophagy

Brown University researchers studying the biology of aging have demonstrated a new strategy for stimulating autophagy, the process by which cells rebuild themselves by recycling their own worn-out parts.

16 May 2018

System designed to enable the control of animal cells using light

Scientists have developed a system of design principles for controlling cells, tissues or entire limbs using silicon-based photostimulation.

2 May 2018

Innovative research could lead to new ways to treat, prevent cancer

Research into cancer can provide new insight into how this disease works and how it can be stopped. The Experimental Biology 2018 meeting will showcase innovative research that could lead to new ways to treat and prevent cancer.

23 Apr 2018

New microscopy techniques allow quasi-biochemical studies on living T cells

A joint study by the TU Wien and the Vienna School of Medicine has now led to a surprising result. While most opinion leaders in the field reasoned that T cell receptors must interact with one another for effective immune-signaling, the Viennese study shows: T cell receptors act alone. The study has now been published in the journal Nature Immunology.

19 Apr 2018

Antimicrobial therapy can prevent occurrence of pneumococcal septicemia

Antimicrobial therapy targeting specific cells in the immune system could prevent sepsis and life-threatening disease in people suffering from pneumonia, new research led by the University of Leicester has shown.

17 Apr 2018

Biologists discover surprising, additional function for soluble form of SNARE protein

In 2013, the Nobel Prize in Physiology or Medicine was awarded to three scientists for their contributions to uncovering the mechanisms governing vesicle transport in cells. Their explanations provided both a conceptual and a mechanistic understanding of basic processes at the most fundamental level.

13 Apr 2018

Japanese researchers develop new compound to enhance recovery of stroke patients

A team of Japanese researchers have developed a new compound that enhanced motor function recovery after brain damage in animal tests, according to a study published in the journal Science.

10 Apr 2018

Resistance training enhances cellular recycling in muscle cells

A new study has shown that resistance training among previously untrained men increases autophagosome content, but that this effect may be blunted by aging.

9 Apr 2018

Vascular stabilization biomarker helps optimize timing of anticancer therapies

Angiogenesis, the formation of new blood vessels, is essential for tumor growth. A new study reported in The American Journal of Pathology describes a vascular stabilization biomarker that can visualize blood vessel activity, thus optimizing the timing of anticancer therapies including anti-angiogenics.

9 Apr 2018

Study provides insights into how male germ cells avoid genome instability

A group of researchers at Osaka University reported the function of GTSF1 in male germ cells. The study, which can be read in EMBO Reports, shows that GTSF1 is an essential factor for secondary piRNA biogenesis by regulating piRNA-mediated cleavage of target RNA.

28 Mar 2018

Cell-penetrating 'nanodrills' could be new platform for intracellular drug delivery

Researchers at Oregon State University and Oregon Health & Science University have created new nanomaterials able to cross cell membranes, establishing a novel platform for the intracellular delivery of molecular drugs and other cargo.

27 Mar 2018

Study uncovers potential therapeutic target against large family of parasites

Apicomplexa form one of the largest and most diverse groups of obligate intracellular parasites, capable of infecting almost every kind of animal.

21 Mar 2018

Neuroscientists identify role of primary visual cortex in integrating head and visual movement signals

Neuroscientists at the Sainsbury Wellcome Centre have identified a circuit in the primary visual cortex (V1) of the brain that integrates head- and visual-motion signals.

15 Mar 2018

New blood test promises to eliminate guesswork in heart attack diagnosis

A new blood test developed by a University of Alberta physician promises to eliminate the guesswork clinicians face with an apparent heart attack.

15 Mar 2018

Study sheds new light on viral replication

Viruses are intracellular parasites that cause disease by infecting the cells in the body and, in a study published today in Nature Microbiology, researchers at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine showed how a common virus hijacks a host cell's protein to help assemble new viruses before they are released.

13 Mar 2018

Scientists link protein to seizure suppression

According to a new study, seizures can be suppressed in the brain by a protein called T-cell intracellular antigen-1 (TIA-1).

8 Mar 2018

Researchers determine cause of difficult-to-control mitochondrial diseases

A Japanese research group has discovered that taurine is conjugated with mitochondrial transfer RNAs (tRNAs), small RNAs that decode genetic information, and that taurine deficiency in tRNA dramatically reduces both mitochondrial protein translation and impairs mitochondrial membrane integrity.

7 Mar 2018