Irinotecan News and Research

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Irinotecan hydrochloride is approved by the Food and Drug Administration (FDA) to be used with other drugs to treat colorectal cancer that has metastasized (spread to other parts of the body). It is also approved to treat metastatic colorectal cancer that has recurred (come back) or gotten worse after earlier chemotherapy. In addition to the uses that have been approved by the FDA, irinotecan hydrochloride is sometimes used to treat other types of cancer. Irinotecan hydrochloride is also being studied in the treatment of other types of cancer.
New insights on 5-fluorouracil's mechanism in different cancers

New insights on 5-fluorouracil's mechanism in different cancers

Immunotherapy-chemotherapy combo boosts survival for patients with metastatic colorectal cancer

Immunotherapy-chemotherapy combo boosts survival for patients with metastatic colorectal cancer

First UK real-world study shows promise for sacituzumab govitecan in metastatic breast cancer

First UK real-world study shows promise for sacituzumab govitecan in metastatic breast cancer

Novel treatment strategy shows promise against common liver cancer in children

Novel treatment strategy shows promise against common liver cancer in children

Children with neuroblastomas may benefit from new drug cocktail

Children with neuroblastomas may benefit from new drug cocktail

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

Exploring the link between drugs and microbiota: a growing imperative in precision medicine

Exploring the link between drugs and microbiota: a growing imperative in precision medicine

Amgen to discuss application for LUMAKRAS® (sotorasib) for the treatment of KRAS G12C-positive NSCLC at FDA advisory committee meeting

Amgen to discuss application for LUMAKRAS® (sotorasib) for the treatment of KRAS G12C-positive NSCLC at FDA advisory committee meeting

Epigenetic manipulation may improve breast cancer treatment responses

Epigenetic manipulation may improve breast cancer treatment responses

Experts develop commercial formulation Campto for colorectal cancer

Experts develop commercial formulation Campto for colorectal cancer

Chemotherapy in the afternoon proved to be effective for female lymphoma patients

Chemotherapy in the afternoon proved to be effective for female lymphoma patients

Chemotherapy schedule affects treatment outcomes in female DLBCL patients

Chemotherapy schedule affects treatment outcomes in female DLBCL patients

Four-drug chemotherapy regimen provides longer overall survival for metastatic pancreatic ductal adenocarcinoma

Four-drug chemotherapy regimen provides longer overall survival for metastatic pancreatic ductal adenocarcinoma

Research identifies unique vulnerabilities in ALT cancers that can serve as novel therapeutic targets

Research identifies unique vulnerabilities in ALT cancers that can serve as novel therapeutic targets

Biochemist finds new way to protect healthy leukocytes during chemotherapy

Biochemist finds new way to protect healthy leukocytes during chemotherapy

TTUHSC researcher secures $1.9 million grant to investigate vulnerabilities in ALT cancers

TTUHSC researcher secures $1.9 million grant to investigate vulnerabilities in ALT cancers

Reducing mucin secretion provides a way to control chemoresistance of colorectal cancers

Reducing mucin secretion provides a way to control chemoresistance of colorectal cancers

Researchers identify new drug that makes pancreatic cancer cells more vulnerable to chemotherapy

Researchers identify new drug that makes pancreatic cancer cells more vulnerable to chemotherapy

Researchers compare transcriptomic and cytokine responses of colorectal cancer cells

Researchers compare transcriptomic and cytokine responses of colorectal cancer cells

Topoisomerase 1 inhibition prevents SARS-CoV-2-induced inflammation and death in animal models

Topoisomerase 1 inhibition prevents SARS-CoV-2-induced inflammation and death in animal models

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