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Metrion collaborates with LifeArc on neuroscience-focused ion channel drug discovery project

Metrion Biosciences and LifeArc have entered into a collaboration agreement for an ion channel drug discovery project in the field of neuroscience.

From Metrion Biosciences Limited 30 Jan 2019

How Patch Clamp Technology Can Benefit Ion Channel Research

Learn how patch clamp technology meets high-throughput to benefit ion channel research in this interview with Tim and James, Nanion.

From Nanion Technologies 16 Jan 2019

Investigational topical cream may be effective for treating atopic dermatitis

A study published in the British Journal of Dermatology indicates that an investigational nonsteroidal topical cream may be effective for treating atopic dermatitis, one of the most common inflammatory skin diseases.

9 Jan 2019

Researchers report novel findings on plant hormone

Jasmonic acid is not just the aromatic odor of the plant Jasminum grandiflorum used in cosmetics and perfume industries. Plants wounded by e.g. chewing herbivores produce jasmonic acid as a defense signal, as a phytohormone to mount their defense responses - this includes for example the formation of toxic substances.

10 Dec 2018

Researchers create new light-activated tools for controlling neurons

By enabling super-fast remote control of specific cells, light-activated proteins allow researchers to study the function of individual neurons within a large network - even an entire brain. Now one of the pioneers of 'optogenetics' and colleagues have created two new tools - protein pores which when illuminated allow Ca2+ into cells or K+ out - for switching neurons on or off using light.

6 Dec 2018

Scientists identify new drug target for potential blood pressure treatment

Scientists have identified a key player in blood pressure regulation and have shown that switching it off reduces blood pressure in mice, according to new research in eLife.

6 Dec 2018

Aurora Biomed organizes 2018 Shunde Biomedical Industry Investment Promotion Conference

From November 14-17, the "2018 Shunde Biomedical Industry Investment Promotion Conference" which ran in parallel with the Precision Medicine and Ion Channel Retreat was successfully held at the Ramada Plaza Hotel, Shunde, Guang Dong, China.

3 Dec 2018

Researchers elucidate central mechanisms of salt-induced hypertension through sympathetic activation

Hypertension is a major risk factor for cardiovascular disease worldwide, and approximately 40% (1 billion) of adults aged 25 and above have been diagnosed with hypertension. A positive correlation between salt intake and blood pressure has long been postulated.

30 Nov 2018

Insights from the Shunde Biomedical Industry Investment Promotion Conference

From November 14-17, the 2018 Shunde Biomedical Industry Investment Promotion Conference was successfully held at the Ramada Plaza Hotel, Shunde, GuangDong, China

From Aurora Biomed Inc. 29 Nov 2018

A Preclinical Solution to Studying Neurological Diseases

At SfN 2018, Antti Nurmi explained a case study of how Charles River have used neuroimaging to study Batten's Disease.

From Charles River Laboratories Neuroscience 26 Nov 2018

Silver nanoparticles coated with anti-seizure drugs can kill brain-eating amoebae

Halloween is just around the corner, and some people will celebrate by watching scary movies about brain-eating zombies.

24 Oct 2018

Human neurons employ highly compartmentalized signaling, study shows

Human neurons are much larger than those of model organisms mice and rats, so it's been unclear whether it's size that makes a difference in our brain's computational power.

19 Oct 2018

Researchers examine SSRI use during pregnancy and major gestational malformations

A comprehensive new review article presents the most current understanding of the role selective serotonin reuptake inhibitors play in increased risk of multiple diverse gestational malformations and takes aim at the ongoing debate over whether SSRIs as a drug class can cause these malformations.

16 Oct 2018

Researchers unravel fresh clues as to how kidney stones form

Kidney stones--solid, pebble-like grit that forms when too much of certain minerals like calcium are in the urine--can strike men, women, and increasingly, children, and the presence and pain of stones afflicts more than 12 percent of the world's population.

11 Oct 2018

Molecular mechanisms behind therapeutic action of ancient herbal medicine discovered

Researchers in the Department of Physiology & Biophysics at the University of California, Irvine School of Medicine have discovered the molecular basis for a therapeutic action of an ancient herbal medicine used across Africa to treat various illnesses, including epilepsy.

10 Oct 2018

Scientists identify new biomarker for Alzheimer's disease of sporadic origin

The objective of the research, undertaken in the laboratories of the IBPM, is to develop a model for studying Alzheimer's disease of sporadic origin, in other words, not due to a hereditary genetic mutation.

10 Oct 2018

Researchers show possibility to restore insulin cell function in type 2 diabetes

By blocking a protein, VDAC1, in the insulin-producing beta cells, it is possible to restore their normal function in case of type 2 diabetes. In preclinical experiments, the researchers behind a new study have also shown that it is possible to prevent the development of the disease.

8 Oct 2018

Study reveals structure of potential drug target in neurological conditions

Researchers at Van Andel Research Institute (VARI) have revealed the atomic-level structure of a protein that could serve as a promising new drug target for the treatment of neurological conditions such as bipolar disorder and Alzheimer’s disease.

25 Sep 2018

Inhaled form of high blood pressure drug has potential to treat anxiety, pain

An inhaled form of a high blood pressure medication has potential to treat certain types of anxiety as well as pain, according to a new study by the Centre for Addiction and Mental Health.

11 Sep 2018

Researchers reveal effect of high amounts of cholesterol on specific ion channel in heart

Using a computer model, researchers from North Carolina State University and the University of Illinois at Chicago have revealed the effect of increased amounts of cholesterol on a specific ion channel involved in regulating potassium levels in the heart.