Leukemia News and Research

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Leukemia (Leukaemia) is a cancer of the blood cells. It is the most common type of blood cancer and affects 10 times as many adults as children. Most people diagnosed with leukemia are over 50 years old. No one knows why some people develop leukemia and others do not. However, scientists have identified some risk factors for the disease. Most people who have known risk factors do not get leukemia, while many who do get the disease have none of these risk factors. During the early stages of leukemia, there may be no symptoms. Many of the symptoms of leukemia don't become apparent until a large number of normal blood cells are crowded out by leukemia cells.

Decoy receptor 3 expressed in rheumatic synovial fibroblasts protects the cells against Fas-induced apoptosis

A complex autoimmune disease, rheumatoid arthritis (RA) is characterized by chronic inflammation and progressive joint damage. This process begins with hyperplasia, or excessive increase in size and thickness, of synovial tissue. Along with provoking cartilage and bone destruction, this abnormal tissue growth is resistant to apoptosis, the natural cell death vital to the generation of healthy new cells.

30 Mar 2007

Discovery of new cell involved with cancer

Scientists have discovered a new type of cell that appears to play a role in the development of cancer – a highly volatile, precancerous stem cell that can either remain benign or become malignant, depending upon environmental cues.

14 Mar 2007

Disorderly protein brings order to cell division

The secret to the ability of a molecule critical for cell division to throw off the protein yoke that restrains its activity is the yoke itself - a disorderly molecule that seems to have a mind of its own, say investigators at St. Jude

13 Mar 2007

Study aims to find which breast cancer patients need chemotherapy

Most postmenopausal women with small breast tumors don't need chemotherapy to reduce their recurrence risk after lumpectomy.

13 Mar 2007

New discovery suggests novel methods for treating acute lymphoblastic leukemia

Investigators at St. Jude Children's Research Hospital have discovered previously unsuspected mutations that contribute to the formation of pediatric acute lymphoblastic leukemia (ALL), the most common cancer in children.

8 Mar 2007

Novartis to continue Indian patent fight

Novartis CEO Daniel Vasella on Tuesday at the company's annual general meeting said that the drug maker plans to continue a lawsuit challenging a section of India's Patents Act that aims to restrict certain kinds of patents, despite criticism from some HIV/AIDS advocacy groups and shareholders, Reuters reports

8 Mar 2007

Perfluorocarbon nanoparticles track living cells

Stem cell therapy, primarily bone marrow transplantation, plays a key role in treating leukemia and other types of cancer.

26 Feb 2007

Old drug pentylenetetrazole may improve learning and memory in Down syndrome victims

Researchers in the United States have discovered that an old drug once used to study epilepsy substantially improved learning and memory in mice with Down syndrome symptoms.

26 Feb 2007

Determinants of disease presentation and outcome during cryptococcosis

CRNS and the Institut Pasteur conducted research in France on patients diagnosed with cryptococcosis which ranks second among fatal opportunistic infections in patients infected by HIV and who are profoundly immunosuppressed.

12 Feb 2007

Rate of stem cell transplants among African-Americans lower

Lower transplant rates in ethnic communities may be explained somewhat by a lack of suitable anonymous donors, a problem the medical community has long known and been working to address. Surprisingly, the study found the discrepancy in treatment held true even when the transplant was autologous (e.g. self-donated stem cells were used) or when the cells were donated by a relative, typically a sibling.

11 Feb 2007

Single transcription factor GABP a major player in cell growth

When cells go about the business of dividing, they can get sidelined. Maybe there aren't enough nutrients. Maybe there aren't the right signals to resume multiplying. Either way, cells go quiet.

7 Feb 2007

Scientists discover how T-cell leukemia viruses evade defense mechanisms

National Cancer Institute (NCI) scientists have discovered how human T-cell leukemia virus type 1 (HTLV-1), which infects about 20 million people worldwide, evades being held in check by one of the body's natural defense mechanisms.

6 Feb 2007

Discovery of pancreatic cancer stem cells could lead to more effective therapies

Scientists in the United States have identified for the first time the stem cells linked to pancreatic cancer.

1 Feb 2007

Scientists test technique for identifying newly recognized DNA variations that may influence disease risk

Rather than focus on errors and alterations in DNA sequence, the new technique highlights variations in the number of copies of a particular gene.

30 Jan 2007

Novartis' day in court could leave millions without AIDS drugs

The Swiss pharmaceutical giant Novartis is in court in India this week challenging the country's patent laws.

30 Jan 2007

FoxOs shown to be potential new targets for cancer drugs

In an elegant, multiple-gene knockout experiment, a team of Boston scientists has discovered that a trio of molecules, called FoxOs, are fundamentally critical in preventing some cancers, maintaining blood vessel stability, and in keeping blood-forming stem cells healthy.

29 Jan 2007

Disorderly protein brings order to cell division

The secret to the ability of a molecule critical for cell division to throw off the protein yoke that restrains its activity is the yoke itself a disorderly molecule that seems to have a mind of its own, say investigators at St. Jude Children's Research Hospital, Innsbruck Medical University and Max Planck Institute.

28 Jan 2007