Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

EpiCept and GNI partner to develop anti-viral hepatitis drug in Asia

GNI Ltd and EpiCept Corporation have announced that they have reached agreement to develop a new therapeutic drug, EP1013, in Asia, Australia, and New Zealand, for late-stage viral infection-induced hepatitis. EpiCept will retain the rights in the rest of the world. GNI’s wholly owned subsidiary, Shanghai Genomics, will start preparation for pre-IND and clinical development in China immediately.

17 Jul 2008

Enzyme may explain how hepatitis C infection causes fatty liver

A key enzyme may explain how hepatitis C infection causes fatty liver - a buildup of excess fat in the liver, which can lead to life-threatening diseases such as cirrhosis and liver cancer, report University of Pittsburgh Graduate School of Public Health and School of Medicine researchers.

10 Jul 2008

Fatty liver disease may raise heart disease risk in overweight, obese kids

A fatty liver disease that is not well-known in overweight and obese children may be a precursor of cardiovascular disease, researchers reported in Circulation: Journal of the American Heart Association.

30 Jun 2008

Drink up that coffee to reduce your risk of a heart attack!

According to new research drinking coffee on a long-term basis does not increase the risk of early death and may in fact reduce the risk of dying from heart disease.

17 Jun 2008

Age-adjusted death rates in U.S. down sharply in 2006

Age-adjusted death rates in the United States dropped significantly between 2005 and 2006 and life expectancy hit another record high, according to preliminary death statistics released today by CDC's National Center for Health Statistics.

11 Jun 2008

More aggressive hospital care does not lead to improved patient outcomes in all cases, study finds

More aggressive hospital care -- such as higher numbers of tests and procedures and longer stays -- does not lead to improved patient outcomes in all cases, according to a study released on Thursday, the Seattle Post-Intelligencer reports.

30 May 2008

Sea buckthorn berries may ward off liver disease

Sea buckthorn (Hippophae rhamnoides) berries are well known for their cholesterol busting properties, but scientists in India say that its leaves are also rich in anti-oxidants and may help ward off liver disease, according to new research due to be published in the Society of Chemical Industry's (SCI) Journal of the Science of Food and Agriculture.

25 May 2008

Think before you drink, says University research

People are being urged to think before they drink as part of a research project aimed at changing people's binge drinking habits.

12 May 2008

Hepatitis C therapy peginterferon alfa-2b shows promise

The hepatitis C therapy peginterferon alfa-2b, when given as low-dose maintenance therapy, can prevent disease progression in certain patients who failed previous interferon-based hepatitis C therapies and have advanced liver disease, according to findings from a large, four-year study presented today at the 43rd annual meeting of the European Association for the Study of the Liver (EASL).

24 Apr 2008

Nonalcoholic fatty liver disease related to cardiovascular fitness

Patients with nonalcoholic fatty liver disease (NAFLD) have suboptimal levels of cardiovascular fitness, muscle strength, body composition and physical fitness, according to a new study.

25 Mar 2008

Big increase in hepatitis C-related deaths in the United States

Hepatitis C-related deaths in the United States increased by 123 percent from 1995 through 2004, the most recent year for which data are available. Mortality rates peaked in 2002, then declined slightly overall, while continuing to rise among people 55 to 64 years old.

25 Mar 2008

Methamphetamine use and pulmonary arterial hypertension

The Pulmonary Hypertension Association (PHA), in conjunction with leading pulmonary hypertension specialists, has announced the launch of an educational campaign to raise awareness of the association between pulmonary arterial hypertension (PAH) and stimulant use, particularly methamphetamine use.

24 Mar 2008

African-American women less likely to reduce drinking during pregnancy

New Saint Louis University research found that although white women are more likely to drink or binge drink prior to pregnancy, African-American women are less likely to reduce drinking during pregnancy, which may be linked to a higher rate of fetal alcohol syndrome (FAS) among the population.

20 Mar 2008

Wine harder on the brain than beer

Scientists say wine damages the brain more than beer or spirits, because it particularly affects the hippocampus, the part of the brain associated with memory and spatial awareness.

17 Mar 2008

Combined therapeutic approach of stenting and photodynamic therapy improves survival in late stage liver cancer patients

A combined therapeutic approach of stenting and photodynamic therapy may improve survival rates for patients suffering from advanced liver bile duct cancer, according to a study published this month in Clinical Gastroenterology and Hepatology , the official journal of the American Gastroenterological Association (AGA) Institute.

12 Mar 2008

Rimonabant weight-loss drug might fight alcoholic fatty liver

The cannabinoid receptors best known for delivering the psychological effects of marijuana also explain the connection between chronic alcohol use and a buildup of fat in the liver, according to a report in the March issue of Cell Metabolism, a publication of Cell Press.

6 Mar 2008

Combination therapy of Prostacyclin, Sildenafil and Bosentan may treat portopulmonary hypertension

Combination therapy of Prostacyclin, Sildenafil, and Bosentan helped a young male patient with severe portopulmonary hypertension improve enough to receive a liver transplant.

6 Mar 2008

Serum fibrosis markers correlate with liver fibrosis stage in patients with advanced chronic hep C

A prospective study of patients with advanced chronic hepatitis C (CHC) revealed that a 3-variable model of serum fibrosis markers, including serum HA, TIMP-1 and platelet count, could identify cirrhosis with better accuracy than other published models.

4 Mar 2008

Elevated liver enzymes associated with higher future mortality

A new population-based epidemiological study has found that elevated liver enzymes discovered during routine medical care are associated with higher future mortality.

4 Mar 2008

Children's Hospital 1 of 10 pediatric hospitals in US selected to study liver disease in kids

Children's Hospital of Pittsburgh of UPMC has been selected to join an effort among select centers in the United States and Canada to collect and study information necessary to understand the possible causes and treatment of a destructive liver disease called primary sclerosing cholangitis (PSC).

27 Feb 2008