Kidney Transplant News and Research

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A kidney transplant is an operation where a healthy kidney from one person (the donor) is transferred to a person who has little or no kidney function (the recipient).

Chronic kidney disease patients with depression have poorer health outcomes: Researchers

Patients with chronic kidney disease who have been diagnosed with depression are twice as likely to be hospitalized, progress to long-term dialysis treatments or die within a year as those who are not depressed, UT Southwestern Medical Center researchers have found.

20 May 2010

Immunosuppressive drug sirolimus improves kidney health of patients with ADPKD: Study

The immunosuppressive drug sirolimus considerably improves the kidney health of patients with autosomal dominant polycystic kidney disease, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.

14 May 2010

Steroids can raise cardiovascular risks in post-transplant patients

Post-transplant patients who have been removed from a corticosteroid regimen have fewer cardiovascular events than those patients on steroids, increasing their graft survival rates and reducing early mortality, according to study results being presented this week by University of Cincinnati (UC) transplantation researchers.

10 May 2010

Quark to present poster on predicting risk of DGF following machine perfusion of renal transplants at ATC 2010

Quark Pharmaceuticals, Inc., the world leader in clinical development of RNAi-based therapeutics, announced today the presentation of a poster at the 2010 American Transplant Congress titled, "A Nomogram for Predicting Risk of Delayed Graft Function Following Machine Perfusion of Renal Transplants."

5 May 2010

Argos Therapeutics announces presentations on sCD83 protein capabilities at 2010 American Transplant Congress

Argos Therapeutics today announced two oral presentations detailing data on its soluble CD83 (sCD83) protein program at the 2010 American Transplant Congress, held May 1-5 in San Diego. The data, which were produced by Argos in collaboration with scientists from the University of Western Ontario, demonstrate that sCD83 is capable of inducing immune system tolerance to transplant grafts and suppressing an anti-donor antibody response, via a multi-faceted mechanism-of-action that impacts B and T cells, as well as dendritic cells.

5 May 2010

Belatacept preserves kidney function in transplant recipients better than cyclosporine, says study

Two-year results from phase III clinical trials show the experimental immunosuppressive drug belatacept can better preserve kidney function in kidney transplant recipients while preventing graft rejection when compared with the standard immunosuppressive drug cyclosporine.

3 May 2010

FDA issues complete response letter for Bristol-Myers Squibb's belatacept

Bristol-Myers Squibb Company today announced that the U.S. Food and Drug Administration has issued a complete response letter regarding the Biologics License Application for belatacept in kidney transplantation.

3 May 2010

Heart and liver transplant recipients at higher risk of developing lung cancer: Researchers

Heart and liver transplant recipients are at particularly high risk of developing lung cancer after receiving the donated organ, researchers report at the 2nd European Lung Cancer Conference. They are advising doctors to screen for such cancers in these patients to maximize the chance of detecting the malignancy early.

3 May 2010

Kidney transplant recipients have higher risk of cancer: Researchers

Kidney transplant recipients are known to have a higher risk of cancer, compared to the general population, due to the need to take immunosuppressive drugs to prevent organ rejection. Results published today from a significant, long-term study suggest that no single medication appears to increase this cancer risk.

30 Apr 2010

No single immunosuppressive medication increases cancer risk in kidney transplant recipients

Drugs taken by kidney transplant recipients to prevent organ rejection carry similar risks of cancer, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The results suggest that no single medication is to blame for the higher incidence of cancer seen among patients who have undergone transplantation.

30 Apr 2010

States crack down on discount health plans

Kaiser Health News: "State regulators are cracking down on a health care product that targets the growing group of uninsured and underinsured Americans: the discount health plan.

30 Apr 2010

Bristol-Myers Squibb reports 11% increase in first-quarter 2010 revenue

Bristol-Myers Squibb Company today reported strong sales and earnings growth for the first quarter of 2010.

30 Apr 2010

6 transplant surgeons perform 16 surgeries over 3 days in landmark domino paired kidney exchange

Chicago resident Maria Isho had been waiting for over nine years for a kidney transplant. Her body was highly sensitized, meaning that her body had built up antibodies in the blood, which made it difficult for her to find a match. To stay healthy, she endured a grueling dialysis regimen which diminished her quality of life and left her feeling physically drained.

29 Apr 2010

Bristol-Myers Squibb to present on belatacept at American Transplant Congress

Bristol-Myers Squibb Company announced today that belatacept, an investigational selective T cell co-stimulation blocker being studied for use in solid organ transplantation, will be the subject of eight clinical presentations related to kidney transplantation at the American Transplant Congress, being held May 1 - 5 in San Diego.

29 Apr 2010

Alexion Pharmaceuticals reports total revenues of $117.6M from net product sales of Soliris

Alexion Pharmaceuticals, Inc. today announced financial results for the quarter ended March 31, 2010.

22 Apr 2010

FDA approves Novartis Pharmaceuticals' Zortress for preventing rejection of kidney transplants

The US Food and Drug Administration (FDA) has approved Zortress® (everolimus) oral tablets for the prevention of rejection of kidney transplants in adult patients at low-to-moderate immunologic risk. Zortress is to be given in combination with reduced doses of the calcineurin inhibitor (CNI) cyclosporine, as well as basiliximab and corticosteroids.

22 Apr 2010

Tips on how to live joyful life with a chronic disease now available in audio version

Award winning speaker and author Lori Hartwell today released a 6-CD unabridged set of her renowned book, Chronically Happy: Joyful Living in Spite of Chronic Illness, which relates her optimism for life despite living with kidney disease for over 40 years.

21 Apr 2010

End-of-life care documentation helps in emergency treatment decisions

When Heather Rubesch was a teenager, her aunt died in need of a kidney transplant. In later family discussions, Heather's mother, Linda, expressed some of her views about end-of-life care—for instance, her belief in organ donation.

19 Apr 2010

Kidney expert receives international award

Professor Jonathan Craig from the School of Public Health has been honoured for his contribution to the study of kidney disease. The US-based National Kidney Foundation awarded Professor Craig with its 2010 International Distinguished Medal, recognising outstanding accomplishments in the field of nephrology.

16 Apr 2010

Genes influence chronic kidney disease risk: Research

A team of researchers from the United States and Europe has identified more than a dozen genes that may play a role in the etiology of common forms of kidney disease. The team, known as the CKDGen Consortium, examined common variations in DNA sequences in more than 65,000 individuals of European descent. Common variations in several genes were found to be more frequent among people with poor kidney function or chronic kidney disease than in those with normal kidney function.

13 Apr 2010

Kidney Transplant News and Research

Further Reading

Chronic kidney disease patients with depression have poorer health outcomes: Researchers

Immunosuppressive drug sirolimus improves kidney health of patients with ADPKD: Study

Steroids can raise cardiovascular risks in post-transplant patients

Quark to present poster on predicting risk of DGF following machine perfusion of renal transplants at ATC 2010

Argos Therapeutics announces presentations on sCD83 protein capabilities at 2010 American Transplant Congress

Belatacept preserves kidney function in transplant recipients better than cyclosporine, says study

FDA issues complete response letter for Bristol-Myers Squibb's belatacept

Heart and liver transplant recipients at higher risk of developing lung cancer: Researchers

Kidney transplant recipients have higher risk of cancer: Researchers

No single immunosuppressive medication increases cancer risk in kidney transplant recipients

States crack down on discount health plans

Bristol-Myers Squibb reports 11% increase in first-quarter 2010 revenue

6 transplant surgeons perform 16 surgeries over 3 days in landmark domino paired kidney exchange

Bristol-Myers Squibb to present on belatacept at American Transplant Congress

Alexion Pharmaceuticals reports total revenues of $117.6M from net product sales of Soliris

FDA approves Novartis Pharmaceuticals' Zortress for preventing rejection of kidney transplants

Tips on how to live joyful life with a chronic disease now available in audio version

End-of-life care documentation helps in emergency treatment decisions

Kidney expert receives international award

Genes influence chronic kidney disease risk: Research

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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