Ion News and Research

RSS

Researchers have identified the proteins that allow specific brain cells to "change channels"

Johns Hopkins researchers have identified the proteins that allow specific brain cells to "change channels," a rare ability that tweaks what can come into the cell. The findings, described in the March 24 issue of Neuron, might let researchers harness the process, perhaps one day using it to protect cells that die in Lou Gehrig's disease.

28 Mar 2005

Naturally occurring antifungal agent in saliva kills oral pathogen responsible for most HIV-related oral infections

Oral biologists at the University at Buffalo have shown for the first time how histatin, the naturally occurring antifungal agent in saliva, kills the oral pathogen Candida albicans, the fungus responsible for most HIV-related oral infections.

14 Mar 2005

Definitive evidence that TRPV3 is a temperature sensor

The human brain is like a general in a bunker. Floating in its bubble of cerebrospinal fluid, it has no direct window to the outside world, so the only way for the brain to observe, comprehend, and order the body into action is to rely on information it receives.

6 Mar 2005

Cellular porthole has a major role in helping the brain sense odors

A cellular "porthole" known best for its role in the digestive system apparently has a major role in helping the brain sense odors, Johns Hopkins scientists report in the Feb. 17 issue of Neuron. The porthole, which lets chloride into cells, is also critical in digestion, hearing, balance, and fertility.

27 Feb 2005

Claims about the experimental protein-based assay are not biologically plausible

In a new study, researchers present a "cautionary tale" about what may go wrong when using the fledgling science of proteomics to devise a diagnostic test for cancer.

15 Feb 2005

Research into foot-eye coordination

By measuring how people respond when a stepping stone suddenly shifts its position mid-step, researchers at the Institute of Neurology in London have shown that a powerful visual process controls the stepping foot – a process similar to that used for manual reaching, in which the hand is rapidly and automatically driven by visual information.

26 Jan 2005

Genetic defect leads to electrical instability and mechanical pump failure

In genetic mapping of a large family with several members affected by a type of heart failure called dilated cardiomyopathy (DCM), the Mayo Clinic team found a defect in a gene on chromosome 3 called SCN5A.

26 Jan 2005

Santa can do the job and Christmas is saved!

Calculations maintain that the laws of physics should prevent Santa Claus from delivering all his gifts and that Santa would burn up in the atmosphere if he tried. The internet magazine, forskning.no, has put together a team of four top researchers to look into the case. The panel’s conclusion is clear: Santa can do the job and Christmas is saved!

23 Dec 2004

The way the movies represent amnesia is profoundly misleading

Analyzing a host of movies from the silent era up to the present day, the paper traces a number of regular misconceptions about the condition.

20 Dec 2004

FDA accepts Genmab's Investigational New Drug Application for active rheumatoid arthritis treatment

Genmab announced today the US Food and Drug Administration (FDA) accepted its Investigational New Drug Application (IND) to start a Phase I/II dose escalation trial for HuMax-CD20 to treat patients with active rheumatoid arthritis (RA) who have failed one treatment with one or more disease modifying anti-rheumatic drugs (DMARDs).

13 Dec 2004

New advances in sickle cell disease

Excruciating pain episodes, recurrent pneumonias, strokes, severe infections, chronic hemolytic anemia, and secondary pulmonary hypertension are common complications of sickle cell disease, a life-threatening inherited defect in blood that causes normally disc-shaped red blood cells to take on a sickle shape.

6 Dec 2004

Temperature sensing protein implicated in mediating thermotaxis

The songwriter Noel Coward once declared that only mad dogs and Englishmen went out in the midday sun. MIT biologists Mark Rosenzweig, Paul Garrity and their colleagues now have a third candidate for the lyric—fruit flies with defects in a gene called dTrpA1.

4 Dec 2004

Scientists have given blind nerve cells the ability to detect light

Scientists at the University of California, Berkeley, have given "blind" nerve cells the ability to detect light, paving the way for an innovative therapy that could restore sight to those who have lost it through disease.

24 Nov 2004

World’s strongest acid may have a role in synthesizing pharmaceuticals

Researchers at the University of California, Riverside have discovered the world’s strongest acid. Remarkably it is also the gentlest acid. This non-toxic and non-corrosive acid may have a role in processes such as improving the quality of gasoline, developing polymers and synthesizing pharmaceuticals.

16 Nov 2004

Researchers have identified a protein that transports the essential nutrient boron into cells

Researchers at UT Southwestern Medical Center at Dallas have identified a protein that transports the essential nutrient boron into cells, where it is important for cell growth and bone development. The findings are in the Nov. 5 edition of the journal Molecular Cell and are online.

5 Nov 2004

Channeling through plasma to accelerate bright beams for science and medicine

Researchers at Lawrence Berkeley National Laboratory have produced high quality electron beams in an accelerating structure of only a few millimeters long.

4 Nov 2004

An errant enzyme linked to bipolar disorder impairs awareness, perception and reasoning

The disturbed thinking, impaired judgment, impulsivity, and distractibility seen in mania, a destructive phase of bipolar disorder, may be traceable to overactivity of protein kinase C (PKC), suggests the study, funded by the National Institute of Mental Health (NIMH) and National Institute on Aging (NIA), and the Stanley Foundation.

1 Nov 2004

New journal offering free access publishing and what is believed to be a unique development in the field of scientific publishing

Uniquely providing totally free access to scientific publications, and offering financial rewards for both authors and peer reviewers

19 Oct 2004

First sliver-sized sensor to monitor glucose level for diabetics and other bodily fluid levels

It's a good thing that the now eight-year-old son of Miklos Gratzl, a Case Western Reserve University biomedical engineer, got a splinter in his finger one day – at least for the sake of science. With apologies to his son – instead of an "Ouch!" moment, for Gratzl it was more of an "A-ha!" moment.

18 Oct 2004

Discovery might improve design, effectiveness of anti-cancer drugs

Working with an enzyme that degrades anti-cancer drugs in humans, University of North Carolina at Chapel Hill biochemists and colleagues have made a discovery that they believe eventually could help improve such drugs’ design and effectiveness.