Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Extracts made from herbs may improve learning and memory, study finds

Enhanced extracts made from special antioxidants in spearmint and rosemary improve learning and memory, a study in an animal model at Saint Louis University found.

15 Nov 2013

Promethera Biosciences completes patient enrolment for first clinical trial of HepaStem

Promethera Biosciences, a Belgian biotechnology company developing Promethera HepaStem, a cell-based therapy for the treatment of liver-based metabolic diseases including Crigler-Najjar Syndrome and Urea Cycle Disorders, announces today the completion of patient enrolment for its first clinical trial.

12 Nov 2013

Broom offers tips to help children cope with parent's deployment

While in the Navy, Broom regularly saw children of deployed parents in military pediatric offices. His biggest take away message from that experience is that families who are most successful at navigating deployment are those who plan and communicate.

12 Nov 2013

FOXO3 transcription factor may protect against alcohol-induced liver injury

New data suggest that the transcription factor FOXO3 may protect against alcohol-induced liver injury. Researchers determined that alcohol given to mice deficient in FOXO3 caused severe liver injury resembling human alcoholic hepatitis.

11 Nov 2013

Scientist shows how immune system 'attacks' liver cells during hepatitis by using JunB gene

Viral infections are the primary cause of liver inflammation or hepatitis, affecting hundreds of millions of people all over the world, and they represent a public health problem worldwide.

10 Nov 2013

Aerobic exercise may be superior to resistance exercise for obese teen girls

Obesity has more than doubled in children and tripled in adolescents in the United States in the past 30 years, according to the Centers for Disease Control and Prevention. The growing rate of childhood obesity is a major health concern since overweight and obese youth are at increased risk of developing several diseases once considered reserved for adults. These new pediatric diseases include type-2 diabetes, metabolic syndrome, and non-alcoholic fatty liver disease, a condition in which fat builds up in the liver, potentially impairing its function over time.

8 Nov 2013

Linagliptin shows efficacy, tolerability in adults with T2D and liver disease

Boehringer Ingelheim and Eli Lilly and Company announce new data that reinforce the efficacy and tolerability of linagliptin in people with Type 2 Diabetes and liver disease, as well as Asian people with T2D aged 65 years or older.

7 Nov 2013

Researchers, clinicians discuss recent findings that could bring hope for people with HIV

Since the onset of the AIDS pandemic more than three decades ago, researchers from the lab and physicians in the clinic have been working toward one shared goal: an AIDS-free world. This week, a conference hosted by the journals Cell and The Lancet brought leading researchers and clinicians together to discuss recent findings that could bring hope to the estimated 35 million people world-wide who live with HIV.

7 Nov 2013

Pivotal Phase III STARTVerso data shows efficacy of faldaprevir in genotype-1 infected HCV patients

Boehringer Ingelheim today announced new data from its Phase III clinical trial programme, STARTVerso, which evaluates faldaprevir in combination with pegylated interferon and ribavirin (PegIFN/RBV).

5 Nov 2013

Most severely obese teenagers who underwent bariatric WLS experience no major complications

Most severely obese teenagers who underwent bariatric weight-loss surgery (WLS) experienced no major complications, according to a study published by JAMA Pediatrics, a JAMA Network publication.

5 Nov 2013

Generic drug gabapentin appears to be safe, effective in treating alcohol dependence

The generic drug gabapentin, which is already widely prescribed for epilepsy and some kinds of pain, appears to be safe and effective in the treatment of alcohol dependence. The finding comes from a 150-patient randomized, placebo-controlled, double blind clinical trial conducted by scientists at The Scripps Research Institute.

4 Nov 2013

Boehringer Ingelheim's Phase II trial of interferon-free hepatitis C treatment shows promising results

Interim data presented today show that all patients (13/13) who reached their 4-week post-treatment follow-up have undetectable levels of hepatitis C virus (SVR4) after completing a 12-week regimen of faldaprevir, deleobuvir, PPI-668 and ribavirin.

4 Nov 2013

Study: Sugar intake is not directly associated with nonalcoholic fatty liver disease

Despite current beliefs, sugar intake is not directly associated with nonalcoholic fatty liver disease, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. Rather, high-calorie diets promote the progression of this serious form of liver disease.

4 Nov 2013

NIH selects two leading researchers to chair panels at geroscience symposium

The National Institutes of Health (NIH) has chosen two leading aging researchers at Albert Einstein College of Medicine of Yeshiva University to chair panels at the first symposium on "geroscience"-the study of how aging influences the onset of chronic diseases.

30 Oct 2013

Protective effect of estrogen in women with NASH against development of severe fibrosis

New research suggests that estrogen protects women with nonalcoholic steatohepatitis (NASH) from severe liver fibrosis. According to the study published online in Hepatology, a journal of the American Association for the Study of Liver Diseases, men are at higher risk of more severe fibrosis compared to women prior to menopause, but liver fibrosis severity is similar in men and post-menopausal women.

30 Oct 2013

Study: Investigational drug shows promise against pancreatic cancer

An investigational drug that disrupts tumor blood vessels shows promise against a rare type of pancreatic cancer, scientists at Albert Einstein College of Medicine of Yeshiva University have found. Their results were presented October 20 during a poster session at an international cancer conference.

25 Oct 2013

UHN, Boehringer Ingelheim partner to improve care, education and support for hepatitis C patients

In a move to address a significant unmet need in hepatitis C in Canada, the University Health Network, together with Boehringer Ingelheim (Canada) Ltd., announced today a multi-year partnership that aims to improve care, education and support for patients with hepatitis C. The program, known as Link-C, aims to improve access to hepatitis C care and treatment in remote areas of Ontario and other parts of Canada.

23 Oct 2013

Liver Disease News and Research

Further Reading

Extracts made from herbs may improve learning and memory, study finds

Promethera Biosciences completes patient enrolment for first clinical trial of HepaStem

Broom offers tips to help children cope with parent's deployment

FOXO3 transcription factor may protect against alcohol-induced liver injury

Scientist shows how immune system 'attacks' liver cells during hepatitis by using JunB gene

Aerobic exercise may be superior to resistance exercise for obese teen girls

Linagliptin shows efficacy, tolerability in adults with T2D and liver disease

Researchers, clinicians discuss recent findings that could bring hope for people with HIV

Pivotal Phase III STARTVerso data shows efficacy of faldaprevir in genotype-1 infected HCV patients

Most severely obese teenagers who underwent bariatric WLS experience no major complications

Generic drug gabapentin appears to be safe, effective in treating alcohol dependence

Boehringer Ingelheim's Phase II trial of interferon-free hepatitis C treatment shows promising results

Study: Sugar intake is not directly associated with nonalcoholic fatty liver disease

NIH selects two leading researchers to chair panels at geroscience symposium

Protective effect of estrogen in women with NASH against development of severe fibrosis

Study: Investigational drug shows promise against pancreatic cancer

UHN, Boehringer Ingelheim partner to improve care, education and support for hepatitis C patients

FDA grants Breakthrough Therapy designation to MK-5172/MK-8742 for chronic HCV infection

Einstein researchers receive $2.8M grant to focus on vexing question related to aging and cancer risk

Inovio Pharmaceuticals begins phase I clinical trial for hepatitis C vaccine

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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