Kidney Failure News and Research

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Obesity related to kidney failure

Researchers at the University of California, San Francisco have determined that there is a strong relationship between being obese and developing end-stage renal disease, or kidney failure.

2 Jan 2006

Early, aggressive treatment of type 1 diabetes reduced risk heart disease and stroke

Intensive and early treatment of type 1 diabetes substantially lowers the risk of cardiovascular ailments such as heart disease and stroke, a new multicenter study shows.

22 Dec 2005

Cannabis medication linked to grandmother's death

A British grandmother who died after being given a controversial and experimental cannabis-based medicine had apparently told her family that she thought the drug was driving her mad.

19 Dec 2005

New findings in patients with pediatric kidney failure

Two studies just released by physicians at Texas Children's Hospital are addressing new findings in patients with pediatric kidney failure, and on the growing prevalence of high blood pressure in children.

28 Nov 2005

Thrombospondin (TSP-1) can cause kidney failure when normal blood flow is disrupted

Scientists led by a University of Cincinnati (UC) kidney expert have found that a naturally occurring protein that normally fights cancer cells can also cause severe kidney failure when normal blood flow is disrupted.

26 Nov 2005

High blood pressure research advances efforts to tailor drugs to individual patients

Having high blood pressure and a particular genetic alteration dramatically increases the risk of heart attack, stroke or death, and may explain why some hypertensive patients fare worse than others - even if they take the same medication, University of Florida researchers announced.

26 Nov 2005

Valproic acid (Depakote) may help treat lupus

A common anti-seizure drug may be effective against certain conditions associated with lupus, according to animal research at Wake Forest University School of Medicine.

20 Nov 2005

Edifoligide no better than placebo for clogged veins

A new drug, edifoligide, designed to prevent the clogging of veins used in coronary bypass surgery was no more effective than a placebo, according to the results of a Phase III clinical trial led by researchers at Duke Clinical Research Institute (DCRI).

14 Nov 2005

Lupus discovery may improve treatment

Researchers at Wake Forest University School of Medicine and the University of Virginia hope to reset part of the "epigenetic code" in lupus patients and thus improve treatment.

7 Nov 2005

Study proves the effectiveness of Vfend for the treatment of candidemia

Using Vfend (voriconazole) for the treatment of nonneutropenic patients with candidemia, an often-fatal hospital-acquired bloodstream infection, is as effective as a regimen of two older antifungals and carries fewer serious side effects than that regimen.

7 Nov 2005

Nearly one-fourth of all dialysis patients have a close relative on dialysis

Researchers at Wake Forest University Baptist Medical Center, and others, report in the current online edition of the American Journal of Nephrology. The researchers suggest screening other relatives for undetected kidney disease.

3 Nov 2005

As men grow older, bladder function can worsen and the prostate gland may be responsible

Their findings remind patients and their physicians that urination difficulties in men can be better cared for at early onset. Additionally, the study notes that as men age, the possibility increases that they will experience problems with urination.

25 Oct 2005

Rates for new cases of kidney failure have stabilized

After 20 years of annual increases from 5 to 10 percent, rates for new cases of kidney failure have stabilized, according to new research from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). At the same time, dramatic racial disparities persist.

11 Oct 2005

Tonsils reveal information that helps understand lupus

By snipping out and analyzing tiny samples of patients' tonsils, scientists have identified a key cellular checkpoint that is somehow bypassed in lupus patients, where harmful immune cells that normally are squelched by the body are mistakenly granted access.

9 Oct 2005

Amiloride and spironolactone may help patients with high blood pressure

Two inexpensive but widely overlooked drugs may help many patients who continue to have high blood pressure despite taking standard blood pressure medications, according to research by Indiana University School of Medicine scientists.

4 Oct 2005

Study paves the way for new therapeutic targets which can potentially improve heart disease in patients with end-stage kidney failure

Night-time hemodialysis patients may have a greater capacity to repair their hearts and blood vessels compared to those on conventional dialysis three times a week, according to a study in the October issue of the American Journal of Physiology - Renal Physiology, published by the American Physiological Society.

4 Oct 2005

Mayo Clinic researchers find earliest sign of nerve change due to diabetes

Mayo Clinic researchers have found that subtle change in nerve conduction is the first reliable sign of nerve complications from diabetes and that this change can be measured long before other symptoms or signs of nerve damage develop.

3 Oct 2005

Researchers map genetic location that explains why certain blood pressure-lowering drugs aren't effective for some people

"The findings bring us a step closer to developing targeted therapies for patients with high blood pressure who might otherwise be started on medications that won't help," said lead author Sandosh Padmanabhan, Ph.D.

26 Sep 2005

Key cellular switch that controls glucose production in liver cells

In many patients with type 2 diabetes, the liver acts like a sugar factory on overtime, churning out glucose throughout the day, even when blood sugar levels are high. Scientists at the Salk Institute for Biological Studies discovered a key cellular switch that controls glucose production in liver cells.

12 Sep 2005

Soldiers at risk for heat illnesses

A study reviewing 22 years of data on heat illness hospitalizations and deaths in the U.S. Army indicates soldiers remain at risk for exertional heat illness. While hospitalization rates for heat illnesses have declined over this period, cases of heat stroke have increased.

6 Sep 2005