Liquid Chromatography News and Research

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Advion introduces high performance liquid chromatography to complement its CMS

Advion, Inc., a leading systems and consumables developer for the life sciences industry, introduces an affordable high performance liquid chromatography system to complement its line of expression compact mass spectrometers (CMS). Introduced in 2012, the CMS has been met with glowing reviews from the global synthetic organic chemistry market. With hundreds of CMS purchased and installed, this latest introduction offers a complete solution for those needing separation capabilities at an affordable price.

From Advion 7 Aug 2014

Zhichan decoction promotes dopaminergic neurons following NSC transplantation in PD rats

There is an increasing interest in Parkinson's disease (PD) treatment by increasing dopamine content and reducing dopaminergic metabolites in the brain.

17 Jul 2014

Researchers develop new way to identify potential therapeutic targets for drug resistant melanoma

Moffitt Cancer Center researchers developed a new way to identify possible therapeutic targets for patients with drug resistant melanoma. It involves using liquid chromatography-multiple reaction monitoring mass spectrometry to measure biomarkers or molecules in blood and tissue that indicates cancer is present. These measurements can help researchers determine if a patient is responding to treatment.

1 Jul 2014

Backpack-sized device can perform highly accurate and sensitive cocaine testing in 15 minutes

Testing for cocaine and other drugs usually involves two steps: a quick on-site prescreen, and then a more accurate confirmatory test at a distant laboratory.

26 Jun 2014

Urine test separates nonadherent from treatment-resistant hypertensive patients

Researchers have used a urine test to show that about a quarter of patients with supposedly treatment-resistant hypertension are actually failing to take their medications as prescribed.

22 Apr 2014

Princeton professor receives Agilent Thought Leader Award to research on cellular metabolism activity

Agilent Technologies Inc. today announced that Joshua Rabinowitz, M.D., Ph.D., professor at Princeton University's Department of Chemistry and the Lewis-Sigler Institute for Integrative Genomics, has received an Agilent Thought Leader Award to support his work on quantitative analysis of cellular metabolism.

18 Apr 2014

Bruker releases application note for detection of pharmaceutical and personal care products in water using EVOQ LC-MS/MS

Bruker has released an application note detailing a simple and convenient method for the quantification of trace pharmaceutical and personal care products (PPCPs) in clean water, using Bruker’s EVOQ triple quadrupole liquid chromatography mass spectrometer (LC-MS/MS). PPCPs are products used for personal health or cosmetic reasons.

13 Mar 2014

Agilent and CambTEK partner to co-market RES automated sample preparation technology

Agilent Technologies Inc. (NYSE:A) and CambTEK, Ltd. today announced an agreement to co-market CambTEK's Rapid Extraction System (RES) automated sample preparation technology with an assortment of Agilent's liquid phase separation, life science and chemical analysis instruments and software.

26 Feb 2014

Researchers use new tools to measure and track B-12 vitamins in the ocean

The phrase, 'Eat your vitamins,' applies to marine animals just like humans. Many vitamins, including B-12, are elusive in the ocean environment.

25 Feb 2014

New halal testing method for detecting pig and horse contamination of meat

The mislabeling of meat products sold for human consumption has serious implications from a safety and ethical perspective. With recent news stories of pork and horsemeat contamination in different parts of the world, a renewed need for specialized testing of the food supply has rapidly arisen.

28 Jan 2014

Scientists obtain detailed molecular structure of member of Tet family of enzymes

Scientists have obtained the first detailed molecular structure of a member of the Tet family of enzymes.

28 Dec 2013

International researchers study glycans that could help clinicians diagnose gastric cancer early

Gastric cancer kills more than 700,000 people each year, mostly in Latin America, Asia and Eastern Europe. Though the disease is quite treatable when caught early, symptoms are indistinct and late detection leads to high mortality. The five-year survival rate in the United States is 26.9 percent.

22 Dec 2013

AB SCIEX launches IVD-MS Analyzer CE marked for general in vitro diagnostic use in Europe

Continuing to rapidly expand its presence in the clinical diagnostics field, AB SCIEX, a global leader in analytical technologies, today announced the launch of its AB SCIEX IVD-MS™ Analyzer CE marked for general in vitro diagnostic use in Europe.*

27 Nov 2013

Staphylococcus Aureus Bacteria anticipates and turns immune defenses against the host

Around 20 percent of all humans are persistently colonized with Staphylococcus aureus bacteria, a leading cause of skin infections and one of the major sources of hospital-acquired infections, including the antibiotic-resistant strain MRSA.

20 Nov 2013

Analysis of carbendazim in orange juice and wine

Bruker has released an application note on the evaluation of matrix effects on the analysis of carbendazim in orange juice and wine using the EVOQ Elite liquid chromatography mass spectrometer (LC-MS/MS). Carbendazim is a fungicide and a known endocrine with potentially harmful effects on human health.

From Bruker 13 Nov 2013

Scientists from University of Salzburg, Sandoz Pharmaceuticals and Thermo Fisher Scientific collaborate to advance protein-based pharmaceutical development

The Christian Doppler Laboratory for Biosimilar Characterization is now open at the Paris-Lodron University of Salzburg, and scientists there have commenced developing new methods for characterizing proteins to be used in biopharmaceuticals.

23 Oct 2013

Scientists identify dangerous amount of methamphetamine analog in workout supplement Craze

An international team of scientists have identified potentially dangerous amounts of methamphetamine analog in the workout supplement Craze, a product widely sold across the U.S. and online.

15 Oct 2013

Retinitis pigmentosa test identifies mutation found in Ashkenazi Jewish population

You might not think to look to a urine test to diagnose an eye disease. But a new Duke University study says it can link what is in a patient's urine to gene mutations that cause retinitis pigmentosa, or RP, an inherited, degenerative disease that results in severe vision impairment and often blindness. The findings appear online in the Journal of Lipid Research.

9 Oct 2013

Human Urine Metabolome Study Envisions New Diagnostic Era

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6 Sep 2013

More than 3,000 chemicals or "metabolites" can be detected in urine, say researchers

Researchers at the University of Alberta announced today that they have determined the chemical composition of human urine. The study, which took more than seven years and involved a team of nearly 20 researchers, has revealed that more than 3,000 chemicals or "metabolites" can be detected in urine.