Lipogenesis News and Research

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Lipogenesis is the process by which simple sugars such as glucose are converted to fatty acids, which are subsequently esterified with glycerol to form the triacylglycerols that are packaged in VLDL and secreted from the liver.

New findings offer pathway for fight against non-alcoholic fatty liver disease

A research group from the Medical University of Vienna was able to decode the mechanism as to how the hormone Leptin stimulates the liver to export lipids and reduce the fat production in the liver.

21 Jun 2019

Physical exercise can reduce liver fat, improve blood sugar control in obese individuals

Research conducted at the University of Campinas in São Paulo State, Brazil, shows that vigorous physical exercise such as strength and weight training can reduce accumulated liver fat and improve blood sugar control in obese and diabetic individuals in a short time span, even before significant weight loss occurs.

13 Jun 2019

The endocannabinoid system and skin conditions

a significant amount of research over the past 20 years has demonstrated that the endocannabinoid system plays a vital role in skin homeostasis, and therefore skin conditions too.

7 May 2019

Caspase-2 enzyme inhibitor could provide effective way to stop aggressive fatty liver disease

Researchers at University of California San Diego School of Medicine have discovered using mice and human clinical specimens, that caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis, a chronic and aggressive liver condition.

14 Sep 2018

Specific protein promotes processes associated with cancer aggressiveness, reports study

Japanese researchers have revealed for the first time that a specific protein plays a critical role in the development and metastasis of highly aggressive prostate and breast cancer cells.

31 Aug 2018

Scientists clarify casual role of oxidative stress in metabolically abnormal and healthy obesities

Scientists at Osaka University clarified that deletion of adipose oxidative stress (Fat ROS) decreased lipid accumulation in the liver, clinically improving insulin resistance and inducing metabolically healthy obesity.

25 Apr 2018

Fight for Sight awards new grants for 13 vital eye research projects

Fight for Sight, the leading eye research charity, has awarded grants totaling over £180,000 for thirteen vital research projects in partnership with nine different organizations.

2 Feb 2018

Research sheds new light on genetic, environmental factors that promote prostate cancer metastasis

Prostate tumors tend to be what scientists call "indolent" - so slow-growing and self-contained that many affected men die with prostate cancer, not of it. But for the percentage of men whose prostate tumors metastasize, the disease is invariably fatal.

15 Jan 2018

New oncogene may contribute to high incidence of prostate cancer among African American men

A team of scientists has identified MNX1 as a new oncogene - a gene than can cause cancer - that is more active in African American prostate cancer than in European American prostate cancer.

21 Oct 2016

Overweight kidney cancer patients live longer than normal-weight counterparts, study shows

Obesity almost always increases cancer risk and worsens outcomes, but researchers led by scientists at Dana-Farber Cancer Institute report that overweight patients with advanced kidney cancer had significantly longer survival than those who were normal or underweight.

6 Sep 2016

SLU researchers find way to stop growth of cancer cells by targeting the Warburg Effect

In research published in Cancer Cell, Thomas Burris, Ph.D., chair of pharmacology and physiology at Saint Louis University, has, for the first time, found a way to stop cancer cell growth by targeting the Warburg Effect, a trait of cancer cell metabolism that scientists have been eager to exploit.

26 Jun 2015

SLU researchers halt fatty liver disease in animal model

Doctors believe that up to 30 percent of the U.S. population may have fat accumulation in the liver, known as non-alcoholic fatty liver disease (NAFLD), that can lead to a range of damaging health consequences.

18 Feb 2015

UT Southwestern researchers discover crucial link between high insulin levels and obesity pathways

UT Southwestern Medical Center researchers have identified a crucial link between high levels of insulin and pathways that lead to obesity, a finding that may have important implications when treating diabetes.

26 Aug 2014

Researchers find way to prevent nonalcoholic fatty liver disease

Studying mice, researchers have found a way to prevent nonalcoholic fatty liver disease, the most common cause of chronic liver disease worldwide.

4 Jun 2014

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

Researchers have discovered a link between prostate cancer aggressiveness and the accumulation of a compound produced when cholesterol is metabolized in cells, findings that could bring new diagnostic and treatment methods.

5 Mar 2014

TSC22D4 gene plays a key role in the onset of cachexia

Cachexia or wasting is a condition affecting up to 70 percent of cancer patients, depending on the type of cancer. It is characterized by a dramatic loss of body weight that is independent of food intake. Cachexia is seen particularly often and most pronounced in patients suffering from cancers of the digestive tract and the lungs.

16 Jan 2013

Lipogenesis News and Research

Further Reading

New findings offer pathway for fight against non-alcoholic fatty liver disease

Physical exercise can reduce liver fat, improve blood sugar control in obese individuals

The endocannabinoid system and skin conditions

Caspase-2 enzyme inhibitor could provide effective way to stop aggressive fatty liver disease

Specific protein promotes processes associated with cancer aggressiveness, reports study

Scientists clarify casual role of oxidative stress in metabolically abnormal and healthy obesities

Fight for Sight awards new grants for 13 vital eye research projects

Research sheds new light on genetic, environmental factors that promote prostate cancer metastasis

New oncogene may contribute to high incidence of prostate cancer among African American men

Overweight kidney cancer patients live longer than normal-weight counterparts, study shows

SLU researchers find way to stop growth of cancer cells by targeting the Warburg Effect

SLU researchers halt fatty liver disease in animal model

UT Southwestern researchers discover crucial link between high insulin levels and obesity pathways

Researchers find way to prevent nonalcoholic fatty liver disease

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

TSC22D4 gene plays a key role in the onset of cachexia

New diagnostic tool identifies metastatic ability of breast cancer cells

Fatty acid synthase provides new target for treatment of obesity and diabetes

Metformin prevents primary liver cancer in animal models

Both absence of insulin and resistance to insulin are associated with defects in FAS

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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