Intracellular News and Research

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Discovery of sugar 'warehouse' provides new metabolic target to regulate immune activity

A surprising discovery that immune cells possess an internal warehouse of glycogen used to activate immune responses could help to increase immune activity in vaccines or suppress immune reactions in autoimmune disease or hyper-inflammatory conditions.

6 Sep 2017

Research provides novel insights into bacterial toxins

A toxin produced by a bacterium that causes urinary tract infections is related to, yet different in key ways from, the toxin that causes whooping cough, according to new research.

5 Sep 2017

Scientists show how receptors for drugs act inside cells

G protein-coupled receptors are the key target of a large number of drugs. Würzburg scientists have now been able to show more precisely how these receptors act in the cell interior.

5 Sep 2017

Research reveals underlying reason for intense pain in patients with shingles

Chickenpox is a typical childhood illness. In most cases, it is benign, and the symptoms disappear within ten days. However, its causative agent, Varicella zoster virus (VZV), remains in the organism forever. In some cases, the virus can be reactivated years later, causing a different disease known as herpes zoster, or shingles.

24 Aug 2017

Neuronal firing patterns influence proliferation, differentiation of oligodendrocyte precursors

Through their pattern of firing, neurons influence the behavior of the cells that upon maturation will provide insulation of neuronal axons, according to a new study publishing 22 August in the open access journal PLOS Biology by Balint Nagy, Maria Kukley and colleagues at the University of Tübingen, Germany.

23 Aug 2017

Scientists show how immune system can be modulated by manipulation of sugar metabolism

In its attempt to fight a serious bacterial infection, caused by listeria, for example, the immune system can become so over-activated that the resulting inflammatory response and its consequences can quickly lead to death.

21 Aug 2017

Study elucidates how aerobic exercise protects the sick heart

Regular exercise is considered an important form of treatment for heart failure, a condition in which the heart is unable to pump enough blood to meet the body's needs.

18 Aug 2017

Research shows how glutamine plays role in regulating cellular differentiation programs

The 200 different types of cells in the body all start with the same DNA genome. To differentiate into families of bone cells, muscle cells, blood cells, neurons and the rest, differing gene programs have to be turned on or off.

17 Aug 2017

Counteracting premature aging

Aging is the continuing process of such stress exposures, and with advancing age (normal aging), we must carry lots of senescent cells within our bodies. Senescent cells also often provide some ‘bad influences’ to surrounding healthy cells; such as chronic inflammation and tumorigenesis

14 Aug 2017

Botulinum neurotoxin type X holds potential to open up new field of toxin therapeutics

Botulinum toxins are currently used on more than 80 medical conditions including Muscle spasms, Overactive bladder, Chronic migraine, Cervical dystonia, Sweating and Cerebral Palsy (CP).

3 Aug 2017

Boise State professors win $37,000 grant from NASA to study impact of bone loss in space

Our slim body of knowledge of the universe is vastly overshadowed by what we do not know – whether there is sentient life on other planets, whether there are other planets that can sustain human life, even how long-term space travel physically affects human beings.

31 Jul 2017

Researchers identify new way to increase immune response against cancer and infections

An international research team led by Université de Montréal medical professor Christopher Rudd, director of research in immunology and cell therapy at Maisonneuve-Rosemont Hospital Research Centre, has identified a key new mechanism that regulates the ability of T-cells of the immune system to react against foreign antigens and cancer.

19 Jul 2017

New partnership to advance novel airway-delivered gene therapy for treating pulmonary hypertension

Mount Sinai has partnered with Theragene Pharmaceuticals, Inc. to advance a novel airway-delivered gene therapy for treating pulmonary hypertension (PH), a form of high blood pressure in blood vessels in the lungs that is linked to heart failure.

13 Jul 2017

First vaccine protecting against gonorrhea provides opportunity for vaccine development

A meningococcal group B vaccine has been found to offer protection against gonorrhea, report researchers. This is the first time a vaccine has protected against the STD and it could open up a new pathway for vaccine development.

11 Jul 2017

New Cornell discovery could lead to effective treatment for tuberculosis

A recent discovery by Cornell University researchers could lead to a new, effective treatment for persistent tuberculosis infections.

7 Jul 2017

UTA awards new grants for research projects that focus on cancer, drug testing, and health of youth

The University of Texas at Arlington has awarded three new seed grants for interdisciplinary research projects that propose new ways to treat skin cancer, provide a new technique for more rapid and cost-effective evaluation of chemotherapy drugs, and to develop innovative programs to reduce the mental health risks of homeless youth.

30 Jun 2017

Intracellular News and Research

Discovery of sugar 'warehouse' provides new metabolic target to regulate immune activity

Research provides novel insights into bacterial toxins

Scientists show how receptors for drugs act inside cells

Research reveals underlying reason for intense pain in patients with shingles

Neuronal firing patterns influence proliferation, differentiation of oligodendrocyte precursors

Scientists show how immune system can be modulated by manipulation of sugar metabolism

Study elucidates how aerobic exercise protects the sick heart

Research shows how glutamine plays role in regulating cellular differentiation programs

Counteracting premature aging

Botulinum neurotoxin type X holds potential to open up new field of toxin therapeutics

Boise State professors win $37,000 grant from NASA to study impact of bone loss in space

Researchers identify new way to increase immune response against cancer and infections

New partnership to advance novel airway-delivered gene therapy for treating pulmonary hypertension

First vaccine protecting against gonorrhea provides opportunity for vaccine development

New Cornell discovery could lead to effective treatment for tuberculosis

UTA awards new grants for research projects that focus on cancer, drug testing, and health of youth

Scientists use supercomputers to test new techniques for early cancer detection

Temple researchers identify protective effects of extra-virgin olive oil against Alzheimer's disease

Chronic pain may occur when receptors migrate from nerve cell's surface to inner chambers

TUM scientists develop new pH sensor that provides insights into tumor metabolism

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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