Intracellular News and Research

RSS

Cempra demonstrates solithromycin's potential against urogenital infections at ECCMID

Cempra, Inc., a clinical-stage pharmaceutical company focused on developing differentiated antibiotics to meet critical medical needs in the treatment of bacterial infections, today announced that it will present data at the European Congress of Clinical Microbiology and Infectious Diseases in Berlin, demonstrating solithromycin's potential to treat urogenital infections and combat challenging pathogens such as enterococci and Legionella pneumophila.

29 Apr 2013

GI nematode infections combat obesity and improve related metabolic disorders

Researchers at the University of Maryland School of Medicine, Baltimore, have shown in a mouse model that infection with nematodes (also known as roundworms) can not only combat obesity but ameliorate related metabolic disorders.

26 Apr 2013

UB researchers develop aniontransporters to trigger cancer cell apoptosis

The journal Accounts of Chemical Research, which has a profound impact on Chemistry and other related sciences, publishes on its current issue the article "Anion Transporters and Biological Systems", signed by Professor Ricardo Pérez Tomás, from the Department of Pathology and Experimental Therapy of the Faculty of Medicine at the University of Barcelona, Roberto Quesada, from the Department of Chemistry of the Sciences Faculty at the University of Burgos, and Philip A. Gale, from the University of Southampton, in the United Kingdom.

22 Apr 2013

ARMGO Pharma gets $1 million to support ARM210 preclinical work for DMD treatment

ARMGO Pharma and the Muscular Dystrophy Association today announced that $1 Million has been awarded for preclinical work in support of an Investigational New Drug application with the U.S. Food and Drug Administration for ARM210, a novel, orally available, small-molecule Rycal drug that has potential as a treatment for Duchenne muscular dystrophy.

18 Apr 2013

Findings hold promise for development of therapies to fight different viral infections

The human body has the ability to ward off viruses by activating a naturally occurring protein at the cellular level, setting off a chain reaction that disrupts the levels of cholesterol required in cell membranes to enable viruses to enter cells.

18 Apr 2013

Research sheds light on malaria-related parasite's transition from acute to chronic stage

A new discovery about the malaria-related parasite Toxoplasma gondii -- which can threaten babies, AIDS patients, the elderly and others with weakened immune function -- may help solve the mystery of how this single-celled parasite establishes life-long infections in people.

10 Apr 2013

Nobel Prize recipient describes on innate immunity at Annual Drosophila Research Conference

A young scientist's astute observation - that grasshoppers don't get sick - eventually led to profound insights into our own immunity.

6 Apr 2013

Study: Protein clumps in nerve cells are pathologies of Parkinson's disease

Clumps of α-synuclein protein in nerve cells are hallmarks of many degenerative brain diseases, most notably Parkinson's disease.

29 Mar 2013

Scientists discover new mechanism that regulates replication of insulin-producing beta cells in pancreas

Bringing scientists a step closer to new treatments for diabetes, researchers at the University of Pittsburgh School of Medicine and The Mount Sinai Medical Center have discovered a novel mechanism that regulates the replication of insulin-producing beta cells in the pancreas.

27 Mar 2013

German Research Foundation sets up eight new Research Units

The Deutsche Forschungsgemeinschaft is establishing eight new Research Units. This was decided by the DFG Senate during its 2013 March meeting in Bonn.

20 Mar 2013

MBL study of dragonfly prey detection wins 2012 Cozzarelli Prize for scientific excellence and originality

Paloma T. Gonzalez-Bellido, a postdoctoral scientist at the Marine Biological Laboratory and her colleagues have been awarded a 2012 Cozzarelli Prize by the editorial board of the Proceedings of the National Academy of Sciences.

16 Mar 2013

Previously unknown cell discovered in the urethra of mice

A recent study conducted by a group of German scientists revealed the presence of a previously unknown cell in the urethra of mice. These chemosensory cholinergic brush cells are in close contact to sensory neurons that express cholinergic receptors.

15 Mar 2013

Lack of very long chain fatty acids does not cause blindness in children with Stargardt type 3

Vision scientists long have thought that lack of very long chain fatty acids in photoreceptor cells caused blindness in children with Stargardt type 3 retinal degeneration, an incurable eye disease. But researchers at the University of Utah's John A. Moran Eye Center have shown in a new study that lack of these fatty acids does not cause blindness, meaning that the search for the mechanism that robs sight from children with the disease must start anew.

12 Mar 2013

Researchers discover how LRRK2 mutations in familial Parkinson's damage brain cells

Researchers at Columbia University Medical Center (CUMC), with collaborators at the Albert Einstein College of Medicine of Yeshiva University, have discovered how the most common genetic mutations in familial Parkinson's disease damage brain cells.

6 Mar 2013

New research examines role of PKC in airway smooth muscle contraction

New research examines the role of PKC in airway smooth muscle contraction and raises the possibility that this enzyme could be a therapeutic target for treating asthma, COPD, and other lung diseases.

26 Feb 2013

Antibody delivery system launched that works even in presence of additives

...

22 Feb 2013

Study finds new mutation in UBIAD1 gene that causes Schnyder corneal dystrophy

Research conducted by Dr. Jayne S. Weiss, Professor and Chair of Ophthalmology at LSU Health Sciences Center New Orleans, and colleagues has discovered a new mutation in a gene that causes Schnyder corneal dystrophy (SCD.)

22 Feb 2013

CB2 receptors might serve as potential therapeutic targets for cerebral ischemia

A new study published in the March issue of The American Journal of Pathology suggests that cortical type 2 cannabinoid (CB2) receptors might serve as potential therapeutic targets for cerebral ischemia.

22 Feb 2013

Researchers use familial and sporadic patient-derived iPSCs to model Alzheimer's disease

Working with a group from Nagasaki University, a research group at the Center for iPS Cell Research and Application (CiRA) at Japan's Kyoto University has announced in the Feb. 21 online publication of Cell Stem Cell has successfully modeled Alzheimer's disease (AD) using both familial and sporadic patient-derived induced pluripotent stem cells (iPSCs), and revealed stress phenotypes and differential drug responsiveness associated with intracellular amyloid beta oligomers in AD neurons and astrocytes.

21 Feb 2013

Daclatasvir has two primary modes of action against HCV

A study by researchers from Los Alamos National Laboratory and a multinational team reveals how daclatasvir, a direct-acting antiviral agent in development for the treatment of hepatitis C virus (HCV), targets one of its proteins and causes the fastest viral decline ever seen with anti-HCV drugs - within 12 hours of treatment.

21 Feb 2013

Intracellular News and Research

Cempra demonstrates solithromycin's potential against urogenital infections at ECCMID

GI nematode infections combat obesity and improve related metabolic disorders

UB researchers develop aniontransporters to trigger cancer cell apoptosis

ARMGO Pharma gets $1 million to support ARM210 preclinical work for DMD treatment

Findings hold promise for development of therapies to fight different viral infections

Research sheds light on malaria-related parasite's transition from acute to chronic stage

Nobel Prize recipient describes on innate immunity at Annual Drosophila Research Conference

Study: Protein clumps in nerve cells are pathologies of Parkinson's disease

Scientists discover new mechanism that regulates replication of insulin-producing beta cells in pancreas

German Research Foundation sets up eight new Research Units

MBL study of dragonfly prey detection wins 2012 Cozzarelli Prize for scientific excellence and originality

Previously unknown cell discovered in the urethra of mice

Lack of very long chain fatty acids does not cause blindness in children with Stargardt type 3

Researchers discover how LRRK2 mutations in familial Parkinson's damage brain cells

New research examines role of PKC in airway smooth muscle contraction

Antibody delivery system launched that works even in presence of additives

Study finds new mutation in UBIAD1 gene that causes Schnyder corneal dystrophy

CB2 receptors might serve as potential therapeutic targets for cerebral ischemia

Researchers use familial and sporadic patient-derived iPSCs to model Alzheimer's disease

Daclatasvir has two primary modes of action against HCV

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News