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CRISPR revolutionized: New method edits genes directly in the body

Most approved gene therapies today, including those involving CRISPR-Cas9, work their magic on cells removed from the body, after which the edited cells are returned to the patient.

1 Feb 2024

Circulatory cholesterol levels are inversely linked to mortality of patients with sepsis and critical illness

The association between biomarkers of cholesterol homeostasis and mortality in critically ill patients.

1 Feb 2024

Is there an association between vitamin D, immunocompetence, and aging?

The role of an individual’s immunocompetence in the responsiveness to vitamin D.

1 Feb 2024

Study: Up to 10% of dementia cases in veterans may be caused by liver disease

As many as 10% of older U.S. veterans diagnosed with dementia may suffer instead from reversible cognitive decline caused by advanced liver disease, according to an analysis from the Virginia Commonwealth University's School of Medicine and the Richmond VA Medical Center.

31 Jan 2024

Researchers detect genetic traces of hepatitis E viruses in wastewater

Researchers have identified genetic traces of hepatitis E viruses in almost 73 percent of wastewater samples from North-Rhine Westphalia.

31 Jan 2024

Study reveals key mechanism behind obesity-related metabolic dysfunction

Researchers found that feeding a high-fat diet (HFD) causes mitochondrial dysfunction and fragmentation in white adipocytes in mice.

31 Jan 2024

Overcoming stigma to start early conversations about cognitive decline

Approximately four of five primary care clinicians consider themselves on the front lines of brain health.

30 Jan 2024

Study reveals significant health benefits of golden berries in diabetic and obese rats

The effects of a Golden Berry (Physalis peruviana)-enriched diet on insulin resistance and obesity.

30 Jan 2024

Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

A team of clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS), Agency for Science, Technology and Research (A*STAR), the Harry Perkins Institute of Medical Research and global research partners, has found a causal link between the presence of oncofetal ecosystems (re-emergence of fetal programme/features driven by the tumor) in the primary liver cancer hepatocellular carcinoma (HCC) and cancer recurrence and response to immunotherapy.

29 Jan 2024

Scientists reveal direct link between mitochondrial DNA mutations and cancer treatment response

Cancer Research UK-funded scientists have made an unusual discovery that could help to identify patients who are up to two and a half times more likely to respond to currently available cancer drugs.

29 Jan 2024

Liver fibrosis scores couldbe used for predicting adverse outcomes in patients with STEMI

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Liver fibrosis scores (LFSs) are novel tools for predicting cardiovascular events in patients with coronary artery disease.

29 Jan 2024

Dr. Chao Ma: Pioneering 'Leukemia-on-a-Chip' for CAR T Cell Therapy at SLAS 2024

NewsMedical speaks with Chao Ma, Ph.D. a Research Assistant Professor at New York University Tandon School of Engineering, ahead of his presentation at SLAS 2024.

From Society for Laboratory Automation and Screening (SLAS) 29 Jan 2024

Prime editing takes gene therapy to the next level

This study is led by Prof. Xianqun Fan (Department of Ophthalmology, Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital).

27 Jan 2024

Noninvasive diagnostic tool for identification of NASH by visualizing hepatic steatosis and inflammation

Non-alcoholic fatty liver disease (NAFLD), recently renamed metabolic dysfunction-associated fatty liver disease (MAFLD), is spectrum of diseases that ranges from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH).

26 Jan 2024

Mount Sinai project receives $4M grant to understand the early stages of Crohn's disease

The Icahn School of Medicine at Mount Sinai has been awarded a grant of more than $4 million from The Leona M. and Harry B. Helmsley Charitable Trust to support an innovative research project aimed at understanding the early stages of Crohn's disease before noticeable symptoms develop.

25 Jan 2024

Scientific review explores adzuki beans' efficacy in diabetes prevention and management

Adzuki bean (Vigna angularis) supplementation to prevent and manage type 2 diabetes (T2D).

25 Jan 2024

Balancing efficacy and safety: The challenges of mRNA drugs and vaccines in modern medicine

Researchers analyzed the toxicity concerns and advancements in mRNA therapeutics, focusing on their cellular toxicity, reactogenicity, and distribution, and discussed the challenges and benefits of mRNA research.

24 Jan 2024

NHS health checks linked to reduced risk of heart, brain, kidney, and liver diseases

A study analyzing UK Biobank data found that individuals who underwent the NHS health evaluation had a lower long-term risk of various diseases and mortality compared to those who did not participate in the assessment.

24 Jan 2024

RNA Therapies in Liver Disease: Insights from Ochre Bio's CEO

In this interview, we speak with Jack O'Meara, co-founder and CEO of Ochre Bio, a pioneering force in liver disease treatment. O'Meara shares insights into Ochre Bio's innovative RNA therapies, their approach to tackling liver disease, and the company's vision for the future.

24 Jan 2024

CN Bio and Altis Biosystems partner to develop next-generation human Gut/Liver in vitro model for advanced ADME studies

CN Bio and Altis Biosystems, Inc. (“Altis”), leading developers of in vitro human organ models that optimize the accuracy and efficiency of drug development, today announced a strategic partnership.

24 Jan 2024

Liver News and Research

CRISPR revolutionized: New method edits genes directly in the body

Circulatory cholesterol levels are inversely linked to mortality of patients with sepsis and critical illness

Is there an association between vitamin D, immunocompetence, and aging?

Study: Up to 10% of dementia cases in veterans may be caused by liver disease

Researchers detect genetic traces of hepatitis E viruses in wastewater

Study reveals key mechanism behind obesity-related metabolic dysfunction

Overcoming stigma to start early conversations about cognitive decline

Study reveals significant health benefits of golden berries in diabetic and obese rats

Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

Scientists reveal direct link between mitochondrial DNA mutations and cancer treatment response

Liver fibrosis scores couldbe used for predicting adverse outcomes in patients with STEMI

Dr. Chao Ma: Pioneering 'Leukemia-on-a-Chip' for CAR T Cell Therapy at SLAS 2024

Prime editing takes gene therapy to the next level

Noninvasive diagnostic tool for identification of NASH by visualizing hepatic steatosis and inflammation

Mount Sinai project receives $4M grant to understand the early stages of Crohn's disease

Scientific review explores adzuki beans' efficacy in diabetes prevention and management

Balancing efficacy and safety: The challenges of mRNA drugs and vaccines in modern medicine

NHS health checks linked to reduced risk of heart, brain, kidney, and liver diseases

RNA Therapies in Liver Disease: Insights from Ochre Bio's CEO

CN Bio and Altis Biosystems partner to develop next-generation human Gut/Liver in vitro model for advanced ADME studies

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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